Fig. 4 in Natural biflavones are potent inhibitors against SARS-CoV-2 papain-like protease

Fig. 4. Possible interactions of biflavones 1, 7, and 6 with PLpro. (A–C) Binding interactions represented in the Corey-Pauling-Koltun (CPK) model. (D–F) Binding interactions represented in the ball-stick model. The interacting amino acid residues are labelled in black. The hydrogen bonds are indicated by yellow dashed lines with the distances given in Å. The P3 and P4 regions of the substrate binding pocket of PLpro are indicated by corresponding labels. (G–I) 2D diagram of the binding interactions. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)