Anesthesia Components

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  • Anesthesia is defined as a temporary state of insensibility or loss of consciousness.
  • The requirements of the research procedures, species, age, and background of the animal being used determine the method and agent used to induce anesthesia.
  • In clinical practices, general anesthesia is preferred over local anesthesia since it results in loss of consciousness, analgesia, suppression of reflex activity and muscle relaxation.
  • Anesthesia can be induced using inhalant or injectable agents.
  • Anesthesia machine comprises a gas compressor, a regulator, a flow meter, a vaporizer, an anesthetic breathing system, and waste gas scavenging system.
  • Good anesthesia practices involve appropriate anesthesia management and monitoring techniques, and recovery care.
  • Neuromuscular blocking agents only produce paralysis. Thus efforts to monitor the depth of anesthesia is critical for humane treatment of the animals.
  • Anesthetization of pregnant animals can affect their fetuses. Anesthetics can result in serious acute and/or long-term effects on the fetus. The residual effects of the drugs in cesarean operation delivered fetus can cause sedation and depression of respiratory and cardiovascular systems.
  • Anesthetization of neonatal animals should take into consideration their increased vulnerability to hypothermia, usually low reserves of energy, possible poor pulmonary and circulatory function and reduced capacity to detoxify a wide range of anesthetic agent (certain species).