Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
6,512
datasets available to search
ShareScore release 0.7.1
Dataset results
6,512 results for “clinical trial”
Figure 1 from: Abu-Samak MS, Hasoun LZ, Barham A, Mohammad BA, Mosleh I, Aljaberi A, Awwad SH (2021) The supplementary effects of omega-3 fatty acid alone and in a combination with vitamin D3 on serum leptin levels: A randomized clinical trial on men and women with vitamin D deficiency. Pharmacia 68(3): 517-525. https://doi.org/10.3897/pharmacia.68.e64422
Figure 1 CONSORT flow diagram for the study, indicating the number of subjects screened, recruited, and randomly assigned to the different intervention groups.
Representation of women in stroke clinical trials: a review of 281 trials involving over 500,000 participants
<p>Objective:<b> </b>Women have been under-represented in clinical trials areas of cardiovascular disease but there is less certainty over the level of disparity specifically in stroke. We examined the participation of women in trials according to stroke prevalence in the population.</p> <p>Methods: Published randomized controlled trials with ≥100 participants enrolled between 1990 and 2020 were identified from ClinicalTrials.gov. To quantify sex disparites in enrolment we calculated the participation to prevalence ratio (PPR), defined as the percentage of women participating in a trial against the prevalence of women in the disease population.</p> <p>Results:<b> </b>There were 281 stroke trials<b> </b>eligible for analyses with a total of 588,887 participants, of whom 37.4 % were women. Overall, women were represented at a lower proportion relative to their prevalence in the underlying population (mean PPR 0.84; 95% confidence interval [CI] (0.81 to 0.87)). The greatest differences were observed in trials of intracerebral hemorrhage (PPR 0.73; 95% CI 0.71 to 0.74), trials with a mean age of participants <70 years (PPR 0.81; 95% CI (0.78 to 0.84)), non-acute interventions (PPR 0.80; 95% CI (0.76 to 0.84)) and rehabilitation trials (PPR 0.77; 95% CI 0.71 to 0.83)). These findings did not significantly change over the period from 1990 to 2020 (p for trend = 0.201).</p> <p>Conclusion: Women are disproportionately represented in stroke trials relative to the burden of disease in the population. Clear guidance and effective implementation strategies are required to improve the inclusion of women and thus broader knowledge of the impact of interventions in clinical trials.</p>
Opinion of ethics committee representatives on the use of social networks and new technologies in clinical trials. Nominal group
<p>Nominal group database to find out the opinion of ethics committee representatives on the use of social networks and new technologies in clinical trials.</p>
Raw Data for the article: Donor Simvastatin Treatment Is Safe and Might Improve Outcomes After Liver Transplantation: A Randomized Clinical Trial
<p><strong>Background: </strong>The current curative approaches for ischemia/reperfusion injury on liver transplantation are still under debate for their safety and efficacy in patients with end-stage liver disease. We present the SIMVA statin donor treatment before Liver Transplants study.</p> <p><strong>Methods: </strong>SIMVA statin donor treatment before Liver Transplants is a monocentric, double-blind, randomized, prospective tial aiming to compare the safety and efficacy of preoperative brain-dead donors' treatment with the intragastric administration of 80 mg of simvastatin on liver transplant recipient outcomes in a real-life setting. Primary aim was incidence of patient and graft survival at 90 and 180 d posttransplant; secondary end-points were severe complications.</p> <p><strong>Results: </strong>The trial enrolled 58 adult patients (18-65 y old). The minimum follow-up was 6 mo. No patient or graft was lost at 90 or 180 d in the experimental group (n = 28), whereas patient/graft survival were 93.1% ( P = 0.016) and 89.66% ( P = 0.080) at 90 d and 86.21% ( P = 0.041) and 86.2% ( P = 0.041) at 180 d in the control group (n = 29). The percentage of patients with severe complications (Clavien-Dindo ≥IIIb) was higher in the control group, 55.2% versus 25.0% in the experimental group ( P = 0.0307). The only significant difference in liver tests was a significantly higher gamma-glutamyl transferase and alkaline phosphatase at 15 d ( P = 0.017), ( P = 0.015) in the simvastatin group.</p> <p><strong>Conclusions: </strong>Donor simvastatin treatment is safe, and may significantly improve early graft and patient survival after liver transplantation, although further research is mandatory.</p>
