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Cross-Species ComparisonFree in-browser calculator

Lab Animal Age Converter.

Convert animal age to human-equivalent age across mouse, rat, and zebrafish. Cross-species comparison, bidirectional conversion, strain-specific lifespan factors, and life-stage classification.

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Validated2026-04-09
CitableMethods and citation included

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Mouse Age

Conversion

Mouse age
126 d
18.0 wk · 4.1 mo
Human-equivalent
28 human years
Dutta & Sengupta (2016)
Life stage
Young adult (6 wk–6 mo)
Strain C57BL/6J
Lifespan position
16%
of strain median

Position on Strain Lifespan

NeonatalPre-weaningJuvenileYoung adultMature adultMiddle-agedSenescentMedian

Cross-Species Comparison

Equivalent biological age across all species (anchored to 28 human years)

SpeciesStrainAge (days)Age (months)Life StageLifespan %
Mouse(input)C57BL/6J1264.1Young adult (6 wk–6 mo)16%
RatSprague-Dawley32810.8Mature adult (6–12 mo)36%
ZebrafishAB31110.2Young adult (3–12 mo)24%

When to use

  • Designing cross-species aging studies with matched cohort ages
  • Converting cohort ages for translational papers covering multiple models
  • Reverse-looking: "What animal age matches my patient population?"
  • Comparing published results across species in literature reviews
  • Communicating cohort ages to clinical collaborators who think in human years

Do not use for

  • As a biological-age estimate — use epigenetic clocks for that
  • For genetically-modified strains with altered lifespan (progeroid, calorie-restricted)
  • For species not covered (dog, NHP, drosophila) — use species-specific tools

Cross-species comparison is only as good as the anchor points

Each species model is calibrated against published developmental milestones. The comparison is most reliable at well-studied anchor points (puberty, sexual maturity, middle age) and less reliable at extremes.

Strain factors affect lifespan position, not human-age conversion

A 12-month BALB/c mouse and a 12-month C57BL/6J mouse get the same human-equivalent age. The strain factor only adjusts where each sits on its own lifespan curve.

Zebrafish hpf assumes 28.5°C

Zebrafish development is temperature-dependent. The hpf-to-days conversion assumes standard conditions (28.5°C). Lower temperatures slow development; higher temperatures accelerate it.

Round-trip conversions are exact

Animal → human → animal conversions return the original value because all scaling models are piecewise-linear and analytically invertible.

1

Method

Each species uses a piecewise-linear function mapping animal-days to human-equivalent days. The function is defined by segments with different ratios reflecting developmental phases (rapid juvenile growth → slower adult aging). Reverse conversion analytically inverts the piecewise function. Cross-species comparison converts to human-equivalent years as a common denominator, then back-calculates to each species.

2

Validated

Last validated 2026-04-09. Calculations are designed for planning and documentation support; verify procurement decisions against manufacturer specifications or institutional SOPs.

3

How to cite

How to Cite

ConductScience Lab Animal Age Converter (v0.87.0). ConductScience, Inc. 2026. Available at: https://conductscience.com/tools/animal-age-converter

Dutta S, Sengupta P. Men and mice: Relating their ages. Life Sciences. 2016;152:244-248.

Sengupta P. The Laboratory Rat: Relating Its Age With Human's. Int J Prev Med. 2013;4(6):624-630.

Kishi S et al. The zebrafish as a vertebrate model of functional aging. Exp Gerontol. 2003;38(7):777-786.

Cross-Species Age Comparison in Translational Research

Multi-model aging studies are increasingly common, but comparing cohorts across species requires standardized age equivalence. A "middle-aged" mouse (12 months) is not the same biological age as a "middle-aged" rat (12 months) or zebrafish (18 months).

This calculator provides a common denominator — human-equivalent age — so you can design comparable cohorts across species. Enter your age in any species and see the equivalent in all others.

The Three Scaling Models

Mouse (Dutta & Sengupta 2016): Piecewise model with 6 segments. Mice age ~150× faster than humans during the first 6 weeks, slowing to ~20× past 24 months.
Rat (Sengupta 2013): Similar structure but different ratios. Rats reach puberty slightly later than mice (~6 weeks) and live ~30 months vs ~26 months.
Zebrafish (Kishi 2003 / Gerhard 2002): Zebrafish develop extremely fast (sexual maturity by 90 days) and live 3–5 years. The scaling is steepest during the embryonic and larval phases.

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