Weight Drop TBI models are used to replicating focal cerebral contusions as well as traumatic, diffuse brain injury by axonal damage. Attach a metal loop to the top end of the desired weight allowing the fishing line to be fastened to the weight. The plastic guide tube is held in place with a clamp stand and positioned above the scored tin foil. The fishing line is then attached through the metal loop to the weight ensuring that the bottom of the weight hangs freely over the scored tin foil. The fishing line is then connected to the clamp stand, and the weight is drawn up through the plastic guide tube with the fishing line and secured in its position with an Allen key pin.
The SCI device is constructed using a steel impounder inserted into a Teflon base. The impounder is attached to the end of the hollow tube by a horizontal pin to guide the weight and to prevent it from bouncing on impact. The weight is made of Teflon coated stainless steel and is supported by a removable pin which is also used to release the weight. Rod magnet is used for retrieval of the weight after the injury.
The Weight Drop TBI apparatus generally consists of two main parts: the U-shaped Plexiglas box and a collection sponge.
The typical weight drop mTBI equipment consists of a U-shaped Plexiglas stand, a plastic guide tube, brass weights, a clamp stand, a fishing line, and a collection sponge. The lightly anesthetized rodent is placed supine on a scored tin foil with its head directly in the pathway of the falling weight.
ConductScience offers the Weight Drop TBI apparatus.
