Techniques - Conduct Science

September 12, 2020

Can You Divide a Strand of Hair? The Ultramicrotome

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Microtomes are specifically designed devices for the cut of extremely thin sections from samples, for the study of their microscopic composition. Samples can be of biological origins, such as tissues, cells, and tumors, but are not limited to it.…

Adélia Mendes

Laboratory Techniques Protocols Science

August 10, 2020

Clinical Cytogenetics – Pt.2: A Study of Chromosomal Aberrations

Since the discovery of chromosomes, the cytogenetic field has evolved rapidly. The techniques have unfolded several hidden mysteries of chromosomes. And later, it gave rise to two branches: molecular and clinical cytogenetics. The studies in clinical cytogenetics suggested that the structural and numerical aberrations of chromosomes (autosomal and sex) are…

Anjali Singh

Laboratory Techniques Protocols Science

August 10, 2020

Clinical Cytogenetics – Pt.1: A study of chromosomal aberrations

As we know, cytogenetics is the study of chromosomal structure and behavior by using different staining techniques. In the year 1962, Lejeune proved Waardenburg’s hypothesis (the cause of Down syndrome could be a chromosomal aberration) by reporting the first case of syndrome due to chromosomal aberrations. It was a major…

Anjali Singh

Laboratory Techniques Science

April 27, 2020

Classical Histology: Concepts, Methods, and Applications

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Introduction Histology is a routine lab technique used to evaluate the morphology and structure of cells, tissues, and organs under the microscope. Histological studies of biological samples often lead to the establishment of structure/function relationships, which may have diagnostic…

Adélia Mendes

Laboratory Techniques Protocols Science

April 20, 2020

Cytogenetics: An advanced technique to color Chromosomes

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Cytogenetics is the study of the structural and functional properties of the chromosome. It includes chromosomal structure, function, behavior - during mitosis and meiosis, and influence on the phenotype of an organism. It is used as a tool to…

Anjali Singh

Laboratory Techniques Protocols Science

April 15, 2020

Molecular Cytogenetics: in situ hybridization-based technology

Cytogenetics was introduced in 1900 as a tool to determine the correct number of chromosomes of an organism. Since the 1970s, it has been used to detect clinical syndromes; it helped to understand the chromosomal aberrations and phenotypes associated with it. Karyotyping was the first cytogenetics tool used to study…

Anjali Singh

Laboratory Techniques Protocols Science

April 13, 2020

Biomolecular NMR Spectroscopy

The information about the structure, interactions, and dynamics of biomolecules (protein, DNA, and RNA) is essential for understanding cellular processes. This knowledge is deconvolved by scientists and used in elucidating cellular mechanisms for finding cures for human diseases. The pharmaceutical industry, for example, uses this structural information to improve on…

Jaspreet Singh Grewal

Laboratory Techniques Protocols Science

April 7, 2020

Histochemical Techniques to Demonstrate Minor Compounds

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Introduction Minor compounds, also known as “Minerals or Micronutrients”, are required by living organisms, in a small amount, for their growth and development. Depending on the concentration, that is required to perform a function in an organism, minerals are…

Anjali Singh

Laboratory Techniques Protocols Science

March 31, 2020

Histochemical Techniques to Demonstrate Lipids

As an Amazon Associate, ConductScience Inc. earns revenue from qualifying purchases Introduction Lipids are biomolecules having a diverse group of organic compounds that include fatty acids, waxes, phospholipids, glycolipids, and sterols. These compounds are insoluble or poorly soluble in water due to the presence of long hydrocarbon chains in their…

Anjali Singh

The light digital microscope can be used to visualize structures as small as ~1 micron

Lab Basics Laboratory Techniques Science

March 9, 2020

Bright field microscopy

Microscopy is used to visualize objects that are too small to see with the naked eye. In biology, this technique enables us to examine things like bacteria and cells at a magnification of up to 10000 times their original size (BIO1000F practical manual, 2017). In light microscopy, visible light is…

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Can You Divide a Strand of Hair? The Ultramicrotome

Clinical Cytogenetics – Pt.2: A Study of Chromosomal Aberrations

Clinical Cytogenetics – Pt.1: A study of chromosomal aberrations

Classical Histology: Concepts, Methods, and Applications

Cytogenetics: An advanced technique to color Chromosomes

Molecular Cytogenetics: in situ hybridization-based technology

Biomolecular NMR Spectroscopy

Histochemical Techniques to Demonstrate Minor Compounds

Histochemical Techniques to Demonstrate Lipids

Bright field microscopy

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