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189
datasets available to search
ShareScore release 0.9.0
Dataset results
189 results for “nociception”
Designed NGF mimetics with reduced nociceptive signatures in neurons
GEO Series GSE292792. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Designed NGF mimetics with reduced nociceptive signatures in neurons
GEO Series GSE295544. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
The Nociceptive Activity of Peripheral Sensory Neurons is Modulated by the Neuronal Membrane Proteasome
GEO Series GSE261727. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
A population of Regulatory T cells controls nociception through enkephalins to restrain skin inflammation [plate scRNA-seq]
GEO Series GSE218063. Mus musculus. 384 samples. Type: Expression profiling by high throughput sequencing.
RNA-SEQ analysis of postnatal Ret-positive (EGFP-labeled) nociceptive (NaV1.8 population) dorsal root ganglia L345 or L6S1 neurons.
GEO Series GSE77893. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Nociception testing during fixed-wing ambulance flights.
<p>An interventional pilot study on the effects of flight-related environmental changes on the nociception of healthy volunteers.</p> <p><strong>Abstract</strong></p> <p><strong>Background:</strong> The effects of environmental changes during long-distance air ambulance flights on the somato-sensory system need further investigation. Changes in the nociceptive capacity are conceivable in lights of previous studies from related environmental settings. We investigated the feasibility of somato-sensory testing during air-ambulance flights and measured nociception in volunteers.</p> <p><strong>Methods:</strong> 25 healthy individuals were submitted to a test compilation analogous to the quantitative sensory testing battery - during actual air-ambulance flights. Measurements were paired around the major changes of external factors during take-off/climb and descent/landing. Bland-Altman-Plots were calculated to identify possible systemic effects.</p> <p><strong>Results:</strong> Bland-Altman-Analyses demonstrated that thresholds of stimulus detection and pain as well as above-threshold pain along critical waypoints of travel are not subject to systemic effects but only demonstrate random variations.</p> <p><strong>Conclusions:</strong> We provide a novel description of a real-life experimental set-up and demonstrate the general feasibility of somato-sensory testing during ambulance flights. Systematic effects on the nociception of healthy individuals are not apparent from our data. Our findings open up the possibility of future investigations into potential effects of ambulance flights on patients suffering from acute or chronic pain and in need of analgesia.</p>
A population of Regulatory T cells controls nociception through enkephalins to restrain skin inflammation.
GEO Series GSE301699. Mus musculus. 386 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of B16F10 tongue xenografts with or without inhibition of LN-innervating nociceptive nerves
GEO Series GSE218454. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Spinal nociceptive sensitization and plasma palmitoylethanolamide levels during experimentally induced migraine attacks
<p>This dataset comprises the evaluation of plasma anandamide (AEA) and palmitoylethanolamide (PEA) levels and spinal sensitization in a validated human model of migraine based on systemic nitroglycerin (NTG) administration.</p> <p>Twenty-four subjects with episodic migraine (MIG) and 19 healthycontrols (HC) underwent blood sampling and investigation of nociceptive withdrawal reflex thresholds (RTh: single-stimulusthreshold; TST: temporal summation threshold) before and 30 (T30), 60 (T60), and 120 (T120) minutes after sublingual NTGadministration (0.9 mg). At baseline, the MIG and HC groups were comparable for plasma AEA (P50.822) and PEA (P50.182)levels, and for RTh (P50.142) and TST values (P50.150). Anandamide levels increased after NTG administration (P50.022) inboth groups, without differences between them (P50.779). By contrast, after NTG administration, PEA levels increased in the MIGgroup at T120 (P50.004), while remaining stable in the HC group. Nitroglycerin administration induced central sensitization in theMIG group, which was recorded as reductions in RTh (P50.046) at T30 and T120, and in TST (P50.001) at all time points. In theHC group, we observed increases in RTh (P50.001) and TST (P50.008), which suggest the occurrence of habituation. We foundno significant correlations between the ES and neurophysiological parameters. Our findings suggest a role for PEA in the ictal phaseof episodic migraine. The ES does not seem to be directly involved in the modulation of NTG-induced central sensitization, which suggests that the observed PEA increase and spinal sensitization are parallel, probably unrelated, phenomena.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.