Mouse Age Converter

Dutta & Sengupta (2016) Mouse-Human Age Scaling

The piecewise model used by the calculator:

• Days 1–21 (pre-weaning): ~150 human days per mouse day
• Days 21–42 (juvenile, weeks 3–6): ~150 human days per mouse day
• Days 42–180 (young/mature adult, months 1.5–6): ~45 human days per mouse day
• Days 180–365 (middle age, months 6–12): ~30 human days per mouse day
• Days 365–730 (aged, months 12–24): ~25 human days per mouse day
• Days >730 (senescent): ~20 human days per mouse day

The published model anchors mouse adulthood (~3 months) to human age 20, mouse middle age (~12 months) to human age 38, and mouse senescence (~24 months) to human age 60 — the calculator reproduces these landmarks exactly.

Why Age Matters in Translational Studies

Most preclinical studies use 8–12 week old mice, which corresponds to a human age of ~18–22 — a window almost no human disease cohort represents. This is one of the reasons preclinical-to-clinical translation often fails for aging-related conditions.

For aging research, the recommended cohorts are:

• Young adult: 3–6 months (~22–34 human years)
• Middle-aged: 12–14 months (~38–47 human years)
• Aged: 18–24 months (~56–69 human years)

Use this calculator to label your cohorts in human-equivalent terms when writing methods sections — it dramatically improves clinical reviewers' interpretation.