Anjali Singh, Author at Conduct Science

Laboratory Techniques Science

October 19, 2020

The 𝛾-radiation and its effects on chromosomes

Radiations have been extensively used in medical devices to look into the inner workings of the human body. Wilhelm Roentgen brought a revolution in the medical field by first developing an X-ray machine in 1895 after which, the first radiology department was set up. After the discovery of X-ray, various…

Anjali Singh

Laboratory Techniques Protocols Science

October 16, 2020

Drosophila: General Information and Methods for Experiments

Whoever thought that the small fly hovering over fruits will become such an essential asset for genetics research!! Fruit flies are one of the first extensively used model organisms in labs. Moreover, it is one of the first model organisms which was brought ‘from nature to labs’ to understand the…

Anjali Singh

Laboratory Techniques Science

October 12, 2020

The Spiral Structure of Chromosome

A Chromosome is an organized package of DNA, located inside the nucleus. The structure of a chromosome involves six essential parts, that include: Pellicle and matrix, chromonemata, chromomere, centromere, secondary constriction, and satellite body. So, chromonemata are the spiral structures that are embedded in the matrix of the chromosome and…

Anjali Singh

Laboratory Techniques Science

October 2, 2020

The Cytogenetics of Fungi

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Fungi is a group of eukaryotic organisms that include a myriad of single and multicellular organisms that are parasitic or saprophytic in nature. Over 1.5 million species of fungus have been discovered and they are found in a range…

Anjali Singh

Laboratory Techniques

September 28, 2020

Human Sex Chromosomes and X-inactivation

Chromosomes are thread-like structures, located in the nucleus, which carry hereditary information in the form of genes. Structurally, it is composed of ‘packaging proteins and DNA molecules’, and it is represented in different shapes and numbers which vary among different living organisms. For example, bacteria have circular chromosomes, whereas organisms…

Anjali Singh

Laboratory Techniques Protocols Science

September 25, 2020

Estimating the Chiasma Frequency in Diplotene-Diakinesis Stage

Chiasma is the point of crossing over or site where the exchange of genetic material takes place between two homologous, non-sister chromatids. The crossover occurs in the pachytene stage, however, it is observed in the diplotene stage of meiosis-I. The cross over between the two homologs also creates a new…

Anjali Singh

Laboratory Techniques Protocols Science

August 10, 2020

Clinical Cytogenetics – Pt.2: A Study of Chromosomal Aberrations

Since the discovery of chromosomes, the cytogenetic field has evolved rapidly. The techniques have unfolded several hidden mysteries of chromosomes. And later, it gave rise to two branches: molecular and clinical cytogenetics. The studies in clinical cytogenetics suggested that the structural and numerical aberrations of chromosomes (autosomal and sex) are…

Anjali Singh

Laboratory Techniques Protocols Science

August 10, 2020

Clinical Cytogenetics – Pt.1: A study of chromosomal aberrations

As we know, cytogenetics is the study of chromosomal structure and behavior by using different staining techniques. In the year 1962, Lejeune proved Waardenburg’s hypothesis (the cause of Down syndrome could be a chromosomal aberration) by reporting the first case of syndrome due to chromosomal aberrations. It was a major…

Anjali Singh

Laboratory Techniques Protocols Science

April 20, 2020

Cytogenetics: An advanced technique to color Chromosomes

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Cytogenetics is the study of the structural and functional properties of the chromosome. It includes chromosomal structure, function, behavior - during mitosis and meiosis, and influence on the phenotype of an organism. It is used as a tool to…

Anjali Singh

Laboratory Techniques Protocols Science

April 15, 2020

Molecular Cytogenetics: in situ hybridization-based technology

Cytogenetics was introduced in 1900 as a tool to determine the correct number of chromosomes of an organism. Since the 1970s, it has been used to detect clinical syndromes; it helped to understand the chromosomal aberrations and phenotypes associated with it. Karyotyping was the first cytogenetics tool used to study…

Anjali Singh

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Anjali Singh

The 𝛾-radiation and its effects on chromosomes

Drosophila: General Information and Methods for Experiments

The Spiral Structure of Chromosome

The Cytogenetics of Fungi

Human Sex Chromosomes and X-inactivation

Estimating the Chiasma Frequency in Diplotene-Diakinesis Stage

Clinical Cytogenetics – Pt.2: A Study of Chromosomal Aberrations

Clinical Cytogenetics – Pt.1: A study of chromosomal aberrations

Cytogenetics: An advanced technique to color Chromosomes

Molecular Cytogenetics: in situ hybridization-based technology

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