Search
Generic filters
All
Products
Blogs

September 13, 2019

6-OHDA rat models
Laboratory Techniques

6-OHDA rat models

Parkinson’s disease (PD) is the most common neurological disorder that is characterized by debilitating motor abnormalities, including muscle rigidity, resting tumor, stiffer voluntary movements, and postural instability. Primary neuropathological condition of PD includes progressive degeneration of the dopaminergic neurons in the nigrostriatal area. Experimental models of PD are specifically designed to gain detailed insights into the pathological mechanisms of the

Animal Models of Traumatic Brain Injury
Laboratory Techniques

Animal Models of Traumatic Brain Injury

Introduction The use of animal models for studying traumatic brain injury (TBI) has several advantages, including low breeding cost, easy maintenance, and innovative techniques to create genetically modified strains. Rodent models provide powerful tools to screen and characterize putative therapeutic targets in TBI. These models efficiently recapitulate several clinical features of TBI such as closed head injuries (CHI), diffuse and
Background-and-Significance-Section-of-Grant-Application
Conduct

Background and Significance Section of Grant Application

Writing a grant application requires real effort and time nowadays. With the growing competition each year, it demands true mastery. Right after selecting your research topic, you are supposed to devise a well-structured research plan. The quality of your plan will determine whether your research will be successful or not. National Institutes of Health (NIH) will award you with a
Challenges-of-Health-Investigators
Conduct

Challenges of Health Investigators

The scientific discourse has been abuzz with the ongoing discussion on young scientists and health investigators and the challenges they face. With the growing unpredictability of the economic climate, the biomedical research budget is shrinking every day. Both early-career investigators and established scientists are facing the worsening funding crisis, the hardest hit, however, are the health investigators pursuing careers in
Collecting-Preliminary-Data-for-the-Grants
Conduct

Collecting Preliminary Data for the Grants

To receive a grant award, you think of novel ways of highlighting your research application amongst all others. It is where preliminary research appears and acts as a power play for your grant proposal. Data for preliminary research is gathered via small-scale research to assess the protocols of your research. It gives your reviewers a small peek into your research
Rodent Craniotomy Protocol
Laboratory Techniques

Rodent Craniotomy Protocol

Introduction A craniotomy is a surgical procedure used to temporarily open a part of the skull to expose the brain for experimental manipulations. Research developments over the past two decades have made craniotomy safer, simpler, and more successful. In craniotomy, a bone flap is removed from the skull to reach the internal brain. Craniotomies are referred to as critical operations,
Conducting-Literature-Search-for-Grant-Application
Conduct

Conducting Literature Search for Grant Application

Literature Search is the lifeline of any grant proposal. It comprises sorting and sifting the history of past research and collecting useful and beneficial information. Not too long ago, the literature was persevered and available in the form of physical books only. But now, the technology has replaced it with the cloud data that is easily accessible via internet services
Controlled Cortical Impact for Traumatic Brain Injury
Laboratory Techniques

Controlled Cortical Impact for Traumatic Brain Injury

Introduction Traumatic brain injury (TBI) is referred to as alteration or dysfunctionality in brain function, or brain pathology resulted by external trauma or force. TBI is a serious health condition because of its complexity and wide-reaching effects, including lesions, necrosis, and axon degeneration. Research on traumatic brain injury has been challenging because no two injuries are identical, and it has