Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
711
datasets available to search
ShareScore release 0.9.0
Dataset results
711 results for “respiratory infection”
TREATment of Lower Respiratory Tract Infection in Selected Hospitals in Southern Sri Lanka (TREAT-SL): a Stepped-Wedge Cluster Randomized Trial
ClinicalTrials.gov study NCT06331364. IPD Sharing: NO. Countries: 0. Publications: 0.
Safety and Efficacy Study of GS-5806 in Healthy Volunteers Infected With Respiratory Syncytial Virus (RSV)
ClinicalTrials.gov study NCT01756482. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Study of Vitamin D for the Prevention of Acute Respiratory Infections in Children
ClinicalTrials.gov study NCT02046577. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Retrospective Evaluation of Clinical, Virological and Serological Data in Patients With Mild Acute Upper Respiratory Tract Infections
ClinicalTrials.gov study NCT05134766. IPD Sharing: NO. Countries: 1. Publications: 8.
Myocardial Involvement of Severe Acute Respiratory Syndrome-Cov-2 (Covid19) Infected Patients
ClinicalTrials.gov study NCT04358952. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Efficacy and Safety of L. Plantarum and P. Acidilactici in Children With Upper Respiratory Tract Infections
ClinicalTrials.gov study NCT05279534. IPD Sharing: Not stated. Countries: 1. Publications: 4.
A Study to Investigate the Effect of Probiotics (L. Reuteri ATCC PTA 5289 and L. Reuteri DSM 17938) on Symptoms of Viral Upper Respiratory Tract Infections in Children
ClinicalTrials.gov study NCT06205966. IPD Sharing: NO. Countries: 1. Publications: 1.
Comparison of Supportive Therapies for Symptom Relief From Pediatric Upper Respiratory Infections (URIs)
ClinicalTrials.gov study NCT01814293. IPD Sharing: Not stated. Countries: 1. Publications: 13.
Procalcitonin Guided Antibiotic Use in Acute Respiratory Tract Infections (PARTI)-Study
ClinicalTrials.gov study NCT00099840. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Vitamin D Supplementation and Upper Respiratory Tract Infections in Adolescent Swimmers
ClinicalTrials.gov study NCT01215682. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Stenotrophomonas isolates from patients with cystic fibrosis and other chronic respiratory infections
Open the record for dataset details and reuse information.
Data from: Does hugging provide stress-buffering social support? A study of susceptibility to upper respiratory infection and illness
Open the record for dataset details and reuse information.
Data from: Nasopharyngeal microbiome profiles in rural Venezuelan children are associated with respiratory and gastrointestinal infections
Open the record for dataset details and reuse information.
Co-infection best predicts respiratory viral infection in a wild host
Open the record for dataset details and reuse information.
Data from: Type 2 porcine reproductive and respiratory syndrome virus infection increases apoptosis at the maternal-fetal interface in late gestation pregnant gilts
The pathogenesis of fetal death associated with porcine reproductive and respiratory syndrome (PRRS) is hypothesized to be a consequence of PRRS virus-induced apoptosis at the maternal-fetal interface (MFI). The objectives of this study were to evaluate distribution and degree of apoptosis in the uterine and fetal placental tissues during the experimental type 2 PRRS virus (PRRSV) infection and determine associations between apoptosis at the MFI, PRRSV RNA concentration and antigen staining intensity, PRRSV-induced microscopic lesions, and fetal preservation status. A total of 114 naïve, high-health pregnant gilts were inoculated with type 2 PRRSV on gestation day 85±1 with euthanasia 21 days later; 19 sham-inoculated gilts served as controls. Two hundred and fifty samples of uterine tissue with fetal placenta were selected based on negative, low PRRSV RNA, and high PRRSV RNA concentration (0, < or > 2.7 log10 copies/mg, respectively). TUNEL assay was used to detect apoptosis in the endometrium and at the MFI. PRRSV RNA concentration and numbers of PRRSV immunopositive cells in uterine and placental tissue were positively associated with the severity of apoptosis in the endometrium and the MFI (P<0.001, P<0.05 and P<0.001, respectively). The number of TUNEL positive cells at the MFI was also positively associated with the severity (P<0.001) of vasculitis, but not total numbers of inflammatory cells in the endometrium. Increased numbers of TUNEL positive cells at the MFI were associated with PRRSV load in the fetal thymus, and greater odds of meconium staining of the fetus at 21 days post infection (P<0.001 for both). These findings suggest an important role of apoptosis in the pathogenesis of uterine epithelial and trophoblastic cell death at the MFI. Moreover, apoptosis at the MFI is significantly associated with fetal demise during in utero type 2 PRRSV infection.
PREVALENCE ANALYSIS INCIDENCE OF UPPER RESPIRATORY COVID-19 - INFECTED PATIENTS
Open the record for dataset details and reuse information.
raw data - Pharmacokinetic/ pharmacodynamic analysis based on the data from a randomized phase I study justifies the optimal dosing regimens of the 10:1 formulation of amoxicillin/clavulanic acid for treatment of respiratory and urinary tract infections
Open the record for dataset details and reuse information.
Data from: Tuberculosis-like respiratory infection in 245-million-year-old marine reptile suggested by bone pathologies
An absence of archaeological and palaeontological evidence of pneumonia in the remote past contrasts with its recognition in the more recent archaeologic record. We document an apparent infection-mediated periosteal reaction affecting the dorsal ribs in a Middle Triassic eosauropterygian historically referred to as 'Proneusticosaurus' silesiacus. High-resolution X-ray microtomography (XMT) and histological studies of the pathologically-altered ribs revealed the presence of a continuous solid periosteal reaction with multiple superficial blebs (protrusions) on the visceral surfaces of several ribs. Increased vascularization and elevated lines of arrested growth document that the pathology was the result of a multi-seasonal disease. While visceral surface localization of this periosteal reaction represents the earliest identified evidence for pneumonia, the blebs may have an additional implication: they have only been previously recognized in humans with tuberculosis. Parsimonious with this diagnosis is the presence of focal vertebral erosions, another manifestation of tuberculosis in humans.
Data from: Respiratory virus infection up-regulates TRPV1, TRPA1 and ASICS3 receptors on airway cells
Receptors implicated in cough hypersensitivity are transient receptor potential vanilloid 1 (TRPV1), transient receptor potential cation channel, Subfamily A, Member 1 (TRPA1) and acid sensing ion channel receptor 3 (ASIC3). Respiratory viruses, such as respiratory syncytial virus (RSV) and measles virus (MV) may interact directly and/or indirectly with these receptors on sensory nerves and epithelial cells in the airways. We used in vitro models of sensory neurones (SHSY5Y or differentiated IMR-32 cells) and human bronchial epithelium (BEAS-2B cells) as well as primary human bronchial epithelial cells (PBEC) to study the effect of MV and RSV infection on receptor expression. Receptor mRNA and protein levels were examined by qPCR and flow cytometry, respectively, following infection or treatment with UV inactivated virus, virus-induced soluble factors or pelleted virus. Concentrations of a range of cytokines in resultant BEAS-2B and PBEC supernatants were determined by ELISA. Up-regulation of TRPV1, TRPA1 and ASICS3 expression occurred by 12 hours post-infection in each cell type. This was independent of replicating virus, within the same cell, as virus-induced soluble factors alone were sufficient to increase channel expression. IL-8 and IL-6 increased in infected cell supernatants. Antibodies against these factors inhibited TRP receptor up-regulation. Capsazepine treatment inhibited virus induced up-regulation of TRPV1 indicating that these receptors are targets for treating virus-induced cough.
Contribution of genetic variants to the susceptibility of infection by Severe Acute Respiratory Syndrome to CoV-2 in a population of individuals residing in Ecuador
<p>The file presents, in the table, the genotype and alleles obtained from each subject participating in the laboratory phase that are discriminated by groups (control and case groups).<br> The allelic frequencies calculated in the Microsoft Excel program are also presented.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.