Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells

<p>Novel Targets to Promote RGC Axon Regeneration (Park Lab)</p> <p>The aim of this project is to idenity genes and lipids that give subtypes of retinal ganglion cells a greate propensity to regenerate axons and form function synaptic connections. This work has been published in the following manuscripts:</p> <ul> <li><a href="https://pubmed.ncbi.nlm.nih.gov/31255486/">Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells</a>&nbsp;(2019-08-21)</li> <li><a href="https://pubmed.ncbi.nlm.nih.gov/31508459/">Lipid profiling dataset of the Wnt3a-induced optic nerve regeneration</a>&nbsp;(2019-05-24)</li> </ul> <p>Our results identify cell-type-specific induction of Thbs1 as a novel gene conferring high regenerative capacity.</p> <p>See the following visualizations to explore the findings:</p> <ul> <li><a href="https://viz.stjude.cloud/stjude/visualization/thrombospondin-1-mediates-axon-regeneration-in-retinal-ganglion-cells~55">Thrombospondin-1 Mediates Axon Regeneration in RGCs</a></li> </ul>