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3,748 results for “Pregnancy”
Data from: The embryonic DPPA3 gene stimulates the expression of pregnancy-related genes in bovine endometrial cells
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SAFER: Safer conception strategies to prevent HIV transmission among HIV sero-different couples desiring pregnancy
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Pregnancy outcomes in facility deliveries in Kenya and Uganda: A large cross-sectional analysis of maternity registers illuminating opportunities for mortality prevention
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Association between seven-day serum β-hCG levels after frozen–thawed embryo transfer and pregnancy outcomes: a single-centre retrospective study from China
<p><span><b><span>Objective:</span></b> Early monitoring of plasma human chorionic gonadotropin (β-hCG) level is vital in predicting pregnancy outcome. This study investigated the predictive value of serum β-hCG level on the 7th day after frozen-thawed embryo transfer (FET) for ongoing pregnancy (OP) and adverse pregnancy (AP). </span></p> <p><span><b><span>Design: </span></b>Retrospective study</span></p> <p><span><b><span>Setting:</span></b> The Reproductive and Genetic Center of the Affiliated Hospital of Shandong University of Traditional Chinese Medicine, China.</span></p> <p><span><b><span>Participants: </span></b>1,061 pregnant women who underwent FET between January 2014 and January 2017. </span></p> <p><span><b><span>Primary and secondary outcome measures: </span></b>Pregnancy outcome.</span></p> <p><span><b><span>Results: </span></b>Serum β-hCG levels on the 7th day after FET were higher in the single OP group compared to the biochemical pregnancy (BP) group (p <0.001). Besides, the serum β-hCG cutoff level at 4.34 mIU/mL on the 7th day showed high predictive value (area under the curve [AUC] = 0.852). Serum β-hCG levels on the 7th day after FET were higher in the twin OP group compared to the single OP group (p<0.001). Also, the serum β-hCG cutoff level at 17.95 mIU/mL on the 7th day showed high predictive value (AUC = 0.903). Serum β-hCG levels on the 7th day after FET were lower in the ectopic pregnancy (EP) group compared to the single OP group (p <0.001) whereas, serum β-hCG cutoff level at 4.53 mIU/mL on the 7th day exhibited a high predictive value (AUC = 0.860). Further, the serum β-hCG levels on the 7th day after FET were lower in the single early spontaneous abortion (SA) group compared to the single OP group (p<0.001) while the serum β-hCG cutoff level at 5.34 mIU/mL on the 7th day exhibited high predictive value (AUC = 0.738).</span></p> <p><span><b><span>Conclusion:</span></b> Serum β-hCG on the 7th day after FET has good clinical significance for the prediction of OP and AP.</span></p>
Parenting costs time: Changes in pair bond maintenance across pregnancy and infant rearing in a monogamous primate (Plecturocebus cupreus) [dataset]
<p>Relationships support social animals’ health, but maintaining relationships is challenging. When transitioning to parenthood, new parents balance pair-bond maintenance with infant care. We studied pair-bond maintenance via affiliation in 22 adult titi monkey pairs (<em>Plecturocebus cupreus</em>) for 16 months centered around their first offspring’s birth. Pair affiliation peaked during pregnancy, decreased across the postpartum period, and rose after reaching minimum affiliation 32.6 weeks postpartum. Pairs in which fathers infant-carry more than average had lower affiliation at the infant’s birth and return to an increase in affiliation sooner. Parents of infants who were slow to independence had higher rates of affiliation. Titi monkey infants actively prefer their fathers; mothers may avoid their infant-carrying mate, suggesting infants play an active role in parental affiliative decline. Our data supports previous findings that affiliation between partners declines following an infant’s birth, but demonstrates new knowledge about the extent and duration of affiliative decline.</p>
Data from: Aspirin reduces long term stroke risk in women with prior hypertensive disorders of pregnancy
OBJECTIVE: To determine if hypertensive disorders of pregnancy (HDP) increased long-term stroke risk in women in the California Teachers Study (CTS), a prospective cohort study, and if aspirin or statin use modified this risk. METHODS: CTS participants aged ≤60 years at time of enrollment in 1995 were followed prospectively for validated stroke outcomes obtained via linkage with California hospital records through 12/31/2015. We calculated unadjusted and adjusted hazard ratios (HR) and 95% confidence intervals (95%CI) for the primary outcomes of (1) all stroke and (2) stroke before age 60, among those with and without history of HDP. We tested for interactions (p<0.2) and performed stratified analyses to assess risk of the primary outcomes in women with and without self-reported use of aspirin or statins. RESULTS: Of 83,749 women included in the analysis, 4070 (4.9%) had HDP. Women with prior HDP had increased risk of all stroke (adjusted HR 1.3, 95%CI 1.2-1.4) but no increased risk of stroke before age 60 (adjusted HR 1.2, 95%CI 0.9-1.7). There was an interaction (p=0.18) between aspirin use and HDP history on risk of stroke before age 60: non-aspirin users had higher risk (adjusted HR 1.5, 95%CI 1.0-2.1) while aspirin users did not (adjusted HR 0.8, 95%CI 0.4-1.7). This effect was not seen with statins. CONCLUSIONS: Controlling for comorbidities, women with prior HDP had increased long-term stroke risk, which was reduced by aspirin use. Randomized trials may be needed to assess whether long-term aspirin use could benefit selected women with a history of HDP.
