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4,495
datasets available to search
ShareScore release 0.9.0
Dataset results
4,495 results for “clinical evaluation”
ASSURE WCD Clinical Evaluation - Conversion Efficacy Study
ClinicalTrials.gov study NCT04132466. IPD Sharing: NO. Countries: 1. Publications: 1.
Clinical Study for Safety and Acute Performance Evaluation of the THERMOCOOL SMARTTOUCH® SF-5D System Used With Fast Ablation Mode in Treatment of Patients With Paroxysmal Atrial Fibrillation.
ClinicalTrials.gov study NCT03459196. IPD Sharing: Not stated. Countries: 4. Publications: 1.
Clinical Evaluation of the Safety and Efficacy of a 1060nm Diode Laser (Abdomen)
ClinicalTrials.gov study NCT03756350. IPD Sharing: NO. Countries: 1. Publications: 4.
Evaluation of a "Fast Track" Respiratory Therapy Clinic for Patients With Suspected Severe Sleep-Disordered Breathing
ClinicalTrials.gov study NCT02191085. IPD Sharing: NO. Countries: 1. Publications: 12.
A Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of PGDM1400LS Alone and in Combination With VRC07-523LS and PGT121.414.LS in Healthy, HIV-uninfected Adult Participants
ClinicalTrials.gov study NCT05184452. IPD Sharing: NO. Countries: 4. Publications: 1.
Clinical Trial to Evaluate the Efficacy and Safety of Fesoterodine in Comparison to Tolterodine Extended Release(ER)in Patients With Overactive Bladder.
ClinicalTrials.gov study NCT00611026. IPD Sharing: Not stated. Countries: 25. Publications: 2.
Clinical Evaluation of Eltrombopag in Chronic Idiopathic Thrombocytopenic Purpura (ITP)
ClinicalTrials.gov study NCT00828750. IPD Sharing: Not stated. Countries: 1. Publications: 1.
A Clinical Study to Evaluate the Use of Episodic, Intensive Blood Glucose Monitoring in Persons With Non-insulin Treated Type 2 Diabetes
ClinicalTrials.gov study NCT00674986. IPD Sharing: Not stated. Countries: 1. Publications: 3.
SecuraTM ICD Clinical Evaluation Study
ClinicalTrials.gov study NCT00526227. IPD Sharing: Not stated. Countries: 7. Publications: 1.
Trial to Evaluate the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis
ClinicalTrials.gov study NCT04657666. IPD Sharing: NO. Countries: 2. Publications: 1.
Clinical Study to Evaluate the Efficacy and Safety of Three Different Doses of BAY1817080 Compared to Placebo in Patients With Chronic Cough
ClinicalTrials.gov study NCT04562155. IPD Sharing: NO. Countries: 19. Publications: 3.
A Clinical Trial to Evaluate the Safety and Immunogenicity of BG505 MD39.3, BG505 MD39.3 gp151, and BG505 MD39.3 gp151 CD4KO HIV Trimer mRNA Vaccines in Healthy, HIV-uninfected Adult Participants
ClinicalTrials.gov study NCT05217641. IPD Sharing: NO. Countries: 1. Publications: 1.
DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adu
ClinicalTrials.gov study NCT05415722. IPD Sharing: NO. Countries: 1. Publications: 1.
A Clinical Trial to Evaluate a Corneal Inlay for the Improvement of Near Vision in Presbyopic Patients
ClinicalTrials.gov study NCT01373580. IPD Sharing: NO. Countries: 1. Publications: 1.
A Phase 3 Clinical Trial to Evaluate the Safety and Efficacy of Ensifentrine in Patients With COPD
ClinicalTrials.gov study NCT04535986. IPD Sharing: Not stated. Countries: 12. Publications: 4.
AVJ-301 Clinical Trial: A Clinical Evaluation of AVJ-301 (Absorb™ BVS) in Japanese Population
ClinicalTrials.gov study NCT01844284. IPD Sharing: Not stated. Countries: 1. Publications: 8.
A Clinical Trial to Evaluate AZD7648 Alone and in Combination With Other Anti-cancer Agents in Patients With Advanced Cancers.
ClinicalTrials.gov study NCT03907969. IPD Sharing: YES. Countries: 2. Publications: 1.
Validation of Sepsis-3 using survival analysis and clinical evaluation of quick SOFA, SIRS, and burn-specific SIRS for sepsis in burn patients with suspected infection
Open the record for dataset details and reuse information.
Data from: Evaluating culture-free targeted next-generation sequencing for diagnosing drug-resistant tuberculosis: A multicentre clinical study of two end-to-end commercial workflows
Open the record for dataset details and reuse information.
Clinical and genomic evaluation of 207 genetic myopathies in the Indian subcontinent
Objective <p>Inherited myopathies comprise more than 200 different individually rare disease-subtypes but when combined together have a high prevalence of 1 in 6000 individuals across the world. Our goal was to determine for the first time the clinical- and gene-variant spectrum of genetic myopathies in a substantial cohort study of the Indian subcontinent.</p> Methods <p>In this cohort-study, we performed the first large clinical exome sequencing (ES) study with phenotype correlation on 207 clinically well-characterized inherited myopathy-suspected patients from the Indian subcontinent with diverse ethnicities.</p> Results <p>Clinical-correlation driven definitive molecular diagnosis was established in 49% (101 cases; 95% CI, 42%-56%) of patients with the major contributing pathogenicity in either of three genes, <i>GNE </i>(28%; GNE-myopathy), <i>DYSF </i>(25%; Dysferlinopathy) and <i>CAPN3 </i>(19%; Calpainopathy). We identified 65 variant alleles comprising 37 unique variants in these three major genes. 78% of the <i>DYSF</i> patients were homozygous for the detected pathogenic variant suggesting the need for carrier-testing for autosomal-recessive disorders like Dysferlinopathy that are common in India. We describe the observed clinical spectrum of myopathies including uncommon and rare subtypes in India: Sarcoglycanopathies (<i>SGCA/B/D/G</i>), Collagenopathy (<i>COL6A1/2/3</i>), Anoctaminopathy (<i>ANO5</i>), telethoninopathy (<i>TCAP</i>), Pompe-disease (<i>GAA</i>), Myoadenylate-deaminase-deficiency-myopathy (<i>AMPD1</i>), myotilinopathy (<i>MYOT</i>), laminopathy (<i>LMNA</i>), HSP40-proteinopathy (<i>DNAJB6</i>), Emery-Dreifuss-muscular-dystrophy (<i>EMD</i>), Filaminopathy (<i>FLNC</i>), TRIM32-proteinopathy (<i>TRIM32</i>), POMT1-proteinopathy (<i>POMT1</i>), and Merosin-deficiency-congenital-muscular-dystrophy-type-1 (<i>LAMA2</i>). 13 Patients harbored pathogenic variants in >1 gene and had unusual clinical features suggesting a possible role of synergistic-heterozygosity / digenic-contribution to disease presentation and progression.</p> Conclusions <p>Application of clinically-correlated ES to myopathy diagnosis has improved our understanding of the clinical and genetic spectrum of different subtypes and their overlaps in Indian patients. This, in turn, will enhance the global gene-variant-disease databases by including data from developing countries/continents for more efficient clinically-driven molecular diagnostics.</p>
ScienceDex guides
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
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DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.