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728 results for “urine”
Quick-Wee Versus Bladder Stimulation System to Collect Midstream Urine From Pre-continent Infants
ClinicalTrials.gov study NCT04587999. IPD Sharing: Not stated. Countries: 2. Publications: 1.
Efficacy Study of a Urine DEK ELISA for Diagnosis of Bladder Cancer
ClinicalTrials.gov study NCT01563796. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Diagnosis of Sport-related Concussion Using Urine Metabolites
ClinicalTrials.gov study NCT03653195. IPD Sharing: UNDECIDED. Countries: 1. Publications: 9.
The Changes of Urine Growth Factors Level
ClinicalTrials.gov study NCT06282731. IPD Sharing: NO. Countries: 1. Publications: 49.
RT-PCR on Urine Samples: Added Value for the Diagnosis of Chikungunya Virus Infection
ClinicalTrials.gov study NCT02714985. IPD Sharing: NO. Countries: 2. Publications: 10.
Effect of dapagliflozin on urine metabolome in patients with type 2 diabetes
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Data from: Direct nano-electrospray ionization tandem mass spectrometry for quantification and identification of metronidazole in its dosage form and human urine
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Urine uromodulin as a biomarker of kidney tubulointerstitial fibrosis
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Data from: Untargeted metabolomic profiling of urine from healthy dogs and dogs with chronic hepatic disease
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Raw data for Urine DNA (uDNA) as a non-lethal method for endoparasite biomonitoring: development and validation
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Data from: Urine is an important nitrogen source for plants irrespective of vegetation composition in an Arctic tundra: insights from a 15N-enriched urea tracer experiment
1. Mammalian herbivores can strongly influence nitrogen (N) cycling and herbivore urine could be a central component of the N cycle in grazed ecosystems. Despite its potential role for ecosystem productivity and functioning, the fate of N derived from urine has rarely been investigated in grazed ecosystems. 2. This study explored the fate of <sup>15</sup>N-enriched urea in tundra sites that have been either lightly or intensively grazed by reindeer for more than 50 years. We followed the fate of the <sup>15</sup>N applied to the plant canopy, at 2 weeks and 1 year after tracer addition, in the different ecosystem N pools. 3. <sup>15</sup>N-urea was rapidly incorporated in cryptogams and in aboveground parts of vascular plants, while the soil microbial pool and plant roots sequestered only a marginal proportion. Further, the litter layer constituted a large sink for the <sup>15</sup>N-urea, at least in the short term, indicating a high biological activity in the litter layer and high immobilization in the first phases of organic matter decomposition. 4. Mosses and lichens still constituted the largest sink for the <sup>15</sup>N-urea 1 year after tracer addition at both levels of grazing intensity demonstrating their large ability to capture and retain N from urine. Despite large fundamental differences in their traits, deciduous and evergreen shrubs were just as efficient as graminoids in taking up the <sup>15</sup>N-urea. The total recovery of <sup>15</sup>N-urea was lower in the intensively grazed sites, suggesting that reindeer reduce ecosystem N retention. 5. <i>Synthesis</i> The rapid incorporation of the applied <sup>15</sup>N-urea indicates that arctic plants can take advantage of a pulse of incoming N from urine. In addition, δ <sup>15</sup>N values of all taxa in the heavily grazed sites converged towards the δ <sup>15</sup>N values for urine, bringing further evidence that urine is an important N source for plants in grazed tundra ecosystems.
Data from: Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance
Toxoplasma gondii chronic infection in rodent secondary hosts has been reported to lead to a loss of innate, hard-wired fear toward cats, its primary host. However the generality of this response across T. gondii strains and the underlying mechanism for this pathogen-mediated behavioral change remain unknown. To begin exploring these questions, we evaluated the effects of infection with two previously uninvestigated isolates from the three major North American clonal lineages of T. gondii, Type III and an attenuated strain of Type I. Using an hour-long open field activity assay optimized for this purpose, we measured mouse aversion toward predator and non-predator urines. We show that loss of innate aversion of cat urine is a general trait caused by infection with any of the three major clonal lineages of parasite. Surprisingly, we found that infection with the attenuated Type I parasite results in sustained loss of aversion at times post infection when neither parasite nor ongoing brain inflammation were detectable. This suggests that T. gondii-mediated interruption of mouse innate aversion toward cat urine may occur during early acute infection in a permanent manner, not requiring persistence of parasite cysts or continuing brain inflammation.
Data from: Analytical performance, agreement and user-friendliness of six point of care testing urine analysers for urinary tract infection in general practice.