Data from: Cost effectiveness of the New Zealand diabetes in pregnancy guideline screening recommendations
Objective: To compare the cost-effectiveness of 2 possible screening strategies for gestational diabetes mellitus (GDM) from the perspective of the New Zealand health system, developed as part of a gestational diabetes guideline. Design: A decision analytic model was built comparing 2-step screening (glycated haemoglobin (HbA1c) test at first booking and a 2 h 75 g oral glucose tolerance test (OGTT) as a single test at 24–28 weeks) with 3-step screening (HbA1c test at first booking and a 1 h glucose challenge test (GCT) followed by a 2 h 75 g OGTT when indicated from 24–28 weeks) using a 9-month time horizon. Setting: A hypothetical cohort of 62 000 pregnant women in New Zealand. Methods: Probabilities, costs and benefits were derived from the literature, and supplementary data was obtained from National Women's Annual Clinical Reports. Main outcome measures, screening and treatment costs (NZ$2013) and effect on health outcomes (incidence of complications). Results: The total cost for both strategies under baseline assumptions shows that the 2-step screening strategy would cost NZ$1.38 m more than the 3-step screening strategy overall. The additional cost per case detected was NZ$12 460 per case. The model found that the 2-step screening strategy identifies 12 more women with diabetes and 111 more women with GDM when compared against the 3-step screening strategy. We assessed the effect of changing the sensitivity and specificity of the OGTT. The baseline model assumed that the 2 h 75 g OGTT has a sensitivity and specificity of 95%. The 2-step strategy becomes more cost-effective when the diagnostic accuracy measures are improved. Conclusions: Adopting a 2-step strategy would moderately increase the number of GDM cases detected at the same time as moderately increasing the number of women with false negatives at a significant cost to the health system. Further evidence on the benefits of the 2 different approaches would be welcome.
Data from: Impact of caesarean section on mode of delivery, pregnancy-induced and pregnancy-associated disorders, and complications in the subsequent pregnancy in Germany
Objectives: To analyze the impact of caesarean section (CS) on mode of delivery, pregnancy-induced and pregnancy-associated disorders, as well as complications in the subsequent pregnancy within German gynecological practices. Methods: 1,801 women with CS and 1,801 matched women with vaginal delivery (VD) from the IMS Disease Analyzer database were included. The impact of previous CS on the mode of delivery and pregnancy-associated disorders as well as complications prior to or during birth in the subsequent pregnancy were analyzed. Cox regressions were used to determine the influence of CS with regard to these outcomes. Results: Medical abortion and single spontaneous delivery were significantly less frequent in women with a history of CS compared to VD (OR equal to 0.52 and 0.04 respectively), whereas CS after CS was the significantly more common mode of delivery (79.0% versus 9.3%, OR=36.47). Gestational hypertension without significant proteinuria, gestational hypertension with significant proteinuria, and polyhydramnios were more frequent in women with CS than in women with VD (OR equal to 6.80, 1.71, and 2.29). Hemorrhage and maternal care for known or suspected disproportion were more common in the CS group than in the VD group (OR equal to 1.34 and 3.75). Prolonged pregnancy, preterm labor, abnormalities arising from forces of labor, and perineal laceration during delivery were significantly less frequent in women with CS than in women with VD (OR between 0.32 and 0.75), whereas long labor was more common (OR=2.09). Conclusion: Women with CS were more likely to undergo further CS and to develop major pregnancy-associated diseases in the following pregnancy compared to women with VD.
