Scientific Tools

Measure grain size from metallographic micrographs using the Heyn intercept method. Upload an image, draw test lines, get your ASTM E112 grain size number.

Assign subjects to balanced treatment groups with stratification by body weight and other covariates. Full audit trail for publication and reproducibility.

Parse operant chamber output files (Med-PC, Coulbourn, Lafayette formats). Get clean CSV exports, publication-ready cumulative response curves, and AI-powered session QA.

Fit 4PL/5PL logistic models to ELISA standard curves. Interpolate unknown concentrations with QC flags for LLOQ/ULOQ, high CV, and poor recovery. Export results and publication-ready plots.

Enter colony counts from serial dilution plates. Get CFU/mL with countability flags for pour, spread, and membrane filtration methods. Full audit trail and CSV export.

Calculate viral titer (TCID50) using Reed-Muench, Spearman-Kärber, and Improved Kärber methods. Step-by-step audit trail, 95% confidence intervals, and PFU conversion.

Calculate buffer recipes with pKa-aware pH adjustment. Supports PBS, Tris, HEPES, MOPS, and more. Temperature-corrected pKa, ionic strength, and full composition tables.

Enter virus titer, cell count, and desired MOI. Get the exact inoculum volume, Poisson infection probabilities, and a step-by-step dilution protocol.

Fit 4PL or 5PL dose-response curves to compute IC50 with 95% confidence intervals. Export Hill slope, pIC50, R-squared, and publication-ready plots. Shares curve-fitting engine with ELISA tool.

Upload paired method data and get Bland-Altman plots with limits of agreement, confidence intervals, proportional bias regression, Shapiro-Wilk normality testing, and publication-ready exports. Supports difference, ratio, and percentage modes.

Calculate primer melting temperature using nearest-neighbor thermodynamics. QC checks for GC content, self-complementarity, hairpins, and primer dimers. Export one-page assay cards.

Estimate osmolarity changes when adding solutes to cell culture media. Get adjustment recipes to reach target osmolarity for mammalian cells.

Compute relative gene expression using the ΔΔCt (2^-ΔΔCt) method. Import RDML files or paste Ct values. Efficiency correction, outlier detection, and MIQE reporting checklist.

Upload plate reader time-series data and compute initial reaction rates. Automatic linear region detection, blank subtraction, and path length correction.

Calculate split ratios, seeding densities, and passage schedules for adherent and suspension cell lines. Growth curve prediction with doubling time modeling.

Validate analytical method linearity, calculate LOD and LOQ per ICH Q2(R2) guidelines. Assess precision (%RSD) and accuracy (% recovery) at each calibration level.

Plan restriction enzyme digests with 250+ enzymes from REBASE. Methylation sensitivity warnings, star activity assessment, buffer compatibility for double digests, gel simulation, and annotated linear/circular sequence maps. IUPAC degenerate base support.

Generate publication-quality annotated DNA sequence maps. Circular and linear views with restriction sites from 250+ enzymes, ORF detection across all six reading frames, custom features (GenBank-style), and primer binding site mapping. SVG and CSV export.

Design plate maps for 96-well and 384-well plates. Click to assign conditions, apply templates for standard curves and serial dilutions, export to CSV.

Calculate transfer and diluent volumes for serial dilution series. Supports fold-based (1:2, 1:10, half-log) and custom concentration targets with C1V1=C2V2.

Calculate concentration, absorbance, molar absorptivity, or path length using Beer-Lambert law (A = εlc). Includes nucleic acid A260/A280 quantification and common chromophore database.

Plot Kaplan-Meier survival curves, compute median survival with Greenwood confidence intervals, and perform log-rank tests to compare treatment groups.

Calculate molecular weight, isoelectric point, extinction coefficient, amino acid composition, charge-vs-pH curve, and GRAVY score from a protein sequence.

Count cells from hemocytometer grids. Calculate concentration, viability with trypan blue, and total cell number. Supports Neubauer, Fuchs-Rosenthal, and Bürker chambers.

Calculate sample size for t-tests, ANOVA, and proportion comparisons. Compute statistical power, generate power curves, and use Cohen's effect size conventions.

Calculate bacterial or cell doubling time from OD600 or cell count data. Two-point and time-series modes with automatic exponential phase detection.

