Lab-on-a-chip guide

Choose the microfluidic chip, pump, and setup for your experiment.

Start with your workflow, then choose the chip format, flow-control setup, accessories, and support needed to run it.

Transparent microfluidic chip with connected tubing

Chip and tubing reference

Transparent device, inlet path, and benchtop setup context.

Microchannel routing map

Workflow to setup path

SampleBufferCellsMixerCollect
Aqueous
Sample
Biology

Setup planning

A chip recommendation is incomplete without the setup around it.

Plan the chip, pump, tubing, holder, protocol, and quote path together so the full setup is clear before ordering.

Setup overview

Use this overview to keep the required components aligned from selection to quote.

PumpTubingChipHolderCollect
Setup PartWhat the User ChoosesRoute
ChipFormat, material, channel layout, ports, and optical path.Open path
Flow controlSyringe pump, pressure pump, peristaltic pump, or existing instrument match.Open path
Fluid pathTubing, fittings, connectors, short fluid path, collection supplies.Open path
FabricationSpin coating, bonding, hot plates, plasma treatment, and PDMS processing.Open path
ProtocolPriming, flow-rate range, imaging, cleaning, and bubble prevention.Open path
Quote pathStock item, configured bundle, or custom technical review.Open path

Material decision

Compare materials like an engineering decision.

Material choice changes optical performance, solvent exposure, cell behavior, and fabrication path. Keep this as a real comparison table.

PDMS

Best fit
Cell culture, fast prototyping, optical microscopy, gas exchange.
Check before ordering
Small molecule absorption, surface treatment, swelling, reuse expectations.
Decision note
Often the first prototyping route for biology-focused chips.

PMMA

Best fit
Rigid polymer chips, teaching labs, disposable assays, lower-cost runs.
Check before ordering
Solvent compatibility, bonding method, temperature exposure.
Decision note
Useful when a rigid disposable format matters more than gas exchange.

Glass

Best fit
High optical clarity, solvent resistance, pressure tolerance, droplet work.
Check before ordering
Cost, fragility, connector and holder requirements.
Decision note
Strong default when imaging and chemistry both matter.

Silicon / quartz

Best fit
Thermal, optical, or chemically demanding specialty workflows.
Check before ordering
Application-specific fabrication and quoting constraints.
Decision note
Usually needs a technical review before ordering.

Paper

Best fit
Low-cost diagnostics, environmental testing, colorimetric field assays.
Check before ordering
Whether the assay truly needs open porous flow vs closed channels.
Decision note
Best for quick detection tests and field-style readouts.

Application notes

Application notes for common workflows.

Each note shows the workflow, products, difficulty, and checks before ordering.

DropletsIntermediate

Droplet generation starter workflow

Droplet chip, syringe or pressure pump, tubing, oil/surfactant review.

Starter setup available

Cell cultureIntermediate

PDMS cell culture perfusion workflow

PDMS chip, sterile tubing, bubble prevention, microscope holder.

Technical review recommended

Drug screeningAdvanced

8-channel drug screening gradient workflow

Gradient chip, multi-channel pump, connector plan, imaging setup.

Configuration support available

MaterialsFoundational

Choosing PDMS vs PMMA vs glass chips

Material comparison, solvent check, optical check, quote criteria.

Selection guide available

Custom review

Request technical review when a standard catalog setup is not enough.

Share the workflow details, materials, flow rates, and detection needs required for a custom chip or setup quote.

What we review

MaterialInlet countWidth / depthDetection pathOutlet / collectQuantity
Workflow
Target material
Sample type
Flow-rate range
Imaging or detection method
Sterility or biocompatibility
Quantity
Drawing or reference chip

Next step

Use the Chip Finder to turn a workflow into a setup sheet.

Open Chip Finder