Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
965
datasets available to search
ShareScore release 0.9.0
Dataset results
965 results for “placentation”
Data from: Association of in utero persistent organic pollutant exposure with placental thyroid hormones
In utero exposure to persistent organic pollutants (POPs) can result in thyroid function disorder, leading to concerns about their impact on fetal and neonatal development. The present study was performed to investigate the associations between placental levels of various POPs and thyroid hormones (THs). In a prospective Danish study initially established for assessing congenital cryptorchidism, 58 placenta samples were collected from mothers of boys born with (28) and without (30) cryptorchidism. The concentrations of polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins/furans (PCDD/Fs), organotin chemicals (OTCs), organochlorine pesticides (OCPs), thyroxine (T4), 3,3',5-triiodothyronine (T3), and 3,3',5'-triiodothyronine (rT3) were measured. The associations between placental THs and various POPs were analyzed using multiple linear regression. Five PBDEs, 35 PCBs, 14 PCDD/Fs, 3 OTCs, 25 OCPs, T4, T3, and rT3 were measured. No correlation between THs and the odds of cryptorchidism was found. Several POPs were significantly associated with THs: a) T4 was inversely associated with BDEs 99, 100, ΣPBDE, and 2378-TeCDD, and positively associated with 1234678-HpCDF; b) T3 was positively associated with 2378-TeCDF and 12378-PeCDF; c) rT3 was positively associated with PCB 81, 12378-PeCDF and 234678-HxCDF, and inversely associated with tributyltin (TBT), ΣOTC, and methoxychlor (MOC). These results revealed that POP exposures were associated with TH levels in placenta, a possible mechanism for the impacts of POP exposures on children's growth and development. This study provides new insight into the complexity of thyroid-disrupting properties of POPs. More research is needed to elucidate the biological consequences of POP exposures.
Histological and life history data for small-bodied mammals from: Multituberculate mammals show evidence of a life history strategy similar to that of placentals, not marsupials
<p>The remarkable evolutionary success of placental mammals has been partly attributed to their reproductive strategy of prolonged gestation and birthing of relatively precocial, quickly weaned neonates. Although this strategy was conventionally considered derived relative to that of marsupials with highly altricial neonates and long lactation periods, mounting evidence has challenged this view. Until now, the fossil record has been relatively silent on this debate, but here we find that proportions of different bone tissue microstructures in the femoral cortices of small extant marsupials and placentals correlate with length of lactation period, allowing us to apply this histological correlate of reproductive strategies to Late Cretaceous and Paleocene members of Multituberculata, an extinct mammalian clade that is phylogenetically stemward of Theria. Multituberculate bone histology closely resembles that of placentals, suggesting that they had similar life history strategies. That a stem-therian clade exhibits evidence of placental-like life histories supports the hypothesis that intense maternal-fetal contact characteristic of placentals is ancestral for therians. Alternatively, multituberculates and placentals may have independently evolved prolonged gestation and abbreviated lactation periods. Our results challenge the hypothesis that the rise of placental mammals was driven by unique life history innovations, and shed new light on early mammalian diversification.</p>
ZIKV in situ hybridization from full thickness placental center cuts, only positive samples included
<p>These data accompany the manuscript "Infection of the maternal-fetal interface and vertical transmission following low-dose inoculation of pregnant rhesus macaques (<em>Macaca mulattta</em>) with an African-lineage Zika virus" The included images are low magnification scans of full-thickness placental sections (placenta containing decidua, placental villi, and chorionic plate) evaluated with in situ hybridization against ZIKV RNA. Details of methods are provided in the manuscript. Only slides that were deemed positive are included. </p>
Human placental MeRIP-seq data-Input
<p>MeRIP-seq for huamn placental tissues from different gestational age. Early, first trimester; Middle, second trimester; Late, third trimester. </p>
Figure 3 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 3. Mandible shape variation along the first three relative warps (RW). A, relative warp 1 versus 3 showing the distribution of diet classes; B, relative warp 2 versus 3 showing the distribution of diet classes; C, relative warp 1 versus 3, showing the distribution of taxonomic groups; D, relative warp 2 versus 3, showing the distribution of taxonomic groups. Shape reconstructions show the extreme shape of each RW in black lines against the consensus shape in grey lines.
