Touch Screen Constant Laboratory Syringe Pump

SKU ME-CSP-01 Categories , Tags

The ConductScience Touch Screen Constant Laboratory Syringe Pump is a precision instrument designed for accurate and reliable fluid delivery. Available in both single and dual models, it offers a wide range of linear velocities and stroke resolutions to accommodate different application needs. The pump features a push-pull working mode and flow correction program for more accurate liquid volume. It also has a built-in selection of syringe model, and offers syringe customization options. The communication interface and status signal output provide easy control and monitoring of the pump. With a compact design and wide voltage AC power supply, the ConductScience Touch Screen Constant Laboratory Syringe Pump is an ideal solution for various scientific and medical applications.

ConductScience offers the Syringe Pump

$1,490.00$1,690.00

Description

Model

CS-LSP01-1C

CS-LSP02-1C

Channels12
Syringe Type10 ul to 60 ml10 ul to 60 ml
Fuse5 x 20 mm - 250 V~ - Fast - 1A5 x 20 mm - 250 V~ - Fast - 1A
Drive SystemMicroprocessor-controlled 16-subdivision stepper motor with screw connected to synchronous beltMicroprocessor-controlled 16-subdivision stepper motor with screw connected to synchronous belt
Micro-step Size0.156 micron per 1/16 step0.156 micron per 1/16 step
Liquid Dispensing per 1/16 step0.0919μl (60ml BD syringe)0.0919μl (60ml BD syringe)
Max Step Speed867 steps/sec867 steps/sec
Min Step Speed1 step/30 secs1 step/30 secs
Linear Speed RangeMin: 5um/min Max: 13 cm/minMin: 5um/min Max: 13 cm/min
Flow Rate Range0.831 nl/min to 43.349 ml/min (60ml syringe)0.831 nl/min to 86.67 ml/min (60 ml syringe)
Linear Thrust>280N>280N
Dimensions280x210x140 (mm)280x250x140 (mm)
Weight3.9kg4.5Kg
Temperature5°C - 40°C (41°F - 104°F)5°C - 40°C (41°F - 104°F)
Humidity20% - 80% RH20% - 80% RH
Operating ModesInfusion, Withdrawal, Infusion then Withdrawal, Withdrawal then Infusion, ContinuousInfusion, Withdrawal, Infusion then Withdrawal, Withdrawal then Infusion, Continuous
Description

Infusion pumps study the physiological and pharmacological characteristics of biological or pharmacological substances in-vivo.

A Syringe Pump is a type of infusion pump which is a small infusion device that is used to gradually administer specific amounts of fluids for use in chemical and biomedical research. It includes an outer syringe attached to the subject’s catheter. Syringe pumps either withdraw or push out fluid via a syringe to obtain a predetermined volume depending on the size of the syringe. The pressure that a syringe pump can produce is a function of the pump’s force and also the physical attributes of the syringe and the setup utilized.

Device Parameters
ParameterValue
Working modePush-pull mode (filling, extraction)
Execution unit volume2
Stroke resolution0.156μm
Linear velocity range5μm/min-130mm/min
Flow rate range0.831nl-150.5ml/min
Stroke control accuracyError ≤ ± 0.5% (when stroke ≥ 30% of max stroke)
Flow correctionYes
Syringe selectionBuilt-in main manufacturers and models
Applicable power supplyWide voltage AC90-265V, 50Hz/60Hz
Status signal output2-way OC door signal output
Working environmentTemperature 0~40℃, relative humidity < 80%
Driver weight4.5 Kg
Communication interfaceRS485 (Modbus protocol)
Maximum stroke140 mm
Display parameter settingLiquid volume, flow rate, or linear speed
Linear speed adjustmentResolution of 5μm/min
Rated linear thrust>180 N
Operating parameter settingDispensing liquid volume, injection time, etc.
Syringe customizationAvailable
Control model input2-way start-stop control input terminals - 1-way falling edge trigger signal to control - start-stop; 1-way TTL level signal to control - start-stop
Dimensions (L×W×H)280 x 250 x 140 (mm)
Power consumption20 W

