The effects of intensive neurorehabilitation on sequence effect in Parkinson's disease patients with and without freezing of gait

<p><strong>This dataset includes </strong>raw data from the article &ldquo;The Effects of Intensive Neurorehabilitation on Sequence Effect in Parkinson&#39;s Disease Patients With and Without Freezing of Gait&rdquo;.</p> <p><strong>The aim of the study</strong> was to investigate the effects of a 4-week rehabilitation program on dSE in patients with PD with and without FOG.</p> <p><strong>The dataset show</strong> forty-three patients (30 males, 70.6 &plusmn; 7.5 years old) with idiopathic PD were enrolled. The subjects were divided into two groups: patients with (PD + FOG, n = 23) and without FOG (PD - FOG, n = 20). All patients underwent a standardized 4-week intensive rehabilitation in-hospital program. At hospital admission (T0) and discharge (T1), all subjects were evaluated with an inertial gait analysis for dSE recording</p> <p><strong>Results.&nbsp;</strong>At T0, the dSE was more negative in the PD + FOG group (&minus;0.80 &plusmn; 0.6) when compared to the PD &ndash; FOG group (&minus;0.39 &plusmn; 0.3) (p = 0.007), even when controlling for several clinical and demographic features. At T1, the dSE was reduced in the overall study population (p = 0.001), with a more pronounced improvement in the PD + FOG group (T0: &minus;0.80 &plusmn; 0.6; T1: &minus;0.23 &plusmn; 0.4) when compared to the PD &ndash; FOG group (T0: &minus;0.39 &plusmn; 0.3; T1: &minus;0.22 &plusmn; 0.5) (p = 0.012). At T1, we described in the overall study population an improvement in speed, cadence, stride duration, and stride length (p = 0.001 for all variables).</p>