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236
datasets available to search
ShareScore release 0.9.0
Dataset results
236 results for “active site”
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells [4C-seq]
GEO Series GSE97803. Mus musculus. 6 samples. Type: Other.
Genome-wide identification of HIF-1 and HIF-2 binding sites in hypoxic human macrophages alternatively activated by IL-10
GEO Series GSE56989. Homo sapiens. 36 samples. Type: Expression profiling by array.
N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas
GEO Series GSE62690. Chlamydomonas reinhardtii. 14 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing.
Set1/COMPASS repels heterochromatin invasion at euchromatic sites by disrupting Suv39/Clr4 activity and nucleosome stability
GEO Series GSE140067. Schizosaccharomyces pombe. 16 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
The human β-globin enhancer LCR HS2 plays a role in forming a TAD by activating chromatin structure at neighboring CTCF sites
GEO Series GSE159130. Mus musculus. 8 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Prp4 Kinase Grants the License to Splice: Control of Weak Splice Sites during Spliceosome Activation
GEO Series GSE75517. Schizosaccharomyces pombe. 3 samples. Type: Expression profiling by high throughput sequencing; Other.
Combination Targeting of the Bromodomain and Acetyltransferase Active Site of p300/CBP [ChIP-seq]
GEO Series GSE124642. Homo sapiens. 10 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
DNA accessibility sites requiring SMARCA4 activity in neuroblastoma cells [ATAC-seq]
GEO Series GSE190706. Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Knockdown of GRHL2 affects active enhancers (H3K27ac sites) enriched for ER binding
GEO Series GSE123475. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells [RNA-seq]
GEO Series GSE92931. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.
Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells
GEO Series GSE92932. Mus musculus. 37 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes
GEO Series GSE180566. Homo sapiens. 146 samples. Type: Other.
Aspartate Residues Far From the Active Site Drive O-GlcNAc Transferase Substrate Selection
GEO Series GSE132205. Homo sapiens. 15 samples. Type: Protein profiling by protein array.
Pioneer activity distinguishes activating from non-activating SOX2 binding sites [ChIP-Seq]
GEO Series GSE234703. Mus musculus. 11 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Selective ligand removal to improve accessibility of active sites in hierarchical MOFs for heterogeneous photocatalysis
<p>This file includes the source data for all experimental and theoretical data of the publication.</p>
Molecular Dynamics simulation data for the article "Evolution of cation binding in the active sites of P-loop nucleoside triphosphatases in relation to the basic catalytic mechanism"
<p>Zipped archives with MD simulation data for the article "Evolution of cation binding in the active sites of P-loop nucleoside triphosphatases in relation to the basic catalytic mechanism" (eLife, accepted).</p>
Fig. 6. The V19H four-point mutant retained V19H activity and gained T3O-like activity. Recombinant yeast expressing different V19H in Site directed mutagenesis of Catharanthus roseus (+)-vincadifformine 19-hydroxylase (CYP71BY3) results in two distinct enzymatic functions
Fig. 6. The V19H four-point mutant retained V19H activity and gained T3O-like activity. Recombinant yeast expressing different V19H mutants were incubated with (+)-vincadifformine (15) (A) or with ()-tabersonine (1) (B) and reaction products were submitted to UPLV-MS analysis. Traces from yeast expressing the V19H single mutants (orange), from top to bottom, are V19H-L106R, V19H–S312T, V19H-A376P, and V19H–F377L. Traces from yeast expressing the V19H double mutant (pink) is V19H- A376P–F377L, and the 4-point mutant (red) is V19HL106R–S312T-A376P–F377L. Yeast expressing wildtype V19H (green) and wild-type T3O (blue) were used as positive controls for (+)-minovincinine (15) (A) and tabersonine-2,3-epoxide (5) (B) biosynthesis. All V19H mutants retain V19H activity, producing (+)-minovincinine (16) from (+)-vincadifformine (15) (A: orange, pink, and red), but the V19H 4-point mutant gained T3O-like activity, producing tabersonine-2,3-epoxide (5) from ()-tabersonine (1) (B: red). V19H: (+)-vincadifformine 19-hydroxylase; T3O: tabersonine 3-oxygenase. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)
Evaluation of Anti-Xa Activity in Patients With Severe Obesity After Subcutaneous Injection of Enoxaparin for Antithrombotic Prophylaxis at Two Different Sites.
ClinicalTrials.gov study NCT07213713. IPD Sharing: NO. Countries: 0. Publications: 0.
DNA accessibility sites requiring SWI/SNF or β-catenin activity [ATAC-seq]
GEO Series GSE260866. Homo sapiens. 13 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
H3K9 trimethylation in active compartments optimizes stimulus-regulated transcription by restricting usage of CTCF sites in SINE-B2 repeats [ChIP-Seq]
GEO Series GSE189971. Mus musculus. 36 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.