Documentation

Introduction

Syringe pumps are utilized to study the physiological characteristics of biological substances in vivo. Two distinct types of infusion pumps are present: syringe pumps and implantable pumps. A syringe pump is a small infusion device that is used to gradually administer specific amounts of fluids for use in chemical and research. It includes an outer syringe that is attached to a catheter from the animal. Syringe pumps either withdraw or push out fluid via a syringe to obtain a predetermined volume depending on the size of the syringe. The pressure that a syringe pump can produce is a function of the pump’s force and also the physical attributes of the syringe and the setup utilized.

Over the years, a variety of vascular infusion and intravascular delivery methods have been utilized in rodents with varying amounts of success in research. Since rodents are the most extensively used animal species in research, it is reasonable to anticipate that the need for enhancing the techniques for vascular infusion systems in rodents will advance in the future. Fundamental research in fields like neuroscience, physiology, pharmacology, virology, immunology, and oncology utilizes substantial quantities of rodents to evaluate the impact of biological and active agents. A significant number of these studies depend on vascular infusion technology or to develop samples for the evaluation of movement, biodistribution, and plasma duration.

A syringe pump is the standard instrument for administering intravenous doses to rats and mice given its capacity to deliver small volumes accurately. In essence, the device guarantees the precise administration of solutions. When the animal is set up for infusion or sample withdrawal, infusion and withdrawal techniques can be performed using manual or automated procedures. Manual infusion is performed with the syringe pump as syringes are connected to the catheters or pumps, which in turn can be attached to give unattended infusion.

The characteristics of a syringe pump vary extensively with regard to design type, flow rate, and precision. Types of designs include a syringe, peristaltic, and piston pumps. Syringe pumps make use of a worm drive system, which drives the plunger of a standard syringe at a modifiable rate. Syringe pumps have a tendency to deliver low levels of flow with an accuracy of ±2%. The device can also be utilized for tethered infusion, where animals can be tethered for long-duration infusions ranging from a span of several weeks to months. Syringe pumps can be set up for continuous pumping by using a reciprocating pumps program so that two pumps can be utilized together to make a constant infusion framework. This mode enables one pump to infuse while the other one withdraws.

There are two major types of syringe pumps: the infusion pump and the research syringe pump. The infusion pump is basically designed for the delivery of controlled amounts of fluids, for example, nutrients and other solutions to patients. They are principally used for in vivo analysis, treatment, and research studies. On the other hand, research syringe pumps or modern laboratory pumps are instruments utilized in research labs for applications that need very small amounts of fluid deliveries. Research pumps generally manage smaller volumes and provide additional characteristics that promote research yet are unfeasible for in vivo use. Moreover, the device offers better precision, a continuous flow, and much better accuracy than its syringe counterparts.

Principle

As is evident by its name, the primary component of the syringe pump is the syringe. This instrument has been extensively utilized in medical settings for quite a long time. However, on its own, the syringe entails a hand-driven movement of the piston, which is not appropriate for a controlled administration of its contents. The syringe pump was developed to resolve this issue. It comprises a straightforward source of linear motion that controls the speed at which the piston is driven.

If the diameter of the syringe is known, the device adapts its linear speed to the required flow rate. The strength of the syringe pump lies in the fact that the user can effortlessly adjust the working range of the device by altering the diameter of the syringe. Generally, a smaller diameter syringe allows better control at lower flow rates yet at smaller dispensable volumes.  In contrast, a larger diameter allows control at larger volumes however reduces the performance of the device at low flow rates.

In addition, syringe pumps have the ability to determine the flow rate effectively. While changing flow rates, the piston pushes the syringe resulting in an increased amount of pressure in the fluidic system, and it is deformed instead of placing the fluid into motion. The flow stability of a syringe pump is decided by the negligible motion of its motor. Since the displacement of the piston and the injected volume are connected, this negligible motion incites an insignificant infused volume. In this way, distinct phenomena which resemble oscillations or pulses show up at low flow rates because of the motor step.

