Childhood Cancer Survivor Study

The Childhood Cancer Survivor Study (CCSS), a component of the Long-Term Follow Up Study that began in 1994 and was funded by a grant from the National Cancer Institute, includes all participants with a confirmed diagnosis of cancer and 5 year survival, a cohort of 35,923 childhood cancer survivors diagnosed between 1970 and 1999. It also includes over 5,000 siblings of survivors who serve as the comparison group for the study. The CCSS cohort has been assembled through the efforts of 31 participating centers in the United States and Canada. CCSS is a resource in which to investigate current and future questions regarding consequences of therapy, genetic associations, disease processes and causation, interventions, and quality of life among childhood cancer survivors. The Childhood Cancer Survivor Study (CCSS) includes all participants with a confirmed diagnosis of cancer and 5 year survival, a cohort of 35,923 childhood cancer survivors diagnosed between 1970 and 1999. The CCSS cohort has been assembled through the efforts of 31 participating centers in the United States and Canada. CCSS is a resource in which to investigate current and future questions regarding consequences of therapy, genetic associations, disease processes and causation, interventions, and quality of life among childhood cancer survivors. This dataset outlines the demographic, primary cancer and treatment characteristics of the Overall CCSS Cohort (the Expansion Cohort as of January 2021 plus the Original Cohort).