Data from: The "Woman in Red" Effect: pipefish males curb pregnancies at the sight of an attractive female
In an old Gene Wilder movie, an attractive woman dressed in red devastated a man's current relationship. We have found a similar "Woman in Red" effect in pipefish, a group of fish where pregnancy occurs in males. We tested for the existence of pregnancy blocks in pregnant male black-striped pipefish (Syngnathus abaster). We allowed pregnant males to see females that were larger and even more attractive than their original high-quality mates and monitored the survival and growth of developing offspring. After exposure to these extremely attractive females, males produced smaller offspring in more heterogeneous broods and showed a higher rate of spontaneous offspring abortion. Although we did not observe a full pregnancy block, our results show that males are able to reduce investment in current broods when faced with prospects of a more successful future reproduction with a potentially better mate. This "Woman in Red" life history trade-off between present and future reproduction has similarities to the Bruce effect, and our study represents the first documentation of such a phenomenon outside mammals.
Data from: Primary care follow-up and measured mental health outcomes among women referred for ultrasound assessment of pain and/or bleeding in early pregnancy: a quantitative questionnaire study
Objectives To examine the extent of primary care follow-up and mental health outcomes among women referred for ultrasound assessment of pain and/or bleeding in early pregnancy, including those whose pregnancy is found to be viable on ultrasound assessment. Design Questionnaire study with prospective follow-up. Setting Urgent gynaecology clinic in secondary care, England. Participants 57 women participated in the study. Entry criteria: referral to the urgent gynaecology clinic with pain and/or bleeding in early pregnancy; gestation less than 16 weeks (the clinic's own 'cut-off'); no previous attendance at the clinic during the current pregnancy. Exclusion criteria: inability to understand English or to provide informed consent. Primary and secondary outcome measures Incidence of primary care follow-up among women referred to the urgent gynaecology clinic; incidence of women with measured mental health scores suggesting significant symptoms of distress. Results Fewer than 1 in 10 women referred for ultrasound assessment of pain and/or bleeding in early pregnancy had follow-up arrangements made with their general practitioner (GP). Most women who had GP follow-up found it helpful and a significant minority of women who did not have GP follow-up felt that it would have been helpful. Following ultrasound assessment, more than one-third of women had significant symptoms of distress. Symptoms of distress, particularly anxiety, were present among those women found to have viable pregnancies, as well as among those with non-viable pregnancies. Conclusions GPs are advised to consider offering follow-up to all women referred for ultrasound assessment of pain and/or bleeding in early pregnancy. Researchers in this area are advised to consider the experiences of women with pain and/or bleeding in early pregnancy whose pregnancies are ultimately found to be viable on ultrasound scan.
Data from: Ambulatory versus inpatient management of severe nausea and vomiting of pregnancy: a randomized control trial with patient preference arm
ABSTRACT Objective To determine whether ambulatory (outpatient, OP) treatment of severe nausea and vomiting of pregnancy (NVP) is as effective as inpatient (IP) care. Design Non-blinded randomized control trial (RCT) with patient preference arm Setting Multi-center Participants Women less than 20 weeks pregnant with severe NVP and associated ketonuria Methods Women participating in the RCT were randomized via web-based application to either ambulatory or IP treatment. Women declining randomisation entered the patient preference trial (PPT) arm. Protocols, data collection and follow-up were the same for all participants. Main Outcome Measures Primary outcome was reduction in Pregnancy Unique Quantification of Emesis (PUQE) score at 48 hours. Secondary outcomes were duration of treatment; improvement in symptom scores and ketonuria at 48 hours; re-attendances within 7 days of discharge; and comparison of symptoms at 7 days post discharge Results 152/174 eligible women agreed to participate with 77/152 (51%) recruited to the RCT and 79/152 (49%) to the PPT. Patients were initially compared in 4 groups (randomized IP, randomized OP, non-randomized IP and non-randomized OP). Comprehensive cohort analysis of participants in the (RCT) and (PPT) did not demonstrate any differences in patient demographics or baseline clinical characteristics. Pooled analysis of IP versus OP groups showed no difference in reduction in PUQE score at 48 hours (p=0.86). There was no difference in change in eating score (p=0.69), drinking score (p=0.77), wellbeing rating (p=0.64) or reduction in ketonuria (p=0.47) at 48 hours, with no difference in duration of index treatment episode (p=0.83) or re-attendances within 7 days (p=0.52). Conclusions Ambulatory management is an effective alternative to inpatient management of severe NVP. The trial also demonstrated that many women requiring treatment for HG have a strong preferences regarding treatment setting, which needs to be considered by care providers, especially given the psychological impact of HG.
