What does the 5-CSRTT measure?

The 5-choice serial reaction time task measures visuospatial attention, response control, omissions, premature responding, perseveration, and latency in rodent operant chambers.

What standard parameters are common?

Many protocols use brief stimulus durations around 0.5 to 1 s and an intertrial interval around 5 s after training. Challenge sessions often shorten stimulus duration or lengthen the ITI.

What does accuracy mean?

Accuracy reflects attention among trials with a response. It is correct responses divided by correct plus incorrect responses, multiplied by 100.

What do premature responses measure?

Premature responses are nose pokes before stimulus onset and are commonly interpreted as an impulsivity endpoint, especially in variable-ITI challenge sessions.

What do perseverative responses measure?

Perseverative responses are repeated responses after a correct response and reward delivery. They are often treated as a compulsivity or response-control endpoint.

How are training stages usually handled?

Animals progress from shaping and long stimulus durations to baseline performance. Challenge stages may reduce stimulus duration, vary ITI, or add pharmacological manipulations.

Can this parse raw Med-PC files?

This page analyzes extracted session summaries. Use the Operant Session Analyzer first for raw Med-PC parsing, then paste the extracted 5-CSRTT summary values here.

ToolsConductScience tool

AccuracyFree in-browser calculator

5-CSRTT Analyzer.

Name: 5-CSRTT Analyzer
Author: ConductScience

Compute accuracy, omissions, premature responses, perseverative counts, latency summaries, group SEM, and CSV export.

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Validated2026-04-30

CitableMethods and citation included

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Have a Med-PC file?

Use the Operant Session Analyzer first to parse raw chamber exports, then paste the extracted 5-CSRTT session summaries here.

Open Operant Session Analyzer

5-CSRTT session table

Enter extracted session summaries. Accuracy uses correct divided by correct plus incorrect responses. Omissions and premature responses use total trials.

Accuracy %	Omission %	Premature %
86.7%	10.0%	7.0%
81.4%	14.0%	10.0%
77.5%	20.0%	14.0%
68.6%	30.0%	18.0%

Accuracy

Omissions

Premature responses

Accuracy learning curve

When to use

Analyze already-extracted 5-CSRTT session summaries
Compute accuracy, omission, and premature response percentages
Track perseverative response counts and latency columns
Compare group means with SEM across sessions
Bridge Med-PC parsing from the Operant Session Analyzer

Do not use for

Raw Med-PC file parsing without summary extraction
Free-operant FR or PR schedules
Video-based five-hole scoring without operant event logs

Accuracy excludes omissions

Accuracy uses correct divided by correct plus incorrect responses. Omissions are a separate endpoint and should not be added to the response denominator.

Premature responding depends on ITI design

Variable or extended ITI challenges can increase sensitivity to impulsivity. Report ITI parameters alongside premature response percentages.

Latency helps interpret omissions

Long correct-response or reward-collection latency can suggest motor, motivational, or reward-access issues that complicate attention interpretation.

Resources

Stimulus duration and ITI recorded for each session
Correct and incorrect response counts separated
Omissions normalized to total trials
Premature responses normalized to total trials
Perseverative responses retained as counts
Latency columns reviewed for motor or motivation confounds

Method

Accuracy percent is correct divided by correct plus incorrect responses. Omission percent is omissions divided by total trials. Premature percent is premature responses divided by total trials. Group SEM uses sample standard deviation divided by square root of n.

Validated

Last validated 2026-04-30. Calculations are designed for planning and documentation support; verify procurement decisions against manufacturer specifications or institutional SOPs.

How to cite

How to Cite

ConductScience 5-CSRTT Analyzer (v1.0). ConductScience, Inc. 2026. Available at: https://conductscience.com/tools/five-csrtt-analyzer

This tool performs descriptive calculations from user-entered 5-CSRTT summaries. It does not replace protocol-specific statistics, exclusion criteria, or raw event verification.

5-CSRTT Overview

The 5-choice serial reaction time task is a rodent analogue of continuous performance testing. Animals monitor five apertures, respond to brief visual cues, and receive reward for correct responses.

This analyzer focuses on already-extracted session summaries so labs can compare accuracy, omissions, premature responses, perseverative responding, and latency across groups.

Metrics and Math

Accuracy percent equals correct responses divided by correct plus incorrect responses, multiplied by 100. Omission percent equals omissions divided by total trials. Premature percent equals premature responses divided by total trials.

Perseverative responses are reported as counts because many protocols treat them as event totals rather than a denominator-normalized percentage.

Interpretation

Lower accuracy can indicate attentional impairment, but it should be interpreted with omissions and latencies. High omissions can indicate disengagement, sedation, or sensory issues. High premature responding is commonly used as an impulsivity signal.

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