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TABLE 3 in Finite element analysis of the proximal phalanx of the thumb in Hominoidea during simulated stone tool use
<p>TABLE 3. — Mesh characteristics for each one of the specimens.Abbreviations: <b>a</b>, volume of the cortical bone; <b>b</b>, volume of trabecular bone; <b>c</b>, number of elements used to create the mesh for each FE model.</p><table><tbody><tr><th><b>Specimen</b></th><th><b>Volume CB (mm</b> <b>3</b><b>)</b> <b>a</b></th><th><b>Volume TB (mm</b> <b>3</b><b>)</b> <b>b</b></th><th><b>N <b>elementsc</b></b></th></tr></tbody><tbody><tr><th>Modern human</th><td>1012.8</td><td>651.1</td><td>225729</td></tr><tr><th>Neanderthal</th><td>733.3</td><td>662.6</td><td>240469</td></tr><tr><th>Chimpanzee</th><td>1046.1</td><td>178.6</td><td>160103</td></tr><tr><th>Gorilla</th><td>1642.9</td><td>577.9</td><td>225710</td></tr><tr><th>Orangutan</th><td>610.1</td><td>542.8</td><td>199857</td></tr><tr><th>Gibbon</th><td>250.7</td><td>65.9</td><td>311431</td></tr></tbody></table>
APPENDIX 1 in Finite element analysis of the proximal phalanx of the thumb in Hominoidea during simulated stone tool use
<p>APPENDIX 1. — Loads applied to the models for each one of the species under analysis and simulated loading scenarios. Abbreviations: <b>a</b>, forces (<b>N</b>) and angles (Ɵ) relative to the longitudinal axes of the bone; <b>b</b>, muscle forces for the human and chimpanzee reference models, respectively, are separate by a slash; <b>c</b>, force reactions in the proximal and distal joints were scaled to remove size effects when computing stress distributions.</p><table><tbody><tr><th>Specimen</th><th>SC</th><th>HRFa</th><th>FPB HS /FPB PTb</th><th>AP HS /AP PTb</th><th>EPB HS /EPB PTb</th><th>ABP HS /ABP PTb</th><th>JRFc d</th><th></th><th><b><b>JRFc</b> mc</b></th><th></th></tr></tbody><tbody><tr><th></th><td></td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td><td><b>N</b></td><td>Ɵ</td></tr><tr><th>Modern Human</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>17.95/37.20 13.49/27.95 17.95/37.20 13.49/27.95</td><td>45 45 45 45</td><td>38.79/66.43 29.15/49.91 38.79/66.43 29.15/49.91</td><td>61.2 61.2 61.2 61.2</td><td>4.33/28.75 2.74/18.18 4.33/28.75 2.74/18.18</td><td>16.7 16.7 16.7 16.7</td><td>5.28/35.94 3.34/22.72 5.28/35.94 3.34/22.72</td><td>180 180 180 180</td><td>44.06/89.27 28.26/61.46 45.21/90.33 30.70/63.62</td><td>180 180 180 180</td><td>38.81/114.1 28.02/78.76 37.96/113.3 26.36/77.14</td><td>180 180 180 180</td></tr><tr><th>Neanderthal</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>14.47/29.99 10.87/22.54 14.47/29.99 10.87/22.54</td><td>45 45 45 45</td><td>31.28/53.56 23.50/40.24 31.28/53.56 23.50/40.24</td><td>61.2 61.2 61.2 61.2</td><td>3.49/23.18 2.21/14.66 3.49/23.18 2.21/14.66</td><td>16.7 16.7 16.7 16.7</td><td>4.26/28.98 2.69/18.32 4.26/28.98 2.69/22.72</td><td>180 180 180 180</td><td>35.55/72.02 22.79/49.58 36.46/72.85 24.75/51.29</td><td>180 180 180 180</td><td>30.75/91.35 22.36/63.11 30.27/90.88 21.41/62.18</td><td>180 180 180 180</td></tr><tr><th>Chimpanzee</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>18.34/38.01 13.78/28.56 18.34/38.01 13.78/28.56</td><td>45 45 45 45</td><td>39.64/67.88 29.78/51.00 39.64/67.88 29.78/51.00</td><td>61.2 61.2 61.2 61.2</td><td>– – – –</td><td>– – – –</td><td>5.39/36.72 3.41/23.22 5.39/36.76 3.41/23.22</td><td>180 180 180 180</td><td>43.78/82.63 28.05/57.36 45.11/83.92 30.92/60.02</td><td>180 180 180 180</td><td>35.51/90.61 26.15/64.17 35.78/90.89 26.7/64.7</td><td>180 180 180 180</td></tr><tr><th>Gorilla</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>24.78/51.36 18.62/38.59 24.78/51.36 18.62/38.36</td><td>45 45 