Data from: Maternal pre-pregnancy weight status modifies the influence of PUFAs and inflammatory biomarkers in breastmilk on infant growth
Background: Human breastmilk contains pro- and anti-inflammatory compounds and hormones that can influence infant growth. However, little is known about the specific interrelationships between these compounds and whether their effects on infant growth may be influenced by pre-pregnancy weight status. Objective: The purpose of this novel, prospective cohort study was to assess the interrelationships between pro-inflammatory cytokines (TNF-α, IL-6), hormones (insulin, leptin) and PUFAs (n-6, n-3) in blood and breastmilk in early postpartum between women with normal BMI (Group 1, n=18; 18.5
Data from: Water availability and temperature induce changes in oxidative status during pregnancy in a viviparous lizard
<ol> <li>Reproduction involves considerable reorganization in an organism's physiology that incurs potential toxicity for cells (e.g., oxidative stress) and decrease in fitness. This framework has been the cornerstone of the so-called 'oxidative cost of reproduction', a theory that remains controversial and relatively overlooked in non-model ectotherms.</li> <li>Here, we used two complementary approaches in natural and controlled conditions to test whether altered access to climate conditions (water and temperature resources) alters oxidative status and mediates reproductive trade-offs in viviparous populations of the common lizard (<i>Zootoca vivipara</i>).</li> <li>First, we examined whether access to free standing water and differences in ambient temperature across 12 natural populations could be related with variation in oxidative status, reproductive effort and reproductive success. Second, we determined whether an experimental restriction to water triggers higher oxidative cost of reproduction and correlates with fitness measures (reproductive success, future survival rate and probability of future reproduction).</li> <li>Pregnant females exhibited higher sensitivity than males to natural or experimental limitations in temperature and water access. That is, in restricted environments, pregnant females with higher reproductive effort exhibited stronger oxidative damage despite enhanced non-enzymatic antioxidant capacity.</li> <li>Enhanced antioxidant defensive capacity in pregnant females was positively correlated with higher reproductive success, whereas elevated oxidative damage negatively correlated with offspring annual survival. </li> <li>Altogether, our results revealed a context-dependent oxidative cost of reproduction that was concomitant with a conflict in water demand from offspring. These new insights should be critical for understanding ectotherm responses to heat waves and summer droughts that are increasing in frequency and duration.</li> </ol>
Global Transcriptomic Analysis of Placenta from Women with Gestational SARS-CoV-2 Infection during the 3rd Trimester of Pregnancy
<p>Supplementary data for <strong>Global Transcriptomic Analysis of Placenta from Women with Gestational SARS-CoV-2 Infection during the 3rd Trimester </strong><br><strong>of Pregnancy</strong></p>
Vitamin D Deficiency and Pregnancy Outcome: A longitudinal Interventional Study
<p><strong><u><span>ABSTRACT</span></u></strong><span>:</span></p> <p><strong><span>Introduction:</span></strong><span> <span>Vitamin D is a fat-soluble vitamin responsible for increasing the absorption of calcium, magnesium, phosphate, and multiple other biological effects. Deficiency of vitamin D is a common global problem, especially in females. It is naturally produced by the body on exposure to sunlight. Deficiency of vitamin D in pregnancy predisposes to pre-eclampsia, GDM, preterm birth to the mother, hypocalcemic tetany, low birth weight, and congenital rickets in the fetus. In general, 10 (400) units of vitamin D are recommended for all pregnant women per day.</span></span><span> <strong><span>Materials and methods:</span></strong> The study was conducted in the OBGY department of MGM Medical College, Aurangabad, Maharashtra, between August 2022 to August 2023. A complete procedure was explained to all the second-trimester pregnant women willing to participate in this study, and informed written consent was obtained from them. Their detailed history was taken and subjected to an estimation of 25 hydroxyvitamin D and serum calcium. <strong><span>Results:</span></strong> A high prevalence of vitamin D deficiency is found (81%). In teenage pregnancy, the occurrence of vitamin D deficiency is higher. In our study, vitamin D deficiency was more prevalent in rural areas thanurban areas. It was more in the Muslim population. A sedentary life is prone to vitamin D deficiency. The incidence of GDM, pre-eclampsia, and low birth weight was significantly lower in tested and treated patients. Empirical vitamin D supplementation should be given to each pregnant patient.</span></p> <p><strong><em><span> </span></em></strong></p> <p><strong><em><span>Keywords: GDM, Preeclampsia, prevalence, teenage pregnancy, low birth weight.</span></em></strong></p> <p><span> </span></p>
Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age
<p>Taschereau, A., Thibeault, K., Allard, C., Juvinao-Quintero, D., Perron, P., Lutz, S. M., Bouchard, L., & Hivert, M. F. (2023). Maternal glycemia in pregnancy is longitudinally associated with blood DNAm variation at the FSD1L gene from birth to 5 years of age. Clinical epigenetics, 15(1), 107. https://doi.org/10.1186/s13148-023-01524-7</p> <p>Background<br>In utero exposure to maternal hyperglycemia has been associated with an increased risk for the development of chronic diseases in later life. These predispositions may be programmed by fetal DNA methylation (DNAm) changes that persist postnatally. However, although some studies have associated fetal exposure to gestational hyperglycemia with DNAm variations at birth, and metabolic phenotypes in childhood, no study has yet examined how maternal hyperglycemia during pregnancy may be associated with offspring DNAm from birth to five years of age.</p> <p>Hypothesis<br>Maternal hyperglycemia is associated with variation in offspring DNAm from birth to 5 years of age.</p> <p>Methods<br>We estimated maternal hyperglycemia using the area under the curve for glucose (AUCglu) following an oral glucose tolerance test conducted at 24–30 weeks of pregnancy. We quantified DNAm levels in cord blood (n = 440) and peripheral blood at five years of age (n = 293) using the Infinium MethylationEPIC BeadChip (Illumina). Our total sample included 539 unique dyads (mother–child) with 194 dyads having DNAm at both time-points. We first regressed DNAm M-values against the cell types and child age for each time-point separately to account for the difference by time of measurement for these variables. We then used a random intercept model from the linear mixed model (LMM) framework to assess the longitudinal association between maternal AUCglu and the repeated measures of residuals of DNAm. We adjusted for the following covariates as fixed effects in the random intercept model: maternal age, gravidity, smoking status, child sex, maternal body mass index (BMI) (measured at first trimester of pregnancy), and a binary variable for time-point.</p> <p>Results<br>In utero exposure to higher maternal AUCglu was associated with lower offspring blood DNAm levels at cg00967989 located in FSD1L gene (β = − 0.0267, P = 2.13 × 10–8) in adjusted linear regression mixed models. Our study also reports other CpG sites for which DNAm levels were suggestively associated (P < 1.0 × 10–5) with in utero exposure to gestational hyperglycemia. Two of these (cg12140144 and cg07946633) were found in the promotor region of PRDM16 gene (β: − 0.0251, P = 4.37 × 10–07 and β: − 0.0206, P = 2.24 × 10–06, respectively).</p> <p>Conclusion<br>Maternal hyperglycemia is associated with offspring DNAm longitudinally assessed from birth to 5 years of age.</p> <p> </p> <p> </p>
Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence
<p>Choudhary, P., Monasso, G. S., Karhunen, V., Ronkainen, J., Mancano, G., Howe, C. G., Niu, Z., Zeng, X., Guan, W., Dou, J., Feinberg, J. I., Mordaunt, C., Pesce, G., Baïz, N., Alfano, R., Martens, D. S., Wang, C., Isaevska, E., Keikkala, E., Mustaniemi, S., … Sebert, S. (2023). <a href="https://pubmed.ncbi.nlm.nih.gov/38052982/">Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence.</a> Molecular psychiatry, 10.1038/s41380-023-02331-5. Advance online publication. https://doi.org/10.1038/s41380-023-02331-5</p> <p>Maternal educational attainment (MEA) shapes offspring health through multiple potential pathways. Differential DNA methylation may provide a mechanistic understanding of these long-term associations. We aimed to quantify the associations of MEA with offspring DNA methylation levels at birth, in childhood and in adolescence. Using 37 studies from high-income countries, we performed meta-analysis of epigenome-wide association studies (EWAS) to quantify the associations of completed years of MEA at the time of pregnancy with offspring DNA methylation levels at birth (n = 9 881), in childhood (n = 2 017), and adolescence (n = 2 740), adjusting for relevant covariates. MEA was found to be associated with DNA methylation at 473 cytosine-phosphate-guanine sites at birth, one in childhood, and four in adolescence. We observed enrichment for findings from previous EWAS on maternal folate, vitamin-B12 concentrations, maternal smoking, and pre-pregnancy BMI. The associations were directionally consistent with MEA being inversely associated with behaviours including smoking and BMI. Our findings form a bridge between socio-economic factors and biology and highlight potential pathways underlying effects of maternal education. The results broaden our understanding of bio-social associations linked to differential DNA methylation in multiple early stages of life. The data generated also offers an important resource to help a more precise understanding of the social determinants of health.</p>