A syringe pump, like other infusion frameworks, can be largely described by its settling time and its dependability. The settling time of a syringe pump depends on the value of its mechanics, as well as, and all the more importantly, on the fluidic resistance and the fluidic compliance of the entire experimental system. It is important to remember that the elasticity in the system allows a smoother flow rate and improves its stability, but reduces its responsiveness. Hence, to obtain the best responsiveness with a syringe pump, elasticity in the fluidic framework must be prevented and the fluidic resistance of the chip ought to be reduced.

History

For more than a period of 50 years, researchers and scientists have utilized syringe pumps, with their capability to modulate the flow of fluids on a small level, to save lives and execute high-impact research studies. Initially, scientists created infusion pumps, of which syringe pumps are one type, for controlled delivery of substances. In 1658, Christopher Wren developed the first infusion pump, but the development was slow due to technical restrictions, substandard transfusions, and bans imposed by the government. New models appeared in the 19th century, and an infusion pump was first utilized for chemotherapy in the 1950s. Electronic pump development, product upgrades, and miniaturization of the pumps in the 1980s – 1990s expanded the use of infusion pumps in research.

Precautions

To ensure the appropriate working of the plenum vaporizer systems, it is important that the system is supplied with pressurized gas. The vaporizer must be correctly attached, and locking mechanisms must be fully engaged to avoid any leakage of the agent and the gas. Vaporizers must not be overfilled or underfilled to prevent failure of the vaporizer systems. It is also important to ensure that the correct anesthetic agent is used to prevent over-or under-dosing the subject. Regular servicing of the vaporizer is also critical for its proper functioning.

Apparatus and Equipment

The ConductScience Touch Screen Constant Laboratory Syringe Pumps are designed to provide precise and reliable liquid handling solutions for various applications. The equipment operates in a push-pull mode, enabling filling and extraction processes with ease. The execution unit volume is 2, with a stroke resolution of 0.156μm and a linear velocity range of 5μm/min-130mm/min. The flow rate is calculated by multiplying the linear velocity with the inner cross-sectional area of the syringe.

Our apparatuses are made with high-quality materials, ensuring durability and longevity. The driver unit weighs 4.5Kg and has a rated linear thrust of >180N, providing sufficient force to handle different liquid viscosities. The equipment can handle a flow range of 0.831nl-150.5ml/min, making it suitable for various applications.

We provide a wide selection of built-in syringes from main manufacturers and models for selection. The syringe customization option is also available to meet specific requirements. The equipment is designed to be compatible with a wide voltage AC90-265V, 50Hz/60Hz power supply.

The apparatus comes with a communication interface to facilitate communication with other devices. The maximum stroke of the equipment is 140mm, and it has a flow correction feature that utilizes a correction program to obtain a more accurate liquid volume.

The display parameters can be easily set to liquid volume, flow rate, or linear speed, making it convenient for users to monitor and adjust the equipment’s operation. The linear speed adjustment resolution is 5μm/min, and the operating parameter setting includes dispensing liquid volume, injection time, and more.

The device status signal output is a 2-way OC door signal output, which indicates the start-stop and direction status. It operates in a temperature range of 0~40℃, with a relative humidity of less than 80%. The dimensions of the equipment are 280x250x140 (mm), with a power consumption of 20W.

Protocol

Primarily, the aim of the syringe pump is to progressively administer precise doses of solutions while controlling the flow rate.  To ensure that the syringe pump can successfully accomplish its purpose, place the device on a clean and level surface.  Now, connect the power cord. Before turning the pump on, attach it to the electric switch utilizing the power cable. Attach the end of the power cord to the main socket at the back of the syringe pump. Now take the plug and attach it to the electric mains. Turn on the mains switch. The touchscreen display will indicate that the power is connected to the pump.

  1. Before use, ensure that the apparatus is connected to a suitable power supply and that the environment meets the working conditions specified in the product description.