45 45</td><td>53.55/91.71 40.24/68.91 53.55/91.71 40.24/68.91</td><td>61.2 61.2 61.2 61.2</td><td>5.97/39.69 3.78/25.10 5.97/39.69 3.78/25.10</td><td>16.7 16.7 16.7 16.7</td><td>7.29/49.61 4.61/31.37 7.29/49.61 4.61/31.37</td><td>180 180 180 180</td><td>61.17/125.1 39.33/86.13 64.27/128.2 45.94/92.39</td><td>180 180 180 180</td><td>49.14/144.11 35.31/99.38 49.57/144.53 36.15/100.2</td><td>180 180 180 180</td></tr><tr><th>Orangutan</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>19.74/40.91 14.83/30.74 19.74/40.91 14.83/30.74</td><td>45 45 45 45</td><td>42.66/73.06 32.06/54.90 42.66/73.06 32.06/54.90</td><td>61.2 61.2 61.2 61.2</td><td>– – – –</td><td>– – – –</td><td>5.80/39.52 3.67/24.99 5.80/39.52 3.67/24.99</td><td>180 180 180 180</td><td>47.62/89.76 30.56/62.34 49.01/91.09 33.44/65.02</td><td>180 180 180 180</td><td>47.85/117.2 34.51/82.77 50.55/119.84 39.78/87.92</td><td>180 180 180 180</td></tr><tr><th>Gibbon</th><td>1 2 3 4</td><td>3.92 7.65 3.92 7.65</td><td>90 90 45 45</td><td>7.08/14.66 5.32/11.02 7.08/14.66 5.32/11.02</td><td>45 45 45 45</td><td>15.29/26.1 11.49/19.68 15.29/26.19 11.49/19.68</td><td>61.2 61.2 61.2 61.2</td><td>– – – –</td><td>– – – –</td><td>2.08/14.17 1.32/8.96 2.08/14.17 1.32/8.96</td><td>180 180 180 180</td><td>17.75/32.87 11.25/22.87 17.88/33.25 12.1/23.65</td><td>180 180 180 180</td><td>19.08/45.46 13.75/32.18 19.64/46.00 14.84/33.24</td><td>180 180 180 180</td></tr></tbody></table>
TABLE 1 in Finite element analysis of the proximal phalanx of the thumb in Hominoidea during simulated stone tool use
<p>TABLE 1. — Sample. Abbreviations: <b>a</b>, age of individuals, if known; unk: unknown. <b>b</b>, M: male; F: female. <b>c</b>, R: right; L: left.</p><table><tbody><tr><th><b>Species</b></th><th><b>Common name</b></th><th><b>Age a</b></th><th><b>Sex b</b></th><th><b>Side</b></th><th><b>Digital database/ <b>no</b></b></th><th><b>CT/microCT resolution (mm)</b></th></tr></tbody><tbody><tr><th><i>Homo sapiens</i></th><td>Modern human</td><td>59</td><td>M</td><td>R</td><td>None</td><td>0.08</td></tr><tr><th><i>Homo neanderthalensis</i></th><td>Neanderthal</td><td>unk</td><td>unk</td><td>R</td><td>NESPOS/ Krapina 202</td><td>0.03</td></tr><tr><th><i>Pan troglodytes</i></th><td>Chimpanzee</td><td>29</td><td>M</td><td>L</td><td>KURPI/345</td><td>0.219</td></tr><tr><th><i>Gorilla gorilla</i></th><td>Gorilla</td><td>38</td><td>M</td><td>R</td><td>KUPRI/1353</td><td>0.500</td></tr><tr><th><i>Pongo pygmaeus</i></th><td>Orangutan</td><td>32</td><td>F</td><td>R</td><td>None</td><td>0.03</td></tr><tr><th><i>Hylobates lar</i></th><td>Gibbon</td><td>33</td><td>M</td><td>R</td><td>KUPRI/465</td><td>0.250</td></tr></tbody></table>
Development of an FKBP12-recruiting Chemical-Induced Proximity DNA-Encoded Library and its application in the discovery of an autophagy potentiator
<p><strong>Chemical inducers of proximity (CIPs) are molecules that recruit one protein to another and introduce new functionalities toward modulating protein states and activities. While CIP-mediated recruitment of E3 ligases is widely exploited for the development of degraders, other therapeutic modalities remain underexplored. We describe the first non-degrader CIP-DNA-Encoded Library (CIP-DEL) that recruits FKBP12 to target proteins using non-traditional acyclic structures, with an emphasis on introducing stereochemically-diverse and rigid connectors to attach the combinatorial library. We deployed this strategy to modulate ATG16L1 T300A, which confers genetic susceptibility to Crohn’s disease, and identified a compound that stabilizes the variant protein against Caspase-3 cleavage in a FKBP12-independent manner. We demonstrate in cellular models that this compound potentiates autophagy, reverses the xenophagy defects, and increases cytokine secretion characteristic of ATG16L1 T300A. This study provides a platform to access new chemical space for CIP design to achieve novel therapeutic modalities guided by human genetics.</strong></p>
