The tail suspension test is a standard test of depression. Mice and Rats are hung to the apparatus and time struggling is an approximate measure of depression. Escape oriented behaviors are quantified during measurement. The tail-suspension test is a highly validated test for potential antidepressant pharmaceutical compounds
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Open Field test is a popular protocol used to assess exploratory behavior and anxiety. Thigmotaxis in the open field is used to evaluate anxiolytic, anxiogenic and even non-pharmacological treatments. Ambulation is the most common behavior studied with this maze, but others such as latency or rearing can also be measured. In addition, objects can be added for a modification similar to the novel object recognition field.
Walls can be both opaque or clear. We recommend that clear walls are used for measurements of anxiety, while opaque walls are used if assessments include novel object recognition.