Analyze DNA or RNA sequences: GC content, molecular weight, melting temperature, codon usage table, ORF finder, and reverse complement.

Visual teaching tool for emergency medicine that communicates CT radiation risk accurately. Compare ED imaging doses, understand evidence confidence at low doses, and explore clinical tradeoff context for common scan decisions.

Open and plot .jdx spectroscopy files — IR, NMR, and Raman spectra. Normalize, zoom, and export to CSV.

Open .wcp and .edr electrophysiology recordings from Strathclyde instruments. Browse sweeps, check scaling, export to CSV.

Open ABF and ABF2 electrophysiology files from pClamp / Axon Instruments. Browse sweeps, inspect protocol metadata, export to CSV.

View Sanger sequencing chromatograms from .ab1 files. See per-base quality scores, trim low-quality ends, export to FASTA.

Validate and repair FCS 2.0/3.0/3.1/3.2 flow cytometry files. Fix noncompliant headers and offsets, preview events, export to CSV.

Browse Nanonis .sxm and .3ds scanning probe data. View image channels, spectroscopy grids, and export to TIFF or CSV.

Open Galactic/GRAMS .spc spectral files. Plot single or multi-spectra, convert to JCAMP-DX or CSV.

View electron density map slices from MRC/CCP4 files. Browse orthogonal planes, validate MRC2014 headers, check statistics.

QC fragment analysis .fsa and .hid files. Automatic ladder sizing, peak calling, and allele table export for STR analysis.

Convert ECAT 6/7 PET images to NIfTI with BIDS sidecar generation. Automatic PHI detection and scrubbing.

Open and validate RDML files from any qPCR instrument. View amplification curves, extract Cq values, and export to CSV. Supports RDML 1.1–1.4.

Convert OME-TIFF microscopy files to OME-Zarr (v2) for cloud-native imaging. Client-side conversion with configurable chunking.

Inspect OME-TIFF microscopy file metadata without opening the image. View channels, dimensions, physical sizes, instrument settings, and structured annotations.

Open NeuroExplorer .nex and .nex5 files without NeuroExplorer software. View neurons, events, intervals, waveforms, and continuous data with spike raster previews.

Validate Neurodata Without Borders (.nwb) file metadata. Check required fields, NWB schema compliance, and DANDI archive readiness.

Compute sensitivity, specificity, PPV, NPV, likelihood ratios, DOR, and Shannon entropy from a 2×2 contingency table. Three input modes with Wilson or Clopper-Pearson CIs.

Interactive Fagan nomogram for Bayesian post-test probability. Enter pretest probability and likelihood ratio to visualize the diagnostic update.

Upload CSV data to generate ROC curves, compute AUC with confidence intervals, and find the optimal threshold by Youden index.

Compute odds ratio, relative risk, absolute risk reduction, and NNT from a 2×2 table. Study-design-aware with automatic OR≠RR warnings.

Buderer's formula for diagnostic accuracy studies. Compute required sample size from expected sensitivity, specificity, prevalence, and desired CI width.

Passing-Bablok and Deming regression with Bland-Altman companion plot. Upload paired CSV data for complete method comparison analysis.

Welch's t-test with Cohen's d and Pearson correlation with Fisher z CI. Enter raw data or summary statistics for instant results.

Upload a micrograph and estimate porosity using Otsu thresholding. Calculate area fraction, pore count, and export thresholded images.

Scan CSV, TSV, JSON, or text files for personally identifiable information (PII). Detect emails, phone numbers, SSNs, and other identifiers before data sharing.

Check CSV files against tidy data principles (Wickham 2014). Detect wide-format patterns, mixed types, duplicates, and naming issues.

Enter filament response sequences and compute Dixon 50% withdrawal thresholds. Supports mouse and rat filament sets with automatic up-down progression, confidence intervals, and group comparison.

Compute %PPI per prepulse intensity, habituation indices, and intensity-response curves. Includes drosophila light-off startle mode with time-series CSV, automatic startle detection, and habituation curve fitting.

Configure TTL synchronization between behavioral tracking software and electrophysiology, calcium imaging, or optogenetics systems. Generates wiring checklists and test procedures.

