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IACUC & ComplianceFree in-browser calculator

IACUC Protocol Expiration Tracker.

Compute your protocol expiration date, continuing review milestones, and a multi-tier alert schedule. Color-coded status shows green, yellow, red, or expired at a glance.

PrivateData stays in your browser
LiveNo sign-up required
Validated2026-04-07
CitableMethods and citation included

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Load example IACUC protocol expiration tracker data to see the full workflow

Protocol Details

Required fields
  • Protocol number is required.
  • Approval date must be a valid date (YYYY-MM-DD).

When to use

  • Tracking expiration and continuing review dates for one or more IACUC protocols
  • Setting up a reminder schedule to avoid missed renewals
  • Onboarding new lab members and showing them when protocols are due
  • Preparing for AAALAC site visits — demonstrating proactive compliance tracking
  • Generating a CSV timeline for administrative reporting

Do not use for

  • As a substitute for your institution's official IACUC management system (e.g., Click, IRBManager)
  • For IBC (Institutional Biosafety Committee) or IRB protocol tracking — different review cycles
  • To calculate whether an amendment extends the term — it does not

Start the renewal clock at 90 days, not 30

Most IACUC offices need 4-6 weeks of processing time after you submit. If you start preparing at 30 days, a single round of reviewer questions can push you past the deadline. The tracker's 90-day alert is your "start writing" signal.

Track the approval date, not the submission date

The 3-year term and annual review cycle are measured from the date the IACUC voted to approve (or the DMR signed off), not the date you submitted the application. These can differ by weeks or months.

Amendments do not reset the clock

A common misconception: filing a major amendment does not extend the protocol term. If your protocol was approved in June 2024, it expires in June 2027 regardless of amendments. Plan de novo submissions accordingly.

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Method

Computes protocol expiration as approval date + term length (1-3 years). Generates continuing review milestones at the specified interval (default: 12 months). For each milestone, produces alerts at 90, 60, 30, and 14 days before the date. Status is color-coded: green (>60 days), yellow (14-60 days), red (<14 days), expired (<0 days). Amendments are noted but do not modify the expiration date, per PHS Policy. All computation is client-side.

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Validated

Last validated 2026-04-07. Calculations are designed for planning and documentation support; verify procurement decisions against manufacturer specifications or institutional SOPs.

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How to cite

How to Cite

ConductScience IACUC Protocol Expiration Tracker (v1.10.0). ConductScience, Inc. 2026. Available at: https://conductscience.com/tools/iacuc-protocol-expiration-tracker

Office of Laboratory Animal Welfare. PHS Policy on Humane Care and Use of Laboratory Animals. Bethesda, MD: NIH; 2015.

USDA APHIS. Animal Welfare Act and Animal Welfare Regulations. 9 CFR Parts 1-4. Washington, DC: US Government Publishing Office; 2023.

The IACUC protocol lifecycle

From approval to renewal

An IACUC protocol follows a predictable lifecycle: initial full committee review (or designated member review for lower-risk studies) → approval → continuing reviews at annual intervals → expiration after the maximum term (typically 3 years) → de novo submission for renewal.

  • Approval date: when the full committee (or DMR) approved the protocol
  • Continuing review dates: annual anniversaries of the approval date
  • Expiration date: approval date + term length (usually 3 years)
  • Submission deadlines: typically 60-90 days before each review date to allow for IACUC processing

The PHS Policy (IV.C.1-5) and Animal Welfare Act Regulations (§2.31) mandate these review cycles. AAALAC also evaluates institutional compliance with protocol review timelines during accreditation site visits.

Common protocol expiration pitfalls

Assuming amendments extend the term

This is the #1 mistake. No matter how many amendments are approved, the original expiration date does not change. A major amendment filed in year 2 still leaves only 1 year on the original 3-year clock.

Late continuing review submission

Submitting a continuing review the week before it is due almost guarantees a lapse. IACUCs need time for administrative review, potential questions, and committee scheduling. Start the continuing review 90 days early and submit 60 days before the due date.

Losing track of multiple protocols

PIs running 3-5 protocols with staggered approval dates frequently miss deadlines. A centralized tracker — whether this free tool or ConductColony — prevents oversight.

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