Proximate analysis parameters for residual biomass samples from Southeast USA.
<p>Proximate analysis parameters for residual biomass samples for 142 samples collected from different logging mills in the Southeast USA for a USDA-AFRI research study (Grant.gov grant#: 12688125).</p>
Data set of "Effect of Proximity, Burden, and Position on the Power Quality Accuracy Performance of Rogowski Coils"
<p>The uploaded data set contains all the measurements collected during the research that led to the publication of " "Effect of Proximity, Burden, and Position on the Power Quality Accuracy Performance of Rogowski Coils"</p>
Dataset for "Personalised Learning Environments Based on Knowledge Graphs and the Zone of Proximal Development"
<p>The dataset accompanying our paper "Personalised Learning Environments Based on Knowledge Graphs and<br> the Zone of Proximal Development" published in proceedings of CSEDU 2022.</p> <p>In the dataset you will find the raw csv results from both the explorative survey and the evaluation survey.<br> <br> The surveys were made in Google Forms and the results have also been exported as pdf files that are included as well.<br> <br> Finally, screenshots of the application, grouped by module can be found inside the screenshots.zip archive.</p>
The proximity of rapeseed fields influences levels of forest damage by red deer
<p><span>We investigated the relationship between the level of red deer <em>Cervus elaphus</em> bark stripping damage in 68 Norway spruce <em>Picea abies</em> stands, and the presence of rapeseed Brassica napus fields in the surroundings, hypothesising that damage increases with decreasing distance to rapeseed fields. We also considered other potentially influencing factors, such as supplemental feeding, alternative forage availability, and deer use of spruce stands as indexed by a pellet group count.</span></p> <p><span>Bark stripping rates were measured in 68 planted stands of Norway spruce with a minimum size of 1 ha and an age interval of 20-40 years. </span><span>We selected, a priori, stands in forestry plans with a minimum of 80 % spruce. However, all stands were planted even-aged monocultures where cleaning of deciduous species had occurred at younger stages, resulting in a spruce proportion generally close to 100 %. </span><span> In each stand, 10 circular 100 m<sup>2</sup> survey plots were systematically and evenly distributed (with a random starting point). Occurrence of fresh bark-stripping damage (i.e., wounds from preceding winter) was noted for the 10 spruce stems closest to the plot centre (i.e., 100 spruce stems per stand). We measured the distance from the rapeseed fields and feeding stations to the spruce stands by using QGIS. </span></p> <p><span>An index of relative forage availability was measured by estimating percent living vegetation cover of woody browse projected onto the horizontal plane in 20 m2 subplots within targeted stands (the same 10 plots per stand as for the damage survey) and in the surrounding landscape in plots distributed along 500 m transects, one in each of the cardinal directions from the targeted stand (plots distributed at 0, 100, 200, 300, 400, and 500 m from the stand edge (0 m) making a total of 24 transect plots per stand).