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225 results for “congestive heart failure”
Effects on expression profile of acute congestive heart failure (ACHF) patients monocytes by treatment with conventional drugs.
GEO Series GSE51888. Homo sapiens. 11 samples. Type: Expression profiling by array.
Control and Congestive Heart Failure
GEO Series GSE632. Rattus norvegicus. 6 samples. Type: Expression profiling by array.
Dataset related to article: "Diffuse idiopathic skeletal hyperostosis in subjects with congestive heart failure undergoing cardiac rehabilitation: A decision tree analysis"
<p>We provide the raw data used for the following article:</p> <ul> <li> <p>Ambrosino P, Scrutinio D, De Campi M, Miniero E, Formisano R, Spedicato GA, Iannuzzi GL, Pappone N.<br> <em>Diffuse idiopathic skeletal hyperostosis in subjects with congestive heart failure undergoing cardiac rehabilitation: A decision tree analysis. </em><br> "J Rehabil Med". 2020 Mar 18;52(3):jrm00030. doi: 10.2340/16501977-2658. PMID: 32104899.</p> </li> </ul> <p> </p> <p><strong>Abstract</strong></p> <p><strong>Objective: </strong> To assess the prevalence of diffuse idiopathic skeletal hyperostosis and its relationship with vascular risk factors among patients with congestive heart failure.</p> <p><strong>Design: </strong> Population-based cross-sectional study.</p> <p><strong>Participants: </strong> A total of 584 consecutive patients admitted to a Rehabilitative Cardiology Unit.</p> <p><strong>Methods: </strong> Chi-square Automatic Interaction Detector (CHAID) decision tree analysis was used to build a predictive model.</p> <p><strong>Results: </strong> The mean age (standard deviation) of the study population was 68.1 years (standard deviation 12.3), and 77.7% of the subjects were men. The overall prevalence of diffuse idiopathic skeletal hyperostosis in the cohort was 49.8%. Logistic regression analysis showed that age was a predictor of diffuse idiopathic skeletal hyperostosis (odds ratio: 1.034; 95% confidence interval 1.021-1.047, p < 0.001), with increasing odds ratios for increasing age tertiles. The CHAID prediction model identified 2 age "buckets": < 69 and ≥ 69 years. Patients ≥ 69 years had a diffuse idiopathic skeletal hyperostosis prevalence of 60.1%, compared with 39.2% among those < 69 years. Notably, body mass index was a predictor of diffuse idiopathic skeletal hyperostosis in this younger subset of patients (p = 0.028), with 2 body mass index "buckets", ≤ 23.3 and > 23.3 kg/m2, the latter showing more than twice the prevalence of diffuse idiopathic skeletal hyperostosis (43.2% vs 20%).</p> <p><strong>Conclusion: </strong> Diffuse idiopathic skeletal hyperostosis is extremely frequent among patients with congestive heart failure, with age and body mass index being the strongest predictors.</p>
Dataset from: "Prognostic Value of Dynamic Changes in Pulmonary Congestion During Exercise Stress Echocardiography in Heart Failure With Preserved Ejection Fraction"
<p>BACKGROUND: Patients with heart failure (HF) with preserved ejection fraction (HFpEF) typically develop dyspnea and<br> pulmonary congestion upon exercise. Lung ultrasound is a simple diagnostic tool, providing semiquantitative assessment<br> of extravascular lung water through B-lines. It has been shown that patients with HFpEF develop B-lines upon submaximal<br> exercise stress echocardiography; however, whether exercise-induced pulmonary congestion carries prognostic implications<br> is unknown. This study aimed at evaluating the prognostic value of B-line assessment during exercise in patients with HFpEF.<br> METHODS: Sixty-one New York Heart Association class I to II patients with HFpEF underwent standard echocardiography,<br> lung ultrasound (28-scanning point method), and BNP (B-type natriuretic peptide) assessment during supine exercise<br> echocardiography (baseline and peak exercise). The primary end point was a composite of cardiovascular death or HF<br> hospitalization at 1 year.<br> RESULTS: B-lines, E/e′, and BNP significantly increased during exercise (P<0.001 for all). By multivariable analysis, both peak<br> (hazard ratio, 1.50 [95% CI, 1.21–1.85], P<0.001), and change (hazard ratio 1.34 [95% CI, 1.12–1.62], P=0.002) B-lines<br> were retained as independent predictors of outcome (hazard ratios per 1 B-line increment), along with BNP and E/e′ ratio.<br> Importantly, adding peak B-line on top of a clinical model significantly improved prognostic accuracy (C-index increase, 0.157<br> [0.056–0.258], P=0.002) and net reclassification (continuous net reclassification improvement, 0.51 [0.09–0.74], P=0.016),<br> with similar results for B-line change.<br> CONCLUSIONS: Detection of exercise-induced pulmonary congestion by lung ultrasound is an independent predictor of outcome<br> in patients with HFpEF; its use may help refining the routine risk stratification of these patients on top of well-established<br> clinical variables.</p>
Congestive heart failure in dog
GEO Series GSE472. Homo sapiens; Canis lupus familiaris. 5 samples. Type: Expression profiling by array.
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International Brain Laboratory public data
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OpenNeuro
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