Techniques
Nuclear Magnetic Resonance Spectroscopy
Reference to this article: ConductScience, Nuclear Magnetic Resonance Spectroscopy (2019). doi.org/10.55157/CS20191121 Two molecules may have the same number and type of atoms, but their properties would
Quinolinic acid rat HD model
Introduction Huntington’s disease (HD) is an inherited autosomal dominant neuropathological disease caused by a mutation in the huntingtin gene (htt). Preclinical animal models are necessary for
3-Nitropreopionic acid Huntington’s disease model
Introduction 3-Nitropropionic acid (3-NP) is a selective striatal neurotoxin used in rodents to mimic pathological features of Huntington’s disease. 3-Nitropropionic acid interrupts the mitochondrial electron transport
Weight Drop Injury Model
Introduction Traumatic brain injury (TBI) is one of the most common brain injuries caused by an external impact or pressure, such as rapid acceleration or deceleration,
6-OHDA rat models
Parkinson’s disease (PD) is the most common neurological disorder that is characterized by debilitating motor abnormalities, including muscle rigidity, resting tumor, stiffer voluntary movements, and postural
Animal Models of Traumatic Brain Injury
Introduction The use of animal models for studying traumatic brain injury (TBI) has several advantages, including low breeding costs, easy maintenance, and innovative techniques to create
Rodent Craniotomy Protocol
Introduction A craniotomy is a surgical procedure used to temporarily open a part of the skull to expose the brain for experimental manipulations. Research developments over
Controlled Cortical Impact for Traumatic Brain Injury
Introduction Traumatic brain injury (TBI) is referred to as alteration or dysfunctionality in brain function, or brain pathology resulting from external trauma or force. TBI is
Fluid Percussion Injury
Need impactors for your experiments? Click here Introduction The fluid percussion injury (FPI) model is a widely used study model for traumatic brain injury. FPI model
Huntington’s Disease Rodent Models
Introduction ]Huntington’s disease (HD) is an inherited genetic neurological disorder characterized by cognitive dysfunction, abnormal body movements, progressive cell death, and neurodegeneration of the striatum and
Parkinson’s Disease Rat Models
Introduction Parkinson’s disease (PD) is a common neurodegenerative disease characterized by the loss of 50% to 70% of the dopaminergic neurons in the substantia nigra pars
Coomassie Brilliant Blue Stain Protocol
Introduction Coomassie brilliant blue (CBB) stain is a widely used method for routine visualization of proteins separated on polyacrylamide gels. It is an organic dye that