</span></p> <p><span>The number of red deer pellet groups were counted within targeted spruce stands and in the surrounding landscape to provide indices of relative deer stand usage and overall abundance respectively. Pellet groups were surveyed in 100 m2 circular plots within the stands (the same plots as for damage and forage survey) and in the transect plots used for forage survey described above. Only fresh (from preceding winter) pellet groups were counted.</span></p> <p><span>Spruce stands closer to rapeseed had a significantly higher proportion of damaged stems. The increased level of bark stripping damage was not explained by a higher deer stand use closer to rapeseed fields. Spruce stands closer to supplemental feeding stations had significantly higher damage levels. Damage levels were negatively related to the amount of available browse in the forest. </span></p>
Agronomy MDPI 2022 - Supplementary Materials; Proximate chemical analyses for soil, post-harvest soils, and fertilizers
<p>Supplementary Materials (Soil, Post-harvest Soils, and Fertilizers proximate chemical analyses) for the review process in Agronomy MDPI 2022. </p>
Proximate Chemical Analyses for BSFF, CHCF, NPK151515, Soil, and Post-harvest Soils - ASD_INRAE 2022
<p>Proximate chemical analyses for all tested fertilizers (BSFF, CHCF, and NPK151515), the top-soil as the potting medium gathered from Universiti Sains Malaysia (USM) Plant House L14 Building, and all the post-harvest soils after the implementations of all fertilizers (BSFF, CHCF, and NPK151515), including Control Treatment/No Fertilizer application. </p>
Proximate Chemical Analyses of Black Soldier Fly Frass (BSFF), Common House Cricket Frass (CHCF), and NPK 15:15:15 Granulated Slow-Release Fertilizers, Universiti Sains Malaysia Plant House Top Soil, and all Post-harvest Soils of applied Fertilizers.
<p>Proximate Chemical Analyses of Black Soldier Fly Frass (BSFF), Common House Cricket Frass (CHCF), and NPK 15:15:15 Granulated Slow-Release Fertilizers, Universiti Sains Malaysia Plant House Top Soil, and all Post-harvest Soils of applied Fertilizers. </p>
Proximity labeling of tau interactions in primary neurons and mouse brain
<p><span>Microtubule-associated protein tau is a central factor in Alzheimer's disease and other tauopathies. However, physiological functions of tau are unclear. Here, we used proximity labelling proteomics to chart functional tau interactomes in primary neurons and mouse brai<span>n <span>in vivo</span></span><span>. Here, we use proximity labelling with the biotin ligase BioID2 to map interactomes of tau in neurons. Data sets relate to mass spectrometry and protein identification of biotinylated proteins in primary neurons and in mouse brain after delivery of BioID2-tau fusion protein or BioID2 control protein by adeno-associated virus (AAV). Mouse brain samples are either from P35 wild-type mice with intracranial AAV delivery at P0 or from tau knockout mice at P60 after hippocampal delivery of AAV. Details on BioID2 fusion protein expression, biotin supplementation and sample extraction can be obtained in the associated publication.<br></span></span></p>
Dataset of "Giant gate-controlled odd-parity magnetoresistance in one-dimensional channels with a magnetic proximity effect"
<p>According to Onsager’s principle, electrical resistance <em>R</em> of general conductors behaves as an even function of external magnetic field <em>B</em>. Only in special circumstances, which involve time reversal symmetry (TRS) broken by ferromagnetism, the odd component of <em>R</em> against <em>B</em> is observed. This unusual phenomenon, called odd-parity magnetoresistance (OMR), was hitherto subtle (< 2%) and hard to control by external means. Here, we report a giant OMR as large as 27% in edge transport channels of an InAs quantum well, which is magnetized by a proximity effect from an underlying ferromagnetic semiconductor (Ga,Fe)Sb layer. Combining experimental results and theoretical analysis using the linearized Boltzmann’s equation, we found that simultaneous breaking of both the TRS by the magnetic proximity effect (MPE) and spatial inversion symmetry (SIS) in the one-dimensional (1D) InAs edge channels is the origin of this giant OMR. We also demonstrated the ability to turn on and off the OMR using electrical gating of either TRS or SIS in the edge channels. These findings provide a deep insight into the 1D semiconducting system with a strong magnetic coupling.</p>
Extracted data for meta-analysis: Distal versus proximal radial access in coronary angiography
<p>Data base underlying quantitative meta-analysis in the manuscript titled "Distal versus proximal radial access in coronary angiography: A meta-analysis" by Lueg, Schulze, Stöhr, & Leistner.</p> <p>Data allows meta-analysis of primary endpoint (RAO), secondary endpoints, meta-regression for moderator analysis, and publication bias analysis.</p>
Surface dust coverages on rock targets in Gale crater: Influence of seasonal wind variability, elevation and proximity to aeolian sand fields.
<p>The following dataset accompanies the paper submission to AGU - JGR: Planets for the paper titled: "</p> <p><span>Surface dust coverages on rock targets in Gale crater: Influence of seasonal wind variability, elevation and proximity to aeolian sand fields."</span></p>
Fig 4 in Proximate composition and its seasonal variations of the muscle tissue of Channa striata from Krishna river, Andhra Pradesh
Fig 4: Ash content variations in muscle of male and female C. striata
Fig 2 in Proximate composition and its seasonal variations of the muscle tissue of Channa striata from Krishna river, Andhra Pradesh
Fig 2: Fat content variations in muscle of male and female C. striata
Fig 3 in Proximate composition and its seasonal variations of the muscle tissue of Channa striata from Krishna river, Andhra Pradesh
Fig 3: Moisture content variations in muscle of male and female C. striata
Fig 1 in Proximate composition and its seasonal variations of the muscle tissue of Channa striata from Krishna river, Andhra Pradesh
Fig 1: Protein content variations in muscle of male and female C. striata
Close encounters between infants and household members measured through wearable proximity sensors
<p>The dataset contains close proximity interactions between family members of 16 households with infants younger than 6 months, recorded for 2-5 consecutive days between March 2015 and January 2016, in Rome, Italy. Data were collected trough the use of wearable proximity sensors of the SocioPatterns platform (<a href="http://sociopatterns.org">http://sociopatterns.org</a>).</p> <p>Contact events were recorded between 55 individuals: 16 infants, 4 siblings, 31 parents and 4 grandparents.</p> <p>Each line of the dataset corresponds to a contact event recorded between two sensors (sensor 1 and sensor 2). Heading labels are the following:</p> <ul> <li>ID_sensor1: anonymized ID of sensor 1;</li> <li>ID_sensor2: anonymized ID of sensor 2;</li> <li>contact_duration: duration of the contact event in seconds;</li> <li>time: date and time of the contact event;</li> <li>family_role_tag1: family role of individual wearing sensor 1;</li> <li>Household: household ID;</li> <li>family_role_tag2: family role of individual wearing sensor 2.</li> </ul> <p> </p>
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Allen Brain Atlas
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International Brain Laboratory public data
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OpenNeuro
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