  2. Select a suitable syringe from the available one for use with the apparatus.

  3. Set the desired display parameters for liquid volume, flow rate, or linear speed as required.

  4. Adjust the linear speed using the resolution of 5μm/min.

  5. Configure the operating parameters for dispensing liquid volume, injection time, etc.

  6. To input directly into the injector via the control model input, use the 2-way start-stop control input terminals, the 1-way falling edge trigger signal to control start-stop, and the 1-way TTL level signal to control start-stop.

  7. Once the apparatus is ready for use, fill the syringe with the desired liquid.

  8. Place the syringe in the apparatus, making sure that it is securely in place.

  9. Set the stroke resolution and linear velocity range as required.

  10. Ensure that the stroke control accuracy is set to error ≤ ± 0.5% (when stroke ≥ 30% of max stroke).

  11. Use the push-pull mode (filling, extraction) to control the flow rate, within the range of 0.831nl-150.5ml/min.

  12. Use the flow correction program to obtain more accurate liquid volume if necessary.

  13. Monitor the status signal output, which provides 2-way OC door signal output, indicating start-stop and direction status.

  14. Once the required volume of liquid has been dispensed or extracted, stop the apparatus.

  15. Remove the syringe and dispose of any unused liquid appropriately.

  16. Clean the apparatus and syringe as required, following instructions.

  17. Store the apparatus and syringe in a suitable location until required for future use.

Frequently Asked Questions

See our syringe pump frequently asked questions here.

Applications

The next step is to make sure that the syringe is loaded accurately. Pinch and hold together the clutch lever that releases the clutch and force the syringe driver away until it touches the end of its track. Hold the clear syringe clamp; pull upward making room for the syringe in the syringe saddle. First, put it in the syringe barrel. Ensure that the syringe finger tabs are held by the metal holding spring, and discharge the syringe clamp in order to hold the syringe in the saddle safely. Pinch together the clutch lever and allow the syringe driver to progress forward until the point when the syringe driver touches the end of the disposable syringe plunger. Discharge the clutch lever so that the holding bars secure the end of the plunger to avoid siphoning. The syringe is at the moment correctly loaded.

Now, the syringe pump needs to be switched on. To turn on the pump, push the on button on the keypad. The instant you turn the pump on, it undergoes a self-test displaying various characters on the screen. When the self-test is finished, it will show on the screen. The infusion settings of the pump can be customized in a menu-driven procedure. The user can browse the rate modes provided on the start-up list; these modes are the most frequently utilized rate modes. The user can likewise utilize the option to select from saved programs, or the option to browse the list of additional standard rate modes.

After the pump has been successfully turned on, push the key to detect the syringe size and display it automatically. Ensure that the syringe size has been accurately identified. Program the delivery limit with the number or arrow keys and utilize the keys to verify the number. In the event that a delivery limit isn’t required, enter 0. Program the bolus amount with number or arrow keys and utilize the keys to verify the number. In the event that a bolus isn’t required, enter 0. Program the infusion rate with number or arrow keys, and press the keys to validate the rate.

Prior to beginning a delivery, the syringe should be primed to eliminate any residual air within the syringe tip and the infusion extension set and to remove any mechanical slack. Ensure that the infusion line is not attached to the subject when priming. Push the prime key to begin the process of priming. Leave the prime key as soon as all the air has been removed, and fluid starts to flow out of the infusion line. Now connect the catheter to the subject. Initiate the process of delivery by selecting the delivery option. Selecting the stop button will cease the process of delivery. Push and hold the power off button to turn off the pump. If the ac power is utilized, the pump will go into power-off/standby mode. In case the battery power is drained out, the pump will turn off.

A major advantage of the syringe pumps is that they can be utilized in nearly every application that involves accurate metering, particularly at the microscale and the nano-scale. They are utilized in many chemical and biomedical research areas as precise dosing procedures or to precisely administer small amounts of reagents, mix minuscule volumes, and add trace amounts of specific chemicals throughout the duration of the research experiment.

