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290
datasets available to search
ShareScore release 0.9.0
Dataset results
290 results for “Mouse cortex”
RNA-seq data of mouse cerebral cortex in control and UTX conditional knockout groups
GEO Series GSE110392. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Genome-wide maps of Rai1 binding sites in mouse cortex
GEO Series GSE81204. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Wild type vs. Nova2 KO mouse P10 cortex RNA
GEO Series GSE12965. Mus musculus. 14 samples. Type: Expression profiling by array; Genome binding/occupancy profiling by array.
Df(h15q13)/+ mouse model reveals loss of astrocytes and synaptic-related changes of the excitatory and inhibitory circuits in the medial prefrontal cortex.
GEO Series GSE147233. Mus musculus. 15 samples. Type: Expression profiling by high throughput sequencing.
Analysis of the Cerebral Cortex and Hippocampus Transcriptome Reveals Unique Molecular Changes in the Ts1Cje Mouse Model of Down Syndrome
GEO Series GSE49635. Mus musculus. 22 samples. Type: Expression profiling by array.
A transcriptomic atlas of mouse cerebellar cortex reveals novel cell types
GEO Series GSE165371. Homo sapiens; Mus musculus. 141 samples. Type: Expression profiling by high throughput sequencing.
Expression data from P4H-TM knockout mouse cortexes
GEO Series GSE126425. Mus musculus. 2 samples. Type: Expression profiling by array.
Transcriptome profiling in knock-in mouse models of Huntington's disease [Cortex_miRNA]
GEO Series GSE78791. Mus musculus. 96 samples. Type: Expression profiling by high throughput sequencing.
Expression (Gene) in the endothelial cells of the mouse male prefrontal cortex (PFC) following 10-day chronic social stress exposure [male CSDS]
GEO Series GSE182671. Mus musculus. 21 samples. Type: Expression profiling by array.
Promoter-wide profiling of DNA methylation in prefrontal cortex of Camk2-mutPolg mouse.
GEO Series GSE171120. Mus musculus. 26 samples. Type: Methylation profiling by array.
Expression data from adult mouse cortex harvested at two different zeitgeber (ZT) timepoints of the 24h cycle
GEO Series GSE59941. Mus musculus. 8 samples. Type: Expression profiling by array.
Transcriptome-wide maps of m6A methylation in mouse embryonic and postnatal cerebral cortex
GEO Series GSE141938. Mus musculus. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Nova HITS-CLIP and RNA-Seq in mouse cortex
GEO Series GSE69711. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Other.
Wild type vs. Ptbp2 KO mouse embryonic cortex RNA
GEO Series GSE47566. Mus musculus. 6 samples. Type: Expression profiling by array.
Ribosome profiling Seq of mouse adult cortex after acute stress
GEO Series GSE113789. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing; Other.
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Cerebral Cortex
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects transcription spatially in the brain, a greater understanding of this process has the potential to aid strategies that mitigate the effects of spaceflight on the brain. Therefore, we performed GeoMx Digital Spatial Profiling of mouse brains subjected to either spaceflight or grounded controls. Four brain regions were selected: Cortex, Frontal Cortex, Corunu Ammonis I, and Dentate Gyrus. Antioxidants have emerged as a potential means of attenuating the effects of spaceflight, so we treated a subset of the mice with a superoxide dismutase mimic, MnTnBuOE-2-PyP 5+ (BuOE). Our analysis revealed hundreds of differentially expressed genes due to spaceflight in each of the four brain regions. Both common and region-specific transcriptomic responses were observed. Metabolic pathways and pathways sensitive to oxidative stress were enriched in the four brain regions due to spaceflight. These findings enhance our understanding of brain regional variation in susceptibility to spaceflight conditions. BuOE reduced the transcriptomic effects of spaceflight at a large number of genes, suggesting that this compound may attenuate oxidative stress-induced brain damage caused by the spaceflight environment. This study contains data of cerebral cortex region. The data of other brain regions are deposited in OSD-682 (cornu ammonis 1), OSD-685 (dentate gyrus), and OSD-698 (frontal cortex).
Spaceflight-Induced Gene Expression Profiles in the Mouse Brain Are Attenuated by Treatment with the Antioxidant BuOE - Frontal Cortex
The demands of deep space pose a health risk to the central nervous system that has long been a concern when sending humans to space. While little is known about how spaceflight affects transcription spatially in the brain, a greater understanding of this process has the potential to aid strategies that mitigate the effects of spaceflight on the brain. Therefore, we performed GeoMx Digital Spatial Profiling of mouse brains subjected to either spaceflight or grounded controls. Four brain regions were selected: Cortex, Frontal Cortex, Corunu Ammonis I, and Dentate Gyrus. Antioxidants have emerged as a potential means of attenuating the effects of spaceflight, so we treated a subset of the mice with a superoxide dismutase mimic, MnTnBuOE-2-PyP 5+ (BuOE). Our analysis revealed hundreds of differentially expressed genes due to spaceflight in each of the four brain regions. Both common and region-specific transcriptomic responses were observed. Metabolic pathways and pathways sensitive to oxidative stress were enriched in the four brain regions due to spaceflight. These findings enhance our understanding of brain regional variation in susceptibility to spaceflight conditions. BuOE reduced the transcriptomic effects of spaceflight at a large number of genes, suggesting that this compound may attenuate oxidative stress-induced brain damage caused by the spaceflight environment. This study contains data of frontal cortex region. The data of other brain regions are deposited in OSD-682 (cornu ammonis 1), OSD-685 (dentate gyrus), and OSD-699 (cerebral cortex).
Gene expression in the mouse cerebral cortex exposed to Bisphenol A (BPA) during development.
GEO Series GSE53158. Mus musculus. 12 samples. Type: Expression profiling by array.
Ribosome profiling and RNA-seq of Fragile X mouse brain cortex
GEO Series GSE140565. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing; Other.
RNA-Seq analysis of E4FAD mouse brain cortex to evaluate the impact of omega-6 fatty acid docosapentaenoic acid on neuroinflammation
GEO Series GSE156936. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.