Figure 2 in Leech anticoagulants are ancestral and likely to be multifunctional

Figure 2. Best-scoring maximum likelihood trees resulting from the analysis of destabilase (A; log likelihood [ln L] = −8230.744), manillase (B; ln L = −27279.363), saratin and leech antiplatelet protein (LAPP) (C; ln L = −4758.748) and cystatin (D; ln L = −2474.943) datasets. Branches drawn in black represent non-leech lineages; branches in red represent bloodfeeding leech lineages; branches in blue represent non-bloodfeeding leech lineages. Red boxes represent putative orthologues of archetypal leech anticoagulants. For the remaining gene trees, see the Supporting Information (Fig. S1).