Figure 2 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 2. Mandible shape variation along the first four relative warps (RW). A, relative warp 1 versus 2, showing the distribution of diet classes; B, relative warp 3 versus 4, showing the distribution of diet classes; C, relative warp 1 versus 2, showing the distribution of taxonomic groups; D, relative warp 3 versus 4, showing the distribution of taxonomic groups. Shape reconstructions show the extreme shape of each RW in black lines against the consensus shape in grey lines.
Figure 1 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 1. Lateral view of a Canis lupus mandible showing the landmarks and semilandmarks used. Squares, landmarks; X, semilandmarks; 1, caudal extreme of the condyle; 2, most concave point of the mandibular notch; 3, dorso-caudal angle of the coronoid process; 4–11, semilandmarks; 12, distal extreme of the lower carnassial; 13, distal border of the protoconid projected to the base of the crown; 14, mesial border of the lower carnassial; 15, distal extreme of the c1; 16, mesial extreme of the c1; 17–28, semilandmarks; 29, anterior border of the masseteric fosa.
Figure 5 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 5. Canonical analysis of variance of taxonomic groups and diet classes. A, dietary discrimination in marsupials (factor 1 versus 2); B, discrimination of main Carnivora clades (factor 1 versus 2); C, discrimination of main Caniformia clades (factor 1 versus 2); D, discrimination of main Feliformia clades (factor 1 versus 2). Shape reconstructions show the extreme shape of each RW in black lines against the consensus shape in grey lines.
Figure 7 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 7. Allometric relationship between mandible shape and size. Consensus configuration is in the middle, shape of the largest species (Ursus arctos) to the left, and shape of the smallest species (Planigale maculate) to the right.
Figure 6 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 6. Canonical analysis of variance of taxonomic groups. A, Methateria (light grey) versus Carnivora (dark grey); B, Caniformia (dark grey) versus Feliformia (light grey).
Figure 4 in Mandible shape in marsupial and placental carnivorous mammals: a morphological comparative study using geometric morphometrics
Figure 4. Canonical analysis of variance of diet classes. A, factor 1 versus 2; B: factor 1 versus 3. Shape reconstructions show the extreme shape of each RW in black lines against the consensus shape in grey lines.
Unequal Placental Sharing in Monochorionic Diamniotic Twins: an Observational Study
ClinicalTrials.gov study NCT03024918. IPD Sharing: UNDECIDED. Countries: 1. Publications: 31.
Extrauterine Placental Transfusion In Neonatal Resuscitation Of Very Low Birth Weight Infants
ClinicalTrials.gov study NCT03916159. IPD Sharing: NO. Countries: 1. Publications: 3.
Effect of Delayed Cord Clamping in Preterm Neonates With Placental Insufficiency
ClinicalTrials.gov study NCT03731546. IPD Sharing: NO. Countries: 1. Publications: 3.
Malaria Rapid Diagnostic Tests (RDTs) in Pregnancy: Detection of Placental Malaria
ClinicalTrials.gov study NCT01555255. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Evaluation of a Novel Diagnostic Kit for the Detection of Placental Alpha-Microglobulin-1 in the Prediction of Preterm Birth
ClinicalTrials.gov study NCT02092688. IPD Sharing: Not stated. Countries: 1. Publications: 6.
The Efficacy of a Temporary Sub-Placental Uterine Tourniquet in Minimizing Intraoperative Blood Loss in Management of Placenta Accreta Spectrum Disorder by a Retrograde Cesarean Hysterectomy (Bladder
ClinicalTrials.gov study NCT05936645. IPD Sharing: YES. Countries: 1. Publications: 9.
Antenatal Diagnosis of Placental Attachment Disorders
ClinicalTrials.gov study NCT02442518. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Balloon Catheters in Cases of Abnormal Placentation
ClinicalTrials.gov study NCT01373255. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Impact of Umbilical Cord Milking in Preterm Neonates With Placental Insufficiency
ClinicalTrials.gov study NCT03731611. IPD Sharing: NO. Countries: 1. Publications: 2.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.