The tail suspension test is a standard test of depression. Mice and Rats are hung to the apparatus and time struggling is an approximate measure of depression. Escape oriented behaviors are quantified during measurement. The tail-suspension test is a highly validated test for potential antidepressant pharmaceutical compounds
Easily customization. IR and fluorescent backlights available. Please inquire for more details.
Flat Bottom Restrainers are manufactured from perspex cylinders mounted on a flat black perspex base. The restrainers give access through both extremes, by opening the respective tilting door that is fixed by a screw at the upper part of the restrainer. Rodents can be immobilised by sliding the doors along the restrainer. A slot in the base of the door allows for the whole tail to be available for the pulse transducer and cuff installation, the i.v. drug administration or blood extraction.
The easy operation of the doors and its disposition on the extremes of the restrainer makes the manipulation of the animal convenient and avoids the animal to be dragged backwards, protecting it from injuries.
The SCI device is constructed using a steel impounder inserted into a Teflon base. The impounder is attached to the end of the hollow tube by a horizontal pin to guide the weight and to prevent it from bouncing on impact. The weight is made of Teflon coated stainless steel and is supported by a removable pin which is also used to release the weight. Rod magnet is used for retrieval of the weight after the injury.