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244
datasets available to search
ShareScore release 0.9.0
Dataset results
244 results for “genomic variants”
Genome-wide profiling of linker histone variant H1.3 in T47D-MTVL cancer cell line
GEO Series GSE236878. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Saturation genome editing of 11 codons and exon 13 of BRCA2 determines pathogenicity of variants
GEO Series GSE238143. Mus musculus. 49 samples. Type: Other.
High-resolution genomic profiling of marginal zone B-cell lymphomas and variants
GEO Series GSE36311. Homo sapiens. 30 samples. Type: Genome variation profiling by SNP array.
Genome-wide maps of chromatin state (heterochromatin H3K9me2 or centromeric histone H3 variant CENP-A/Cnp1) in heterozygous deletion diploid mhf2∆/+ and the meiotic haploid progeny of heterozygous del
GEO Series GSE117954. Schizosaccharomyces pombe. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Beyond chromatin: The role of histone variant H2A.B in modulating the genomic distribution of SWI/SNF in cancer
GEO Series GSE291025. Homo sapiens. 18 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide maps of chromatin state (centromeric histone H3 variant CENP-A/Cnp1) in clr4∆ and the transformants from the deletion of clr4 in mhf2∆ (cen2_inactive) or mhf2+ (cen1_inactive).
GEO Series GSE131226. Schizosaccharomyces pombe. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide occupancy of linker histone variant H1t in pachytene spermatocytes
GEO Series GSE142081. Mus musculus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide maps of chromatin state (heterochromatin H3K9me2 or centromeric histone H3 variant CENP-A/Cnp1) in the meiotic progeny from the crossings of mhf2+ (cen1_inactive) × mhf2+ (cen1_active) and
GEO Series GSE117957. Schizosaccharomyces pombe. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide enhancer-gene regulatory maps link causal variants to target genes underlying human colorectal cancer risk [H3K27ac ChIP-seq]
GEO Series GSE222768. Homo sapiens. 20 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station
Bacillus pumilus SAFR-032, an endospore-forming bacterial strain, was investigated to determine its methylation pattern (methylome) change, compared to ground control, after direct exposure to space conditions onboard the International Space Station (ISS) for 1.5 years. The resulting ISS-flown and non-flown strains were sequenced using the Nanopore MinION and an in-house method and pipeline to identify methylated positions in the genome. Our analysis indicated genomic variants and m6A methylation increased in the ISS-flown SAFR-032. To complement the broader omics investigation and explore phenotypic changes, ISS-flown and non-flown strains were compared in a series of laboratory-based chamber experiments using an X-ray irradiation source (doses applied at 250, 500, 750, 1000 and 1250 Gy); results show a potentially higher survival fraction of ISS-flown DS2 at the two highest exposures. Taken together, results from this study document lasting changes to the genome by methylation, potentially triggered by conditions in spaceflight, with functional consequences for the resistance of bacteria to stressors expected on long-duration missions beyond low Earth orbit.
Comparative genome-scale analysis of Pichia pastoris variants informs selection of an optimal base strain [protein expression]
GEO Series GSE135665. Komagataella phaffii. 72 samples. Type: Expression profiling by high throughput sequencing.
Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM
GEO Series GSE296243. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses
GEO Series GSE154537. Mus musculus. 4 samples. Type: Expression profiling by array.
Saturation genome editing-based functional evaluation and clinical 2 classification of BRCA2 single nucleotide variants
GEO Series GSE270424. Homo sapiens. 144 samples. Type: Other.
Genome-wide occupancy of linker histone variant H1T2 in round/elongating spermatids of rats
GEO Series GSE162144. Rattus norvegicus. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Genome-wide binding of wild-type p53 and R248Q missense mutant variants in isogenic human acute myeloid leukemia (AML) cell lines
GEO Series GSE284299. Homo sapiens. 4 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single-cell genome-wide association reveals a nonsynonymous variant in ERAP1 confers increased susceptibility to influenza virus
GEO Series GSE205796. Homo sapiens. 7 samples. Type: Expression profiling by high throughput sequencing.
Aggregated variant data from whole-genome sequenced tinnitus patients (TIGER)
<p>Aggregated variant data obtained from tinnitus patients from Sweden.</p> <p>Uploaded datasets are storage in annotated csv files. Annotation was performed using VEP (v106), including population frequencies for each variant from gnomAD, non-finnish Europeans from gnomAD, and swedish population from SweGen project. Pathogenicity scores from CADD are also annotated for each variant. Variants from genes found to be enriched in a gene burden analysis can be found in this aggregated dataset.</p> <p><strong>agg.tiger.csv</strong> - TIGER cohort is composed by 97 swedish whole-genome sequenced constant tinnitus patients.</p> <p><strong>agg.jaguar.csv</strong> - JAGUAR cohort is composed by 147 swedish whole-exome sequenced tinnitus patients .</p> <p><strong>agg.sevtin.csv</strong> - SEVTIN cohort is a subcohort from TIGER, with 34 WGS patients seggregating severe tinnitus phenotype.</p> <p><strong>agg.controls.csv</strong> - Controls is a swedish population cohort composed by 151 whole-exome sequenced swedish individuals.</p>
Androgen receptor variant 7 non-canonical genome integrity functions in prostate cancer
GEO Series GSE214332. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Saturation genome Editing of BRCA2 variants from C-terminal DNA binding domain
GEO Series GSE248438. Mus musculus. 398 samples. Type: Other.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.