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2,248
datasets available to search
ShareScore release 0.9.0
Dataset results
2,248 results for “squamous cell carcinoma”
Cutaneous squamous cell carcinoma A431 cells treated with itraconazole
GEO Series GSE191037. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
The expression profile of Cetuximab resistance in head-and-neck squamous cell carcinoma cells.
GEO Series GSE63916. Homo sapiens. 2 samples. Type: Expression profiling by array.
Genes expression of cervical squamous cell carcinoma, CaSki cells, treated with or without recombinant TGF-b1 (2 ng/mL)
GEO Series GSE57441. Homo sapiens. 6 samples. Type: Expression profiling by array.
Gene expression profiling to identify potential therapeutic targets and improve prognostication of advanced penile squamous cell carcinoma
GEO Series GSE85730. Homo sapiens. 33 samples. Type: Expression profiling by array.
Mucositis in patients with tonsil squamous cell carcinoma: gene expression profile of oral mucosa before, during, and after radiation therapy
GEO Series GSE103412. Homo sapiens. 64 samples. Type: Expression profiling by array.
The dysregulated inclusion of BOLA3 exon 3 promoted by HNRNPC accelerates the progression of esophageal squamous cell carcinoma in esophageal squamous cell carcinoma
GEO Series GSE235538. Homo sapiens. 38 samples. Type: Expression profiling by high throughput sequencing.
Targeted sequencing of cutaneous squamous cell carcinoma [SCC_NodalMet]
GEO Series GSE196601. Homo sapiens. 10 samples. Type: Genome variation profiling by high throughput sequencing.
Spatial Transcriptomics Reveals Spatially Diverse Cancer-Associated Fibroblast in Lung Squamous Cell Carcinoma Linked to Tumor Progression
<p><span><span>While cancer-associated fibroblasts (CAFs) are crucial in influencing tumor growth and immune responses in lung cancer, we still lack a comprehensive understanding of their spatial organization associated with tumor progression and clinical outcomes. This gap highlights the need to elucidate how the intricate spatial arrangement of CAFs affects their interactions within the tumor microenvironment, ultimately shaping cancer progression and patient prognosis. Here, we unveil the spatial diversity of CAFs in lung squamous cell carcinoma (LUSC), a prevalent and aggressive lung cancer type, elucidating their impact on tumor progression and patient outcomes using spatial transcriptomics (ST). Image-based ST data from 33 LUSC patients demonstrated a significant association of spatial interactions of tumor epithelium and CAFs with tumor size and metabolic activity measured by [<sup>18</sup>F]fluorodeoxyglucose PET. Furthermore, the proximity of fibroblasts to tumor epithelial cells was linked to recurrence-free survival in LUSC patients. By characterizing CAFs based on their spatial relationship, we identified distinct molecular signatures related to spatially distinct fibroblast subpopulations. In addition, barcode-based ST data from 8 LUSC patients revealed spatially overlapping fibroblast regions characterized by upregulated glycolysis pathways. </span></span><span><span><span><span>Our study underscores the importance of the complex spatial dynamics of the tumor microenvironment revealed by ST and its implications for patient outcomes in LUSC.</span></span></span></span></p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.