Score novel object recognition with a live keyboard scoring pad or enter pre-timed exploration totals. Computes Discrimination Index (DI), Preference Index (PI), and group comparisons with error bars.

Upload XY tracking data or per-trial summaries. Compute escape latency curves, quadrant analysis, probe trial heatmaps, swim path visualization, Gallagher proximity, and search strategy classification.

Enter hole visit sequences or upload tracking data. Compute primary/total errors, search strategy classification (direct, serial, random per Bhatt et al.), and learning curves with radial hole visualization.

Upload XY tracking data from rodent or zebrafish experiments and compute total distance, velocity, center vs periphery time, thigmotaxis index, center entries, path trace overlay, and time-bin habituation analysis. Includes zebrafish well plate presets.

Upload Y-coordinate tracking data from zebrafish novel tank diving tests. Compute bottom time percentage, latency to top zone, top-bottom transitions, freezing episodes, vertical position heatmap, and time-binned habituation curves with group comparisons.

Enter chamber times and interaction zone durations. Compute Sociability Index, Social Novelty Index, preference scores, and counterbalance validation with group comparisons.

Enter arm times and entries per animal. Compute Anxiety Index, % open arm time, % open arm entries, total entries (locomotion proxy), and group comparisons with error bars.

Upload velocity traces or enter pre-scored freezing data. Compute % freezing per epoch (baseline, CS, ITI, context, cued), freezing bout analysis, and session time courses.

Enter latency-to-fall data across training days. Compute learning curves, AUC comparison, group statistics, RPM at fall for accelerating protocols, and publication-ready plots.

Enter immobility, swimming, and climbing durations per animal. Get % immobility, behavior proportions, time-bin breakdown, latency to first immobility, and group comparisons.

Enter immobility durations per animal. Get % immobility, latency to first immobility, time-bin analysis, and group comparisons with error bars.

Enter time in light/dark compartments or upload multiwell batch CSV. Get % time in light, transition frequency, per-phase metrics, treatment mapping, dose-response, QC flags, and group comparisons.

Enter arm entry sequences per trial. Classify working memory errors (re-entries to baited arms) and reference memory errors (entries to never-baited arms) with learning curves.

Enter arm entry sequences or upload CSV. Compute % spontaneous alternation, tetragram frequency analysis, Shannon entropy, turn bias, total arm entries, same-arm returns, and comparison to 50% chance level with group statistics.

Enter per-trial choices and rewarded side schedule. Get % correct per block, learning curves, trials to criterion, and reversal learning analysis with group comparisons.

Enter tubing dimensions, fluid viscosity, and flow rate. Compute pressure drop via Hagen-Poiseuille, Reynolds number, required pump force, and reverse-mode max flow rate. Printable reference sheet and CSV export.

Enter animal weight, drug concentration, and target dose rate. Compute pump rate (µL/min, mL/hr), total volume, drug requirements with 20% overage, and blood volume safety check. Supports multi-step dose ramp scheduling.

Enter flow rate, collection interval, and probe specs. Get a complete fraction collection schedule with dead volume delay, evaporation risk check, timeline visualization, and printable bench sheet.

Skull tilt correction from bregma-lambda Z-heights, DV adjustment, bilateral symmetry check, SVG skull schematic, printable surgery plan, and interactive coronal atlas plate viewer with coordinate-to-region mapping and injection spread visualization.

Calculate field of view, resolution, Nyquist frame rate, and estimated neuron yield for calcium imaging setups.

Convert activity time-series CSV into sleep/wake epochs. Computes bout metrics, actograms, sleep profiles, day/night split, and group comparisons for Drosophila sleep research.

Enter baseline and post-treatment latencies for hot plate, tail flick, or Hargreaves assays. Compute %MPE with cutoff enforcement, group comparisons with SEM, time-course analysis, AUC, and ED50 prep export.

Score forced swim test or tail suspension test behavior in real-time with keyboard shortcuts. Get immobility %, latency, bout analysis, time-bin breakdown, group comparisons, and Cohen's kappa inter-rater reliability.

Calculate tricaine methanesulfonate (MS-222) working solutions for zebrafish sedation, anesthesia, and euthanasia. Computes powder and stock dilution recipes with sodium bicarbonate buffering.