Objective: Various point-of-care testing (POCT) urine analysers are commercially available for routine urine analysis in general practice. The present study compares analytical performance, agreement and user-friendliness of six different POCT urine analysers for diagnosing urinary tract infection in general practice. Setting: All testing procedures were performed at a diagnostic centre for primary care in the Netherlands. Urine samples were collected at four general practices. Primary and secondary outcome measures: Analytical performance and agreement of the POCT analysers regarding nitrite, leucocytes and erythrocytes, with the laboratory reference standard, was the primary outcome measure, and analysed by calculating sensitivity, specificity, positive and negative predictive value, and Cohen's κ coefficient for agreement. Secondary outcome measures were the user-friendliness of the POCT analysers, in addition to other characteristics of the analysers. Results: The following six POCT analysers were evaluated: Uryxxon Relax (Macherey Nagel), Urisys 1100 (Roche), Clinitek Status (Siemens), Aution 11 (Menarini), Aution Micro (Menarini) and Urilyzer (Analyticon). Analytical performance was good for all analysers. Compared with laboratory reference standards, overall agreement was good, but differed per parameter and per analyser. Concerning the nitrite test, the most important test for clinical practice, all but one showed perfect agreement with the laboratory standard. For leucocytes and erythrocytes specificity was high, but sensitivity was considerably lower. Agreement for leucocytes varied between good to very good, and for the erythrocyte test between fair and good. First-time users indicated that the analysers were easy to use. They expected higher productivity and accuracy when using these analysers in daily practice. Conclusions: The overall performance and user-friendliness of all six commercially available POCT urine analysers was sufficient to justify routine use in suspected urinary tract infections in general practice.
Data from: The role of plasma and urine metabolomics in identifying new biomarkers in severe newborn asphyxia: a study of asphyxiated newborn pigs following cardiopulmonary resuscitation
Background: Optimizing resuscitation is important to prevent morbidity and mortality from perinatal asphyxia. The metabolism of cells and tissues is severely disturbed during asphyxia and resuscitation, and metabolomic analyses provide a snapshot of many small molecular weight metabolites in body fluids or tissues. In this study metabolomics profiles were studied in newborn pigs that were asphyxiated and resuscitated using different protocols to identify biomarkers for subject characterization, intervention effects and possibly prognosis. Methods: A total of 125 newborn Noroc pigs were anesthetized, mechanically ventilated and inflicted progressive asphyxia until asystole. Pigs were randomized to resuscitation with a FiO2 0.21 or 1.0, different duration of ventilation before initiation of chest compressions (CC), and different CC to ventilation ratios. Plasma and urine samples were obtained at baseline, and 2 h and 4 h after return of spontaneous circulation (ROSC, heart rate > = 100 bpm). Metabolomics profiles of the samples were analyzed by nuclear magnetic resonance spectroscopy. Results: Plasma and urine showed severe metabolic alterations consistent with hypoxia and acidosis 2 h and 4 h after ROSC. Baseline plasma hypoxanthine and lipoprotein concentrations were inversely correlated to the duration of hypoxia sustained before asystole occurred, but there was no evidence for a differential metabolic response to the different resuscitation protocols or in terms of survival. Conclusions: Metabolic profiles of asphyxiated newborn pigs showed severe metabolic alterations. Consistent with previously published reports, we found no evidence of differences between established and alternative resuscitation protocols. Lactate and pyruvate may have a prognostic value, but have to be independently confirmed.
Simultaneous Determination of Glucose and Albumin in Human Urine for Diagnosing Albuminuria using Attenuated Total Reflection Fourier-Transform Infrared Spectroscopy
<p>The manuscript has not yet been published.</p> <p> </p>
FDG Uptake in Vaginal Tampons is Due to Urine
ClinicalTrials.gov study NCT01215318. IPD Sharing: NO. Countries: 1. Publications: 0.
Using Urine Samples to Identify Lung Cancer
ClinicalTrials.gov study NCT06033248. IPD Sharing: YES. Countries: 1. Publications: 0.
Urine Extracellular Vesicles: Non-invasive Biomarkers of Β-cell Function and Novel Therapeutic Agents in Diabetes
ClinicalTrials.gov study NCT06832215. IPD Sharing: NO. Countries: 1. Publications: 0.
Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury
ClinicalTrials.gov study NCT01531985. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Value of Urine sTREM-1 on Early Predicting AKI in Sepsis
ClinicalTrials.gov study NCT02920736. IPD Sharing: NO. Countries: 0. Publications: 2.
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.