Publicly available GWAS summary statistics, harmonized and imputed to GTEx v8' variant reference
<p># harmonized and imputed GWAS summary statistics</p> <p> </p> <p>* `harmonized_imputed_gwas.tar` contains 114 publicly available GWAS traits, harmonized and imputed to GTEx v8 reference</p> <p> </p> <p>* `gwas_metadata.txt` is a table with useful information about each trait, such as:</p> <p>- Tag: trait name (also in the file name)</p> <p>- PUBMED_Paper_Link: PUBMED or publication URL (if available)</p> <p>- Portal: URL to web portal from which data was downloaded</p> <p>- Consortium: GWAS Consortium authoring the data</p> <p>- Sample_Size: number of individuals covered in the study</p> <p>- Population: individuals'ancestry (EUR, EAS, etc)</p> <p>- abbreviation: short name used for figures</p> <p>- new_abbreviation: alternative name for additional figures</p> <p>- Deflation: whether imputed summary statistics exhibited deflation (i.e. association p-values are lower than expected by chance. The summary statistics imputation method is conservative, and in public GWAS with few observed variants (<2M), the distribution of p-values lags towards lower significance spectrums.</p> <p># Data usage policy</p> <p>When using this data, you must acknowledge the source by citing the publication "Widespread dose-dependent effects of RNA expression and splicing on complex diseases and traits" (https://doi.org/10.1101/814350).</p> <p># Disclaimer</p> <p>The data is provided "as is", and the authors assume no responsibility for errors or omissions. <br> The User assumes the entire risk associated with its use of these data. <br> The authors shall not be held liable for any use or misuse of the data described and/or contained herein. <br> The User bears all responsibility in determining whether these data are fit for the User's intended use. </p> <p>The information contained in these data is not better than the original sources from which they were derived,<br> and both scale and accuracy may vary across the data set. <br> These data may not have the accuracy, resolution, completeness, timeliness, or other characteristics<br> appropriate for applications that potential users of the data may contemplate. <br> <br> The user is responsible to comply with any data usage policy from the original GWAS studies;<br> refer to the list of traits described [here](https://www.biorxiv.org/content/10.1101/814350v1)<br> to identify their respective Consortia's requirements.</p> <p><br> THE DATA IS PROVIDED WITHOUT WARRANTY OF ANY KIND,<br> EXPRESS OR IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,<br> FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT.<br> IN NO EVENT SHALL THE AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER LIABILITY,<br> WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,<br> OUT OF OR IN CONNECTION WITH THE DATA OR THE USE OR OTHER DEALINGS IN THE DATA.</p>
ShareScore
28/100
Overall dataset sharing score
Score breakdown
These five areas show where the dataset supports — or may limit — practical reuse.
- Stewardship
- 8
- Harmonization
- 4
- Access
- 16
- Reuse readiness
- 0
- Engagement
- 0