Dataset of Clinical Trial Protocols for Intervertebral Disc Degeneration Management (2013-2024)
<div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <div> <p>This dataset encompasses a detailed collection of clinical trial protocols focused on the management of Intervertebral Disc Degeneration (IVD) from January 2013 to September 2024. It includes a diverse range of interventions, highlighting device, drug, and biological treatments, and documents the evolving strategies in response to the shifting landscape of pain management, particularly in the post-opioid epidemic era. The protocols have been rigorously compiled to identify trends, assess the effectiveness of various treatment modalities, and pinpoint knowledge gaps in the current research. By providing standardized data, this dataset serves as a valuable resource for researchers and clinicians aiming to enhance therapeutic approaches and outcomes for IVD patients worldwide. The inclusion of multiple intervention types and the comprehensive nature of the data make this collection a pivotal tool for advancing research and improving patient care in the field of spinal health.</p> </div> </div> </div> </div> </div> <div> <div> </div> </div> </div> </div> </div> </div> </div> </div> </div> </div> <div> <div> <div> <div> <div> <div> </div> <div> <div> <div> <div> <div> <div> </div> </div> </div> <div> </div> </div> </div> </div> </div> </div> </div> </div> </div>
Clinical Trial to Evaluate the Efficacy, Pharmacokinetics (PK) Interactions and Safety of Dolutegravir Plus 2 Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV-1-Infected Solid Organ Transpla
ClinicalTrials.gov study NCT03360682. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Trial Assessing 5-HT3 Receptor Antagonist (Ramosetron) for the Treatment of Anterior Resection Syndrome
ClinicalTrials.gov study NCT02869984. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Identifying Risk Factors for Bone Tissue Death in Young Patients With Acute Lymphoblastic Leukemia Treated on Clinical Trial CCG-1882
ClinicalTrials.gov study NCT00898469. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Assessing Clinical Trial Experiences of Patients With Osteosarcoma
ClinicalTrials.gov study NCT05535283. IPD Sharing: UNDECIDED. Countries: 0. Publications: 3.
Clinical Trial on Ladarixin Adjunctive Therapy to Improve Glycemic Control in Type 1 Diabetes.
ClinicalTrials.gov study NCT05368402. IPD Sharing: NO. Countries: 1. Publications: 0.
Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor
ClinicalTrials.gov study NCT07078357. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Clinical Trial of Sound-Based Versus Behavioral Therapy for Tinnitus
ClinicalTrials.gov study NCT03022084. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Clinical Trial Evaluating Rituximab in Ocular Cicatricial Pemphigoid
ClinicalTrials.gov study NCT00584935. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Randomized Contralateral Clinical Trial With Single-piece (SN60WF) vs. Three Piece (MA60AC) AcrySof Intraocular Lenses (IOLs) on Development of Posterior Chamber Opacification (PCO).
ClinicalTrials.gov study NCT00758745. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Turmeric Based Therapy in the Treatment of Psoriasis: A Clinical Trial
ClinicalTrials.gov study NCT04071106. IPD Sharing: YES. Countries: 0. Publications: 5.
Stimulating Neural Activity to Improve Blood Flow and Reduce Amyloid: Path to Clinical Trials
ClinicalTrials.gov study NCT03543878. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Pilot Phase III Clinical Trial of JDP-205 IV Injection for Treatment of Acute Urticaria
ClinicalTrials.gov study NCT02023164. IPD Sharing: NO. Countries: 2. Publications: 0.
A Clinical Trial of Locally Made Titanium Miniplate and Screw in Maxillofacial Fractures Management
ClinicalTrials.gov study NCT04279925. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Clinical Investigation to Evaluate the Hemanext® Oxygen Reduction System - Pivotal Trial
ClinicalTrials.gov study NCT03301779. IPD Sharing: NO. Countries: 1. Publications: 0.
Effectiveness of rTMS on Pain and Quality of Life in Patients With Cancer Neuropathic Pain. Clinical Trial.
ClinicalTrials.gov study NCT05480410. IPD Sharing: YES. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.