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213
datasets available to search
ShareScore release 0.9.0
Dataset results
213 results for “drug screening”
Drug screening and genomic analyses of HER2 positive breast cancer cell lines reveal predictors for treatment response [CGH]
GEO Series GSE58886. Homo sapiens. 4 samples. Type: Genome variation profiling by genome tiling array.
Discovery of a drug targeting microenvironmental support for lymphoma cells by screening using patient-derived xenograft cells
GEO Series GSE71944. Homo sapiens; Mus musculus. 11 samples. Type: Expression profiling by array.
Integrated transcriptomic and in silico drug screening identifies potential stroma-targeting therapeutics in pancreatic cancer
GEO Series GSE196524. Homo sapiens. 48 samples. Type: Expression profiling by array.
Deconvolution of drug screening data delineates drug sensitivity of stem-like cancer cells in Acute Myeloid Leukemia
GEO Series GSE217924. Homo sapiens. 11 samples. Type: Expression profiling by high throughput sequencing.
Developing novel flavonoid senolytics through phenotypic drug screening and drug design
GEO Series GSE279349. Mus musculus. 36 samples. Type: Expression profiling by high throughput sequencing.
Gene Signature-guided Drug Screening Identified Narciclasine as a Potential Therapeutic Drug for Renal Interstitial Fibrosis
GEO Series GSE269356. Mus musculus; Rattus norvegicus. 18 samples. Type: Expression profiling by high throughput sequencing.
Drug screening in Drosophila for repurposing in neuropsychiatry
GEO Series GSE142384. Drosophila melanogaster. 58 samples. Type: Expression profiling by array.
A cell competition-based drug screen identifies a novel compound that targets c-Myc addiction of leukemia cells
GEO Series GSE100678. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Drug-induced hepatotoxicity screening in primary mouse hepatocytes, an Omics approach.
GEO Series GSE33742. Mus musculus. 6 samples. Type: Expression profiling by array.
Probabilistic modeling of personalized drug combinations from integrated chemical screen and molecular data in sarcoma
DNA and RNA were isolated from snap frozen primary tumor tissue (human and mouse), and DNA was isolated from matched normal tissue (region matched non-tumor tissue for human, tail section for mouse). A mouse leg was also injected with cardiotoxin to induce tissue damage was taken following sacrifice and was snap frozen, then processed for RNA isolation to serve as a mouse tissue-normal for RNA sequencing. All sequencing was performed at the OHSU MPSSR core.
Datasets for training and for testing ligand-based reverse screening to predict drug targets.
<p>Bioactivity data were obtained from the ChEMBL (version 25) and the Reaxys<sup>®</sup> (version 03.2019) databases for training/screening and testing target prediction of small molecule drug by reverse screening. A short extract of the raw ChEMBL data for training is given in <strong>Supplementary Table 1 </strong>(Supp_Table_1.xlsx) to show three lines corresponding to an active, an inactive and an ‘gray area’ datapoints, respectively. Processed data are deposited here. The screening set file contains (CHEMBL-screeningset.csv), for each active compound, the standardized SMILES, the ChEMBLID, the number of experimental target(s) and their UniProt identifier(s). The test set file (Reaxys-testset-with300-SMILES.csv) contains, for each 364201 active compound, the ReaxysID, the number of experimental target(s) and the UniProt identifier(s). For Reaxys users, the chemical structure can be obtained through bulk request on the website. Access to www.reaxys.com and to Reaxys data can be obtained by contacting Elsevier directly. The first 300 entries display the standardized SMILES so that every reader can reproduce the results obtained by the reverse screening exercise.</p> <p>Further datasets can be obtained at www.swisstargetprediction.ch/download.php</p>
Drug screening and genomic analyses of HER2 positive breast cancer cell lines reveal predictors for treatment response [Expression profiling]
GEO Series GSE58700. Homo sapiens. 13 samples. Type: Expression profiling by array.
WP5.3 Screening drug molecule that inhibit iron transport
<p>TXTL reaction</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.