Find research datasets worth reusing
Search datasets from major research repositories and use ShareScore to quickly assess how well each record supports discovery, access, and reuse.
225
datasets available to search
ShareScore release 0.7.1
Dataset results
225 results for “health-related quality of life”
Effect of Spiriva® on Health-related Quality of Life in Chronic Obstructive Pulmonary Disease (COPD) Patients Who Stopped Smoking During Treatment.
ClinicalTrials.gov study NCT02172547. IPD Sharing: Not stated. Countries: 0. Publications: 0.
Baseline association between Health Eating Index 2015 and health-related quality of life in breast cancer survivors enrolled in a randomized trial
<p><span>Quality of life significantly affects health outcomes in cancer patients. However, evidence on the association between diet quality and quality of life in cancer survivors is sparse. The aim of this study was to evaluate the associations between an a priori diet quality index, the Healthy Eating Index 2015 (HEI-2015) and quality of life, assessed through a validated questionnaire in women with a breast cancer diagnosis. Higher HEI-2015 score was positively associated with summary quality of life score, with functional scale and inversely associated with symptoms scale. Significant associations were also found between single HEI-components and overall quality of life scores. These results suggest that higher quality of diet could positively affect quality of life of breast cancer survivors living in a Mediterranean country, highlighting the need to implement nutritional treatment in breast cancer survivors as part of a multidisciplinary approach to improve quality of life and related health outcomes.</span></p>
Trajectories of Health-Related Quality of Life, Health Literacy, and Self-Efficacy in Curatively-Treated Patients with Esophageal Cancer: A Longitudinal Single-Center Study in Italy
<p>Dataset from Trajectories of Health-Related Quality of Life, Health Literacy, and Self-Efficacy in Curatively-Treated Patients with Esophageal Cancer: A Longitudinal Single-Center Study in Italy <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Arianna Magon</a>, RN, MSN, PhD, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Rosario Caruso</a>, PhD, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Andrea Sironi</a>, MD, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Sabrina Mirabella</a>, RN, MSN, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Federica Dellafiore</a>, PhD, RN, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Cristina Arrigoni</a>, RN, MSc, <a href="https://journals.sagepub.com/doi/full/10.1177/23743735211060769">Luigi Bonavina</a>, MD, FACS <a href="https://doi.org/10.1177%2F23743735211060769">https://doi.org/10.1177/23743735211060769</a> </p> <p>Abstract</p> <p>This prospective longitudinal study aimed to describe the trajectories of HRQoL, health literacy, and self-efficacy in patients with esophageal cancer, which have been thus far poorly described. Data were collected at baseline (preoperative phase) and in the postoperative period (two weeks, and one, two, and three months after esophagectomy). The study hypothesis was that health literacy and self-efficacy might predict better health status and quality of life over time. Forty-five patients were enrolled between 2018 and 2019. HRQoL, