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318 results for “direct development”
Data from: Phylogenomic support for evolutionary relationships of New World direct-developing frogs (Anura: Terraranae)
Phylogenomic approaches have proven able to resolve difficult branches in the tree of life. New World direct-developing frogs (Terraranae) represent a large evolutionary radiation in which interrelationships at key points in the phylogeny have not been adequately determined, affecting evolutionary, biogeographic, and taxonomic interpretations. We employed anchored hybrid enrichment to generate a data set containing 389 loci and >600,000 nucleotide positions for 30 terraranan and several outgroup frog species encompassing all major lineages in the clade. Concatenated maximum likelihood and coalescent species-tree approaches recover nearly identical topologies with strong support for nearly all relationships in the tree. These results are similar to previous phylogenetic results but provide additional resolution at short internodes. Among taxa whose placement varied in previous analyses, Ceuthomantis is shown to be the sister taxon to all other terraranans, rather than deeply embedded within the radiation, and Strabomantidae is monophyletic rather than paraphyletic with respect to Craugastoridae. We present an updated taxonomy to reflect these results, and describe a new subfamily for the genus Hypodactylus.
Direct Intraocular Lens Extraction Using a Newly Developed Lens-Grabbing Forceps
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Figure 3 in Reproductive biology of direct developing and threatened frog Adelophryne maranguapensis (Anura, Eleutherodactylidae) reveals a cryptic reproductive mode for anurans and the first record of parental care for the genus
Figure 3. Female Adelophryne maranguapensis showing parental care activity (clutch 13, Table 1).
Figure 1 in Reproductive biology of direct developing and threatened frog Adelophryne maranguapensis (Anura, Eleutherodactylidae) reveals a cryptic reproductive mode for anurans and the first record of parental care for the genus
Figure 1. Fieldwork areas. Riacho Beija-flor (a) and Pico da Rajada (b).
Supplemental material from: Can transcranial direct current stimulation enhance post-stroke motor recovery? Development of a theoretical patient-tailored model
<p>New treatments that can facilitate neural repair and reduce persistent impairments have significant value in promoting recovery following stroke. One technique that has gained interest is transcranial direct current stimulation (tDCS) as early research suggested it could enhance plasticity and enable greater behavioral recovery. However, several studies have now identified substantial inter-subject variability in response to tDCS and clinical trials revealed insufficient evidence of treatment effectiveness. A possible explanation for the varied and negative findings is that the physiological model of stroke recovery that researchers have used to guide the application of tDCS based treatments in stroke is overly simplistic and does not account for stroke heterogeneity or known determinants that affect the tDCS response. <a name="_Hlk62139152">Here, we propose that tDCS could have a more clearly beneficial role in enhancing stroke recovery</a> if greater consideration is given to individualizing treatment. By critically reviewing the proposed mechanisms of tDCS, stroke physiology across the recovery continuum, and known determinants of tDCS response, we propose a new, theoretical, patient-tailored approach to delivering tDCS after stroke. The proposed model includes a step-by-step principled selection strategy for identifying optimal neuromodulation targets and outlines key areas for further investigation. Tailoring tDCS treatment to individual neuroanatomy and physiology is likely our best chance at producing robust and meaningful clinical benefit for people with stroke and would, therefore, accelerate opportunities for clinical translation.</p>
Figure 1a from: Ioanas H, Saab B, Rudin M (2017) Gentoo Linux for Neuroscience - a replicable, flexible, scalable, rolling-release environment that provides direct access to development software. Research Ideas and Outcomes 3: e12095. https://doi.org/10.3897/rio.3.e12095
Figure 1a - Minimal (excluding all optional features) dependency graph of the contributed neuroscience package set.
Figure 1b from: Ioanas H, Saab B, Rudin M (2017) Gentoo Linux for Neuroscience - a replicable, flexible, scalable, rolling-release environment that provides direct access to development software. Research Ideas and Outcomes 3: e12095. https://doi.org/10.3897/rio.3.e12095
Figure 1b - Maximal (including all optional features) dependency graph of the contributed neuroscience package set.
SPECIAL DIRECTIONS OF DEVELOPMENT OF PILGRIMAGE TOURISM IN OUR COUNTRY
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Data from: Inflorescence and flower development in Musa velutina H. Wendl. & Drude (Musaceae), with a consideration of developmental variability, restricted phyllotactic direction, and hand initiation
Premise of research. Inflorescence and flower structure in the Musaceae is unique in the Zingiberales. The inflorescence lacks the obvious cincinnus structure that characterizes the order, and the flowers are unisexual. Previous studies were conducted using cultivated varieties and were carried out with sectioned material, which does not permit accurate developmental descriptions. Developmental study of a wild species with modern methods addresses these shortcomings and provides more accurate descriptions. Methodology. Young inflorescences and flowers were collected from botanical gardens in Hawaii and Australia and critical-point dried for observation with a scanning electron microscope. Pivotal results. All shoots and inflorescences have sinistrorse (left-handed) phyllotaxy, and the sequence of flower initiation is usually correlated with this pattern. Initiation begins on the cathodic side of the hand (opposite the direction of phyllotactic rise) and progresses anodically (in the direction of phyllotactic rise). Within this general pattern, the sequence of flower initiation is variable, even within the same inflorescence. Five patterns of initiation are reported, with additional variation within each pattern. Both male and female flowers have similar early developmental patterns but diverge at the time of petal/inner androecial formation. In male flowers the anterior side of the flower develops slightly ahead of the posterior, while in female flowers the posterior side develops slightly ahead of the anterior. While consistently present in the material analyzed here, these differences are not apparent at the time of gynoecial initiation or in the mature flowers. Conclusions. The banana inflorescence is another example of how higher-level phyllotactic patterns can influence the sequence of organ initiation at lower levels. Despite variability in the sequence of flower initiation in a hand, the best interpretation of the hand remains a cincinnus. Variability in inflorescence and floral development is rarely reported and may be more common than currently supposed.
FIGURE 30 in New World direct-developing frogs (Anura: Terrarana): Molecular phylogeny, classification, biogeography, and conservation
FIGURE 30. Diasporus diastema from Cerro La Campana, Panama, Panama. Photo by W. E. Duellman.
FIGURE 25 in New World direct-developing frogs (Anura: Terrarana): Molecular phylogeny, classification, biogeography, and conservation
FIGURE 25. Distribution of the Subgenus Hylactophryne, Genus Craugastor, Family Craugastoridae.
FIGURE 28 in New World direct-developing frogs (Anura: Terrarana): Molecular phylogeny, classification, biogeography, and conservation
FIGURE 28. Haddadus binotatus from Pisinguaba, São Paulo, Brazil. Photo by C. F. B. Haddad.
FIGURE 5 in New World direct-developing frogs (Anura: Terrarana): Molecular phylogeny, classification, biogeography, and conservation
FIGURE 5. Distribution of the taxon Terrarana.
Figure 2 in Direct development of the bush frog Raorchestes longchuanensis (Yang and Li 1978) under laborary conditions in Southern China
Figure 2. Raorchestes longchuanensis, in nature from Yinjiang, Yunnan, China.
Epigenetic Changes in Hepatocellular Carcinoma Developed After Direct Acting Antiviral Therapy for Chronic Hepatitis C
ClinicalTrials.gov study NCT04220151. IPD Sharing: NO. Countries: 0. Publications: 4.
Data from: Phylogenomic support for evolutionary relationships of New World direct-developing frogs (Anura: Terraranae)
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Supplemental material from: Can transcranial direct current stimulation enhance post-stroke motor recovery? Development of a theoretical patient-tailored model
Open the record for dataset details and reuse information.
Data from: Inflorescence and flower development in Musa velutina H. Wendl. & Drude (Musaceae), with a consideration of developmental variability, restricted phyllotactic direction, and hand initiation
Open the record for dataset details and reuse information.
Interleukin-17 directly stimulates tumor infiltrating Tregs to prevent cancer development [scRNA-seq]
GEO Series GSE262405. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Chip-on-chip analysis of direct Nkx2.1 target genes in proliferating and differentiating epithelium in mouse lung development.
GEO Series GSE23043. Mus musculus. 10 samples. Type: Genome binding/occupancy profiling by array.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.