Convert hours post-fertilization and incubation temperature to developmental stage using Kimmel et al. (1995) staging series. Temperature correction for 20–33°C.

Calculate unionized ammonia (NH₃) from total ammonia nitrogen (TAN), pH, temperature, and salinity. 4-tier risk assessment with corrective action recommendations for aquatic facilities.

Plan conductivity adjustments for aquatic systems. Calculate salt stock dosing volume, pump runtime, and stepwise dosing schedule with unit conversion (µS/cm, mS/cm, ppt).

Calculate recirculating rack system turnover rate, per-tank flow, and daily water exchange volume. Includes pump derate factor and commissioning checklist for aquatic facilities.

Calculate how many breeding pairs you need to produce a target number of embryos within a given timeline. Models spawning success, fertilization rate, and recovery period.

Calculate how many eggs to collect and breeding pairs to set up for your zebrafish experiment endpoint. Models stage-by-stage attrition from fertilization to target dpf.

Generate a customizable water quality monitoring SOP for zebrafish facilities. Includes daily, weekly, and monthly checklists, parameter reference table, and downloadable CSV log template.

Calculate zebrafish stocking density and check compliance against EU/IACUC guidelines for larvae, juvenile, and adult fish. Color-coded status with redistribution recommendations.

Calculate dissolved oxygen saturation at given temperature, salinity, and altitude using the USGS Benson & Krause (1984) standard. Compare measured DO to saturation with species-specific hypoxia thresholds.

Model how drug or contaminant concentration decreases over successive partial water changes. Forward and inverse solve modes with decay curve chart and full schedule table.

Convert calcium and magnesium ion concentrations to total water hardness as CaCO₃. Classify hardness (Soft to Very Hard) and check species-specific suitability for zebrafish, freshwater, cichlids, or marine.

Calculate water volume for laboratory aquarium tanks from dimensions. Includes presets for common zebrafish facility tanks (1.8 L, 3 L, 6 L) and a stocking density compliance checker.

Paste a language sample and get Mean Length of Utterance in morphemes and words, total utterances, total morphemes, and the matching Brown's stage. Implements Brown (1973) morpheme counting rules and runs entirely in your browser.

Interactive reference for Brown's (1973) five stages of grammatical development. Look up a stage by child age or MLU, see the MLU range, acquired morphemes, example utterances, and clinical milestones for each stage.

Paste a language sample and get type-token ratio (TTR), number of different words in the first 100 tokens (NDW-100, Miller 1981), and NDW per 50 utterances (NDW-50, SUGAR). Implements the standard SALT/SUGAR tokenisation rules and runs entirely in your browser.

Paste a language sample, get total utterances, total clauses (main + subordinate), and the clauses-per-utterance ratio. Subordinate clauses are detected with a heuristic over standard English subordinators (because, when, while, that, who, which, …). Reports the developmental band against Loban (1976) and Nippold (2009) reference values. Runs entirely in your browser.

Free Brown's 14 grammatical morphemes inventory tracker for speech-language pathologists. Tick off each morpheme as you observe it in a language sample, see live progress against the canonical acquisition order, identify the first un-mastered Brown stage, and export a one-page PDF summary for the chart. Implements Brown (1973) and Miller & Chapman (1981).

Paste a language sample, tap G or U per utterance, and get Percent Grammatical Utterances (PGU) live. Returns the Eisenberg & Guo (2013) severity band (typical / borderline / clinical concern) once at least 25 utterances are scored. Mobile-friendly scoring table, client-side, no sign-up.

Free printable and fillable language sample analysis worksheet for speech-language pathologists. Five columns (utterance #, transcription, morpheme count, grammatical Y/N, notes), configurable row count up to 100 utterances, browser print produces a clean PDF, and an inline running summary tracks total utterances, total morphemes, and rolling MLU as you fill it in.

Free Developmental Sentence Scoring (DSS) calculator for speech-language pathologists. Paste 50 sentences, tap weighted points across the eight Lee (1974) grammatical categories — Indefinite Pronouns, Personal Pronouns, Main Verbs, Secondary Verbs, Negatives, Conjunctions, Interrogative Reversals, Wh-Questions — plus the all-correct sentence point, and the calculator returns the live DSS with a per-category breakdown. Mobile-friendly tap-through grid, client-side, no sign-up.

