- The T-Maze is a simple single-point two-choice maze.
- The task exploits the innate explorative nature of rodents and subjects them to tasks that require them to alternate between the goal arms to retrieve food rewards.
- Commonly used protocols with the T-maze are Forced Alternation task and Spontaneous Alternation task.
- The T-Maze can be easily adapted to investigate the different aspects of spatial learning and for different subjects.
- By using guillotine doors, the T-Maze can be easily adapted for Delayed Alternation protocol.
- The T-Maze has been extensively used in the study of hippocampal functions, age-related cognitive decline, and anxiety.
- The T-Maze is also utilized in understanding the effects of drugs and toxins and in the understanding underlying pathology of diseases on spatial learning and memory.
- Subjects of the diseased model show a much slower learning curve in comparison to the control group in T-Maze tasks.