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2,143 results for “All Spinal Cord”
Circular RNAs expression profiles and potential key molecules incompletely transected spinal cord injury.
GEO Series GSE156999. Rattus norvegicus. 6 samples. Type: Expression profiling by high throughput sequencing.
Spinal Cord Injury Murine Model
GEO Series GSE5296. Mus musculus. 96 samples. Type: Expression profiling by array.
Dataset related to article "Intramedullary spinal cord tumors: the value of intraoperative neurophysiological monitoring in a series of 57 cases from two Italian centres."
<p>BACKGROUND:</p> <p>Intramedullary spinal cord tumors are rare lesions of the central nervous system. Anatomical, molecular and radiological features are well defined, but correct management is still matter of debate. Pertinent literature has reported conflicting opinions regarding the use of intraoperative electrophysiological monitoring (IONM) in the surgical treatment of this kind of lesions, recently. We report a retrospective study from two Italian centres, in order to highlight the usefulness of IONM in the management of intramedullary lesions.</p> <p>METHODS:</p> <p>We performed a retrospective review of patients with intramedullary spinal tumor who underwent surgical resection from February 2011 to February 2018 in two different institutions. Clinical and radiological data, lesion features, timing of symptom onset and IONM findings were record ed . The IONM includ ed somatosensory-evoked potentials(SSEP), motor-evoked potentials(MEP) and D-Wave whenever possible. We evaluated the outcome according to the Modified McCormick scale. We also evaluated the accuracy and relevance of surgical outcomes for each evoked potential(SSEP, MEP, D-Wave).</p> <p>RESULTS:</p> <p>A total of 57 patients were included. A gross total removal was achieved in 46 cases. Neurological follow-up was assessment at 3 days, and 3 and 6 months after surgery. Comparing the preoperative status and 6 months follow-up: the M-McCormick scale showed a neurological stability for 30 patients (52.63%), a worsening of neurological status for 7 patients (12.28%) and an improvement for 20 patients (35.08%). IONM presented high accuracy (sensibility of 100% and specificity of 95.65%) and significantly pred icted postoperative permanent motor d eficits(P<0.0001; AUC=0.978). D-Wave appeared to have significant greater predictive value than MEP and especially SSEP alone(0.967 vs 0.722 vs 0.542; P = 0.044 and P<0.001 respectively).</p> <p>CONCLUSIONS:</p> <p>The gold standard in the intramedullary lesion treatment is maximal safe resection with good neurological outcome, as shown in our patients. The use of IONM is helpful in intramedullary tumors resection in order to minimize postoperative neurological deficits and our analysis suggests that the use of D-Wave presents a statistically significant higher accuracy for predicting postoperative deficits than SSEP and MEP alone.</p>
Decomposing the complexity of heart-rate variability by the multifractal–multiscale approach to detrended fluctuation analysis: an application to low-level spinal cord injury
<p>Raw data for reproducing (figure 2) and the main results of the paper: doi: 10.1088/1361-6579/ab2b4a</p>
Semaphorin3C identified as mediator of neuroinflammation and microglia polarization after spinal cord injury
Open the record for dataset details and reuse information.
Code for scRNA-seq analysis of electrically treated spinal cord
Open the record for dataset details and reuse information.
3,4-Dimethoxychalcone, a caloric restriction mimetic, enhances the TFEB-mediated autophagy and alleviates pyroptosis and necroptosis after spinal cord injury
GEO Series GSE210033. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Exon Expression Changes in the Spinal Cords of Lewis Rats with Myelin Basic Protein-Induced Experimental Autoimmune Encephalomyelitis (EAE)
GEO Series GSE39120. Rattus norvegicus. 8 samples. Type: Expression profiling by array.
Transcriptional changes after spinal cord injury: recruitment of afferents distal to the site of injury
GEO Series GSE132552. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
The gene expression of the brain and spinal cord
GEO Series GSE252641. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Mechanism of TIA1 in spinal cord injury mice
GEO Series GSE268047. Mus musculus. 8 samples. Type: Expression profiling by high throughput sequencing.
Expression data of miRNAs and lncRNAs from the lumbosacral spinal cord of fetal rats with anorectal malformations in embryonic days 17 and 19
GEO Series GSE190333. Rattus norvegicus. 24 samples. Type: Non-coding RNA profiling by high throughput sequencing.
Expression data from ICR mouse spinal cords - normal or injured spinal cord
GEO Series GSE67515. Mus musculus. 10 samples. Type: Expression profiling by array; Non-coding RNA profiling by array.
Expression data from embryonic mouse cervical spinal cords
GEO Series GSE47953. Mus musculus. 6 samples. Type: Expression profiling by array.
Identification of genes expressed by spinal cord neurons after axotomy and during axon regeneration
GEO Series GSE2925. Rattus norvegicus. 17 samples. Type: Expression profiling by array.
ECM enriched in developing human spinal cord
GEO Series GSE131979. Homo sapiens. 2 samples. Type: Expression profiling by array.
Spinal Cord Trauma Supraspinal Tracts
GEO Series GSE2270. Rattus norvegicus. 244 samples. Type: Expression profiling by array.
Identification of axonal regeneration-associated genes after spinal cord injury in adult zebrafish
GEO Series GSE56842. Danio rerio. 9 samples. Type: Expression profiling by array.
Murine Spastic Spinal Cord
GEO Series GSE1800. Mus musculus. 16 samples. Type: Expression profiling by array.
Administration of tamoxifen regulates changes in gene expression during the acute phase of traumatic spinal cord injury
GEO Series GSE229618. Rattus norvegicus. 22 samples. Type: Expression profiling by array.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.