MRI Sequence Parameter Fundamentals
MRI acquisition parameters control three interdependent properties: image quality, scan time, and patient safety.
Calculate scan time, resolution, SNR, and SAR for MRI pulse sequences with clinical and research presets.
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MRI acquisition parameters control three interdependent properties: image quality, scan time, and patient safety.
Several factors can compromise MRI protocol quality:
• SAR limits at 3T: Spin-echo sequences with 180° refocusing pulses may exceed SAR limits at short TR. Use variable flip angle refocusing or lower parallel factors • Partial volume effects: Thick slices (>5 mm) mix signals from different tissues, reducing diagnostic sensitivity for small lesions • Motion artifacts in long scans: Scan times >8 minutes significantly increase motion artifact risk. Consider parallel imaging or partial Fourier to reduce time • EPI distortion: fMRI and DWI use EPI readouts that are sensitive to B0 inhomogeneity, causing geometric distortion near air-tissue interfaces • Parallel imaging noise: GRAPPA/SENSE acceleration >3 introduces significant g-factor noise penalty. Acceleration of 2 is the typical sweet spot • Inadequate averages: Single average (NEX=1) may be insufficient for small-FOV or high-resolution protocols. SNR increases with sqrt(NEX) but scan time increases linearly