Syringe pumps can also be utilized for scale-up, developing new materials, and classification of materials in chemical, pharmaceutical, catalysis, and materials science experiments. The device can additionally play a key role in reducing errors in the areas of microanalysis and instrumental analytics, for example, mass spectrometry (MS), high-performance liquid chromatography (HPLC), and liquid chromatography-mass spectrometry (LC-MS).

Continuous intravenous infusion is possibly one of the most well-known applications of the syringe pump. The syringe pump apparatus can be utilized for intermittent mouse intravenous dosing, continuous mouse infusion, intermittent rat intravenous dosing, and continuous rat infusion. The device can also be used for continuous rat infusion plus blood sampling where the researcher can catheterize two separate vessels and utilize a two-channel system to accumulate manual blood samples outside the cage without causing any stress to the animal.

In addition, syringe pumps that are well-suited for micro-fluidic applications are present in the market, which assists research in areas like micro-environmental control. Syringe pumps can further facilitate accurate infusion in medical and biomedical research; for example, feeding small animals or administering small doses to particular locations in the brain in neuroscience experiments. Moreover, syringe pumps are helpful for speeding up the research and reducing inaccuracies during fluid delivery in many sophisticated research fields.

Furthermore, the syringe pumps have proved themselves useful in facilitating research involving animal models and in veterinary medicine. The device is used in studies to deliver intravenous solutions, to deliver perioperative solutions, administer various doses for research experiments accurately, and epidural administration. Epidural catheters are presently utilized in veterinary medicine in special cases to give spinal analgesia. The syringe pump also facilitates the administration of fluids products to very small animals as the traditional means can risk the overdose of fluids to smaller animals. The instrument has turned out to be a valid alternative.

Strengths

  • The foremost strength of the syringe pumps lies in the fact that they have the ability to provide increased accuracy and precision. Also, syringe pumps are very easy to utilize. Not only does the device offer accurate dosing but it also requires no dilution and less wastage of the solutions.  In addition, this system permits constant infusion of fluids at a continuous rate. It is also easy to vary the infusion rate and the infusion solution.
  • Offers high precision and small flow rate for biological laboratories
  • Provides a friendly man-machine interface, large-screen display, and digital knob for easy and fast operation
  • Features traffic jam protection function, liquid volume calibration function, and syringe protection function

Limitations

  • Limited to the biological laboratory environment
  • Requires communication bus for control

Summary

The ConductScience Touch Screen Constant Laboratory Syringe Pump is a micro-volume syringe pump designed for biological laboratories, offering high precision and a small flow rate for liquid transmission. It comes with a friendly man-machine interface, a large-screen display, and a digital knob for easy and fast operation. The pump features a traffic jam protection function, a liquid volume calibration function, and a syringe protection function. It uses a communication bus and can be connected to the host computer and controlled by the background software.

References

 

  1. Abe, C., Tashiro, T., Tanaka, K., Ogihara, R., Morita, H. (2009). A novel type of implantable and programmable infusion pump for small laboratory animals. Journal of Pharmacological and Toxicological Methods, 59, 7–12. doi:10.1016/j.vascn.2008.09.002
  2. Nolan, T. E., Klein, H. J. (2002). Methods in Vascular Infusion Biotechnology in Research with Rodents. ILAR Journal, 43(3), 175–182.
  3. Pablo, L. S. (n. d.).  Hows and Whys of Cri Analgesia in Small Animals. Retrieved from https://www.acvs.org/files/proceedings/2011/data/papers/157.pdf
  4. Dey, R. (2015). Syringe Pump. Retrieved from https://www.slideshare.net/biomedicz/roll-no-15-50105813
  5. Moens, Y. (2004). Syringe Pumps for Anaesthesia/Analgesia: Toy or Tool? Retrieved from https://www.vin.com/apputil/content/defaultadv1.aspx?pId=11181&id=3852114&print=1

Additional information

Channels

Dual Channel, Single Channel

Mode

Infusion Only, Infusion-Withdrawal

Brand

ConductScience

Product Application

Analytical Instruments, Cell culture studies, Drug Delivery, Microinjection

Volts

110V, 240v

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