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1,274 results for “Disease Model”
Dataset related to article "SUNITINIB-MEDIATED INHIBITION OF STAT3 IN SKELETAL MUSCLE AND SPINAL CORD DOES NOT AFFECT THE DISEASE IN A MOUSE MODEL OF ALS"
<p>Dataset related to the article</p>
Predicting gut microbial behavior in human diseases via community metabolic modeling and machine learning
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A novel and accurate full-length HTT mouse model for Huntington's disease
<p>Here we report the generation and characterization of a novel Huntington's disease (HD) mouse model BAC226Q by using a bacterial artificial chromosome (BAC) system, expressing full-length human HTT with ~226 CAG-CAA repeats and containing endogenous human HTT promoter and regulatory elements. BAC226Q recapitulated a full-spectrum of age-dependent and progressive HD-like phenotypes without unwanted and erroneous phenotypes. BAC226Q mice developed normally, and gradually exhibited HD-like mood and cognitive phenotypes at 2 months. From 3-4 months, BAC226Q mice showed robust progressive motor deficits. At 11 months, BAC226Q mice showed significant reduced life span, gradual weight loss and exhibit neuropathology including significant brain atrophy specific to striatum and cortex, striatal neuronal death, widespread huntingtin inclusions and reactive pathology. Therefore, the novel BAC226Q mouse accurately recapitulating robust, age-dependent, progressive HD-like phenotypes will be a valuable tool for studying disease mechanisms, identifying biomarkers and testing gene-targeting therapeutic approaches for HD.</p>
Temperature-based phenology model of African citrus triozid (Trioza erytreae Del Guercio): Vector of citrus greening disease.
<p>The data in this dataset show the developmental stages of the African citrus psyllid, vector of citrus greening disease. The data consist of egg development time and survival and, development time and survival of the 1st 2nd, 3rd, 4th and 5th nymphal instar stages of the African citrus triozid. </p>
Real-time detection and grading of degenerative disc disease using YO-LO-v5 model
<p>Video 1: Real-time detection and grading of degenerative disc disease using YOLO-v5 model</p>
Ocular graft vs host disease mouse model
<p>Ocular graft versus host disease (OGvHD) develops in nearly 50% of patients after allogeneic hematopoietic stem cell transplantation (HSCT) and frequently manifests as dry eye disease (DED). The aim of this study was to evaluate the efficacy of a single subconjunctival (SCJ) dose of adeno-associated virus (AAV) gene therapy encoding human leukocyte antigen G (HLA-G) isoforms 1 and 5 to induce ocular immune tolerance and inhibit development of clinical signs of OGvHD.</p>
Diseases (Black Rot and Powdery Mildew) model results for cultivation period of 2021 (Spain and Greece) [Dataset]
<p>This dataset (csv files) contains the results of the models for two diseases (Black Rot and Powdery Mildew) during the cultivation period of 2021 for all the pilot areas of Grapevine project. The pilot areas are the region of Aragon (Spain) in Calatayud, Campo de Borja, Cariñena and Somontano and Chatzivaritis estate (Greece). In order to avoid zero tables (as in the most of the period there are no risks for diseases) in the csv files are only presented the moments in hourly basis that risk diseases are computed.</p> <p>A detailed description of the models is found in deliverable D3.2 GRAPEVINE Plagues and Diseases Models v2 https://zenodo.org/record/7575773</p>
"SIMULATION MODELING OF CORONARY ARTERY DISEASE: A TOOL FOR CLINICAL DECISION SUPPORT"
ClinicalTrials.gov study NCT04448691. IPD Sharing: NO. Countries: 0. Publications: 3.
Towards Telemonitoring in Immune-Mediated Inflammatory Diseases: Implementation of a Mixed Attention Model (IMIDOC)
ClinicalTrials.gov study NCT06273306. IPD Sharing: NO. Countries: 0. Publications: 1.
The Benchmark Clinic: An Interdisciplinary Comprehensive Care Model for People With Parkinson Disease
ClinicalTrials.gov study NCT04555720. IPD Sharing: NO. Countries: 1. Publications: 0.
Health Management Model Construction and Effect Evaluation of Hypertension Patients Based on Disease-related Health Literacy
ClinicalTrials.gov study NCT04327102. IPD Sharing: UNDECIDED. Countries: 0. Publications: 12.
Model for the Integral Assessment of Chronic Disease Management Supported in Information Technology and Communication.
ClinicalTrials.gov study NCT02447562. IPD Sharing: Not stated. Countries: 0. Publications: 3.
Randomized Controlled Trial of the Smart O2O Model Development for Chronic Diseases Management Through Digital Health
ClinicalTrials.gov study NCT06150508. IPD Sharing: NO. Countries: 0. Publications: 1.
Computational Modeling of 60 Hz Subthalamic Nucleus Deep Brain Stimulation for Gait Disorder in Parkinson's Disease
ClinicalTrials.gov study NCT04184791. IPD Sharing: NO. Countries: 1. Publications: 0.
Home-based Conservative Care Model for Advanced Kidney Disease
ClinicalTrials.gov study NCT06411613. IPD Sharing: YES. Countries: 1. Publications: 0.
Personalized Infliximab Induction Strategy With Model-informed Dosing in Patients With Crohn's Disease
ClinicalTrials.gov study NCT04974099. IPD Sharing: NO. Countries: 1. Publications: 0.
Data from: Low-dose proton radiation effects in a transgenic mouse model of Alzheimer's Disease - implications for space travel
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Data from: Using multi-response models to investigate pathogen coinfections across scales: insights from emerging diseases of amphibians
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Data from: Bayesian vector transmission model detects conflicting interactions from transgenic disease‐resistant grapevines
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Data from: Correlations of behavioral deficits with brain pathology assessed through longitudinal MRI and histopathology in the HDHQ150/Q150 mouse model of Huntington's disease
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ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.