A Survey of Emotional and Mental Health Effects Women Attribute to Their Pregnancy Outcomes
<h2>Materials and Methods</h2> <p><span>Experts in abortion and mental health research were consulted in preparing a questionnaire into the prevalence and effects of abortions that conflict with women’s own maternal preferences and moral beliefs. </span></p> <h3>Study Population</h3> <p><span>Invitations to complete a topic blind survey were electronically distributed to Cint.com panelists over a three-day period in July of 2024. Cint panelists are persons who voluntarily complete surveys using their own electronic devices in exchange for small rewards with a value, for this invitation, of under $2 per completed survey. The Cint survey panels include over 28 million U.S. residents. For this survey, a random sample of United States residents Cint pre-identified as females 41 to 45 years of age were invited to complete a survey housed on the LimeSurvey.org platform without any disclosure of the subject matter. The narrow age range, 41-45 years of age, was chosen to (a) eliminate the confounding effects of age, and (b) to maximize the proportion of respondents with a history of abortion since this age group will have completed the majority of their reproductive lives. Investigation of younger women has been deferred until we can test the survey instrument with this limited age group. </span></p> <p><span>The survey exposure rate, response rates, and exclusion rates are shown in Figure 1. Respondents who did not complete all questions were excluded from the analysis, as were any respondents who were out of our gender and age range. Among the 2,361 people who completed the first page of demographic questions, 123 (5.2%) dropped by failing to complete the psychiatric history and another 25 (1.1%) dropped out when presented with questions relating to abortion. Another 22 (1.0%) dropped out when asked their own pregnancy outcomes histories and 166 (7.0%) dropped out, after reporting their pregnancy histories, before completing the survey. The survey was designed to be completed in approximately five to seven minutes by respondents reporting any pregnancies. Of those who completed the survey, 100 (4.6%) were excluded for completing the survey in an unreasonably short period of time, under four minutes. The exclusion of these “speedsters” reflected the likelihood that some respondents, seeking to earn credit for completing the survey as quickly as possible, were randomly responding without reading or considering the questions.</span></p> <p> </p> <p><span></span></p> <p><span> </span></p> <p><span>Figure </span><span><span>1</span></span><span>: Study Population</span></p> <h3>Variables used</h3> <p><span>The first page of the questionnaire asked about age and gender to qualify respondents. The second page included a list of eleven mental health diagnoses and asked respondents to identify which, if any, they had ever been diagnosed. </span></p> <p><span>Only after this page were respondents asked if they had ever had an “unplanned, mistimed, unwanted, or otherwise difficult pregnancy,” which was defined and thereafter referred to as a “problematic pregnancy.” They were then asked to identify the number of times they had “given birth to a live born child,” “had a miscarriage, still birth or other pregnancy loss” and “had an induced abortion.” From this pregnancy history women were divided by a program algorithm into one of five groups, by order of priority: those who had a history of induced abortions, had experienced natural pregnancy losses, had problematic pregnancies carried to term, or had live births, or had never been pregnant. Results from this grouping is shown in Table 1. Notably, given the algorithm prioritization, women in the abortion group may also have had one or more live births, natural pregnancy losses, and problematic pregnancies ending in a live birth. But women were included in the live birth group only if they had none of the other pregnancy outcomes. </span></p> <p><span>The rest of the variables are described in the repository document "2nd USA Survey Instrument.pdf" and in the limesurvey code, "2nd USA survey limesurvey.lss."</span></p>
Differential Proteomics of Placentas Revels Metabolic Disturbance and Oxidative Stress Participate Spontaneous Abortion during Late Pregnancy in Yak
<p>Supplementary tables used for a article titled "Differential Proteomics of Placentas Revels Metabolic Disturbance and Oxidative Stress Participate Spontaneous Abortion during Late Pregnancy in Yak"</p>
16S rDNA sequence data of research--Different periods of high-fat diet during peri-pregnancy cause variant offspring gut microbiota
<p> These are the 16S rRNA gene sequencing data based on the Illumina HiSeq2500 platform. Group a, b, c, d stand for group CD-CD, CD-HFD, HFD-CD, HFD-HFD separately. Each mouse of one group had two samples such as a1_1 and a1_2.</p>
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
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