Free Index of Productive Syntax (IPSyn) calculator for speech-language pathologists. Score the 56 Scarborough (1990) grammatical items across the Noun Phrase, Verb Phrase, Question/Negation, and Sentence Structure subscales from a 100-utterance language sample. Live IPSyn total, per-subscale subtotals, sample-size guard, mobile-friendly, client-side, no sign-up.

Free interactive speech sound development chart for speech-language pathologists. Look up the age of acquisition for the 24 English consonants based on the McLeod & Crowe (2018) cross-linguistic systematic review. Filter by age band and word position (initial, medial, final), enter a child age and instantly see which sounds are age-expected versus still developing. Mobile-friendly, client-side, no sign-up.

Free interactive phonological process identifier for speech-language pathologists. Enter a target word and the child production and the calculator flags every matching process from the twelve most common English patterns (cluster reduction, fronting, stopping, gliding, vocalisation, weak syllable deletion, final consonant deletion, deaffrication, denasalisation, prevocalic voicing, devoicing, initial consonant deletion), each tagged with its Bowen (2015) age of suppression so you can see whether the production is age-expected or persistent. Mobile-friendly, client-side, no sign-up.

Free interactive articulation screener for speech-language pathologists. Tick errored sounds on a 30-word single-word probe covering every English consonant in at least one word position (initial, medial, final). The tool lists every errored sound, groups errors by position, and flags whether each sound is age-expected or past its McLeod & Crowe (2018) age of mastery — headline pass / at-cusp / refer decision in one keystroke. Modelled on the Goldman-Fristoe Test of Articulation 3 sounds-in-words structure and the Iowa-Nebraska norms (Smit et al. 1990). Mobile-friendly, client-side, no sign-up.

Free interactive speech intelligibility calculator for speech-language pathologists. Enter a child age and the observed unfamiliar-listener intelligibility percent from a connected-speech sample, and the tool returns the typical / borderline / refer flag against the pooled Coplan & Gleason (1988), Flipsen (2006), and Hustad et al (2021) age expectations. Built for SLP intake, well-child visits, EI eligibility, and parent counselling. Mobile-friendly, client-side, no sign-up.

Free interactive Percent Consonants Correct (PCC) calculator for speech-language pathologists. Enter the consonants attempted and produced correctly from a 50- to 100-utterance connected-speech sample and get the PCC percent plus the Shriberg & Kwiatkowski (1982) severity band (mild, mild-moderate, moderate-severe, severe). Built for SLP intake, IEP eligibility, treatment-progress tracking, and graduate phonological-assessment training. Mobile-friendly, client-side, no sign-up.

Free interactive Voice Handicap Index-10 (VHI-10) calculator for speech-language pathologists, otolaryngologists, and voice clinics. Score the 10-item Rosen et al. (2004) patient self-report instrument and get the total (0 - 40), the Arffa et al. (2012) clinical severity band (normal, mild, moderate, severe), and per-domain subtotals (Functional, Physical, Emotional). Built for SLP voice intake, otolaryngology clinics, occupational voice screening, pre / post phonosurgery comparison, and graduate voice-evaluation training. Mobile-friendly, client-side, no sign-up.

Free interactive Eating Assessment Tool-10 (EAT-10) calculator for speech-language pathologists, otolaryngologists, gastroenterologists, and dysphagia clinics. Score the 10-item Belafsky et al. (2008) patient self-report instrument and get the total (0 - 40), the ≥ 3 abnormality flag, and a descriptive severity band (normal, mild, moderate, severe). Built for SLP and ENT dysphagia intake, voice clinic co-screening, head-and-neck cancer surveillance, stroke rehabilitation, neurodegenerative disease caseloads, older-adult home-health, and graduate dysphagia-assessment training. Mobile-friendly, client-side, no sign-up.

Free interactive reading grade level analyzer for speech-language pathologists, school psychologists, audiologists, and rehabilitation clinicians. Paste a clinical report, parent handout, IEP summary, or informed-consent document and get Flesch-Kincaid Grade Level, SMOG, Gunning Fog, Flesch Reading Ease, average sentence length, and a consensus grade classified against the AMA / NIH / CDC parent-readability target of grade 6 or below. Built for SLP report writing, IEP documentation, school and medical discharge planning, informed-consent review, and graduate clinical-writing training. Mobile-friendly, client-side, no sign-up.

Free interactive caseload workload calculator for school-based speech-language pathologists implementing the ASHA Workload Approach (ASHA 2002 Workload Analysis Technical Report; ASHA 2024 School-Based Service Delivery Practice Portal). Enter the number of students on your caseload by service intensity tier (consult, mild 30-60 min/week, moderate 60-90, severe 90-150, profound 120-240), plus annual counts of initial, triennial, and dismissal evaluations, IEP / IFSP / 504 meetings, parent conferences, and weekly travel, supervision, and professional-development minutes, and the calculator returns the total weekly workload in hours, a breakdown across seven ASHA workload categories (direct service, indirect documentation, evaluations, meetings, travel, supervision, PD), and a capacity flag (under, ok, at-capacity, over) against the 37.5-hour FTE baseline. Built for school SLPs, special-education coordinators, district SLP leads, CF-SLPs, and state school SLP association advocacy. Mobile-friendly, client-side, no sign-up.

Free interactive story grammar scorer implementing the Stein & Glenn (1979) 6-element checklist (setting, character, initiating event, attempt, consequence, reaction) for school-based and clinic speech-language pathologists screening paediatric narrative language samples. Tick each present element, the scorer counts the elements (0-6), classifies the result as incomplete (0-2), partial (3-4), or complete (5-6), and lists the missing elements as suggested intervention targets with rationales drawn from the Petersen & Spencer (2016) clinical tutorial. Designed as a fast 2-5 minute triage tool before a full Narrative Scoring Scheme (NSS) rating. Built for school SLPs, clinic SLPs, early-intervention teams, graduate SLP students, and paediatric language researchers. Mobile-friendly, client-side, no sign-up.

Free interactive conversation turn analyzer for school-based and clinic speech-language pathologists analysing child-partner dialogue transcripts. Paste a transcript with speaker tags (e.g. C: and P:) and mark each child turn as [on] or [off] for topic maintenance. The analyzer returns turns per speaker, average turn length, longest / shortest turn, total speaker-to-speaker turn switches, the child topic-maintenance ratio, a four-tier topic-maintenance classification (poor, emerging, adequate, strong), and a three-tier turn-balance classification (partner-dominant, balanced, child-dominant) in under five minutes. Tier thresholds are derived from Fey (1986), Brinton & Fujiki (1989), Mentis & Prutting (1991), and Timler (2008). Built for school SLPs, clinic SLPs, autism-assessment teams, graduate SLP students, and paediatric language researchers screening pragmatic-discourse in children with DLD, ASD, ADHD, and TBI. Mobile-friendly, client-side, no sign-up.

Free interactive Narrative Scoring Scheme (NSS) calculator implementing the Heilmann, Miller, Nockerts, & Dunaway (2010) rubric for school-based and clinic speech-language pathologists scoring paediatric narrative language samples. Rate each of the seven NSS subscales (introduction, character development, mental states, referencing, conflict resolution, cohesion, conclusion) from 0 (immature / absent) to 5 (proficient) based on the child's story retell or personal narrative, and the calculator sums the subscale scores, classifies the total out of 35 against the published 5-11-year-old story-retell expectation band (15-28 of 35), and returns up to three intervention targets derived from the lowest-scoring subscales. Built for school SLPs, clinic SLPs, early-intervention teams, graduate SLP students, and paediatric language researchers. Mobile-friendly, client-side, no sign-up.

Free interactive therapy frequency recommender for school-based speech-language pathologists, clinic SLPs, early interventionists, and IEP / IFSP / plan-of-care teams. Pick the severity of the communication disorder (mild, moderate, severe, profound), the age band (birth-3, 3-5, 5-11, 11-18), and the service setting (school-based IEP, clinic / private practice, early intervention IFSP) and the tool returns an evidence-based recommended total service minutes per week, sessions per week, typical session length, a recommended service-delivery model (individual pull-out, small-group pull-out, classroom push-in, consultation, home visit), an evidence summary with citations to the ASHA School-Based Service Delivery Practice Portal (2024), Cirrin et al. (2010) systematic review, Brandel & Loeb (2011) national SLP survey, and Warren et al. (2007) dose-response review, and severity-specific clinical caveats. Mobile-friendly, client-side, no sign-up.

Free interactive IEP (Individualised Education Programme) goal generator for school-based speech-language pathologists, special-education teachers, and IEP teams. Pick the goal area (one of the eight ASHA School-Based Service Delivery areas: articulation, expressive language, receptive language, fluency, voice, pragmatics / social communication, AAC, literacy), pick the target skill from the curated bank of 30+ starter skills, enter the baseline percent and the target percent, set the consecutive-sessions mastery criterion and the annual-review deadline, and the tool drafts a SMART (Specific, Measurable, Achievable, Relevant, Time-bound) IEP goal sentence ready to paste into the IEP. Includes a SMART self-check rubric, a customisable condition clause, a copy-to-clipboard button, and suggested baseline / target ranges that match published school-age SLP intervention practice. Mobile-friendly, client-side, no sign-up.

Free interactive Early Intervention (IDEA Part C) eligibility calculator for paediatricians, family-resource coordinators, early interventionists, school-based speech-language pathologists, NICU follow-up clinics, and parents. Enter the child's chronological age and a single performance value (percent delay, standard score on a norm-referenced test, or developmental age in months) and the tool checks the child against the four canonical state Part C eligibility rule families published in the Early Childhood Technical Assistance Center (ECTA 2015) state summary: 25 % delay in one developmental domain, 33 % delay in one domain, 50 % delay in one domain, 1.5 SD below the mean (standard score ≤ 78), and 2.0 SD below the mean (standard score ≤ 70). Returns Meets / Borderline / Does not meet for each rule along with the margin from the published cut and example states using each rule. Mobile-friendly, client-side, no sign-up.

Free interactive speech-language milestones checker for children from birth to 72 months (6 years). Enter the child's age in months and tick the receptive (understanding) and expressive (use) communication milestones they have met. The tool classifies the current age band as on track, monitor, or refer for evaluation against the ASHA communication milestones (2024), the CDC "Learn the Signs. Act Early." revised milestones (Zubler et al. 2022 Pediatrics), the Bright Futures 4th ed. well-child developmental surveillance schedule, and the Ages & Stages Questionnaires 3rd ed. Built for paediatricians, early interventionists, school-based SLPs, developmental paediatricians, Head Start teachers, and parents. Mobile-friendly, client-side, no sign-up.

Free interactive CAPE-V (Consensus Auditory-Perceptual Evaluation of Voice) rating tool for speech-language pathologists, voice clinic laryngologists, and voice-therapy trainees. Rate the six perceptual parameters — Overall Severity, Roughness, Breathiness, Strain, Pitch, and Loudness — on the 100 mm visual analog scale as published by Kempster et al. (2009) and get instant severity classification (within normal limits, mild MI, moderate MO, severe SE) anchored to the Kempster printed-form bands. Built for voice clinic intake, voice therapy progress visits, pre- and post-laryngology surgical follow-up, and SLP graduate training in voice evaluation. Mobile-friendly, client-side, no sign-up.

Free interactive percent syllables stuttered (%SS) calculator for speech-language pathologists. Enter stuttered syllables and total syllables from a 300- to 600-syllable conversational speech sample and get the %SS plus the Guitar (2019) clinical severity band (not stuttering, mild, moderate, severe). Built for SLP fluency intake, IEP eligibility, preschool stuttering screening, treatment-progress tracking, and graduate fluency-assessment training. Mobile-friendly, client-side, no sign-up.

Interactive lookup for SUGAR (Pavelko & Owens 2017) language sample normative values. Enter the child's age in years and months and the tool returns the matching MLU, TNW, CPS, and MLUL means with ±1 SD typical ranges plus the full SUGAR table for context. Built for speech-language pathologists running 50-utterance samples.

Plan mouse colony cage demand against NIH Guide Table 3.2 housing density. Multi-strain census, facility utilization alerts, monthly growth-rate forecast, CSV export.

Project mouse colony per-diem and study housing costs. Multi-line cage entry, institutional rate defaults (academic / biotech / GLP), monthly burn, cost-per-data-point, CSV export.

Universal animal-to-human age converter for mouse, rat, and zebrafish. Cross-species comparison, bidirectional conversion, strain-specific lifespan factors, life-stage classification.

Convert mouse age to human-equivalent age using Dutta & Sengupta (2016) piecewise scaling. Strain-specific lifespan factors, life-stage classification, CSV export.

Convert rat age to human-equivalent age using Sengupta (2013) piecewise scaling. Strain-specific lifespan factors for Sprague-Dawley, Wistar, Fischer 344, and more.

Convert zebrafish age to human-equivalent age using Kishi (2003) / Gerhard (2002) scaling. Strain-specific lifespan factors, hpf to dpf staging, life-stage classification.

Compute injection volume from body weight, dose, and stock concentration. Diehl et al. (2001) good-practice route limits, impractical-draw alerts, cohort stock projections, CSV export.

Convert mouse, rat, and human doses with the Reagan-Shaw et al. (2008) FASEB J body-surface-area method. Canonical Km factors, cross-species comparison table, and CSV export. Free, client-side.

Generate printable 3.5 × 5 in cage cards with embedded QR codes for mouse and rat colonies. Bulk CSV import, NIH-compliant fields, duplicate detection, versioned QR JSON payload. Free, client-side.

Compute rat housing and per-diem costs using NIH Guide (8th ed.) Table 3.3 floor area requirements. Cage counts, density compliance, monthly burn, CSV export. Free, client-side.

Plan rat injection volumes from body weight, dose, and stock concentration. Strain presets for Sprague-Dawley, Wistar, Long-Evans, F344. Diehl et al. (2001) rat route limits, cohort stock projections, CSV export.

Estimate total worms per C. elegans plate from a visual density preset or an ROI count. Classifies plate density against the WormBook starvation threshold and warns when chunking is overdue.

Scale alkaline hypochlorite bleach reagents for any number of gravid C. elegans plates and predict L1 → young adult stage pickups at 15, 20, or 25 °C with wall-clock ETAs.

Scale the WormBook S-buffer freezing solution recipe for any number of C. elegans cryovials, recommend recovery test plates, and output the slow-cool freezedown protocol.

Compute OP50 culture and LB volumes for any combination of 35/60/100 mm NGM plates with custom seeding volumes and HT115 RNAi feeder substitution.

Test observed offspring counts against expected Mendelian ratios for monohybrid, dihybrid, test cross, incomplete dominance, or any custom ratio with chi-square goodness-of-fit and full p-value.

Compute how many breeding trios, dams, and cages you need to deliver a target weanling count, accounting for genotype frequency, strain wean rate, genotyping success, and a 25% breeding-failure buffer.

Recommend the optimal DNA ladder, compute loading-dye volumes, estimate gel run time, and generate a well layout for 8/16/24/48-well mini and midi gels. Flags well-capacity overflows and agarose-concentration mismatches.

Compute per-reaction and scaled master-mix volumes for Taq PCR from stock/final concentrations. Flags sub-0.5 µL pipetting precision issues, generates a bench-ready protocol with component addition order, and exports CSV.

Scale DirectPCR (Viagen), NaOH/Tris hot-shot (Truett 2000), and proteinase K + standard lysis buffer recipes for any mouse genotyping batch. Outputs master-mix volumes, 96-well plate layout, validation warnings, and a bench-ready protocol summary.

Compute Wright's coefficient of relatedness (r) and the offspring inbreeding coefficient (F) for common pedigree relationships. Flags matings that cross the first-cousin threshold (F > 0.0625), with an inbred-strain override for C57BL/6J and similar lines.

Compare the multi-year cost of keeping mouse lines live vs. cryopreserving (embryo or sperm) and recovering only the lines that get used. Reports break-even year, recommendation, year-by-year cost curve, and CSV export.

Project month-by-month mouse colony growth from a small founder population using a discrete-time generation simulation. Reports generations to target, peak cage count, and an 18-month colony curve, with optional facility cap.

Compute how many backcross generations and how many months it takes to reach a target recipient genome proportion (e.g., 99% or 99.9%) — with or without marker-assisted speed congenic (Markel 1997).

Log anesthesia events and classify cumulative CO₂ exposure for a Drosophila cohort. Bartholomew (2015) thresholds, behavioral assay confound flag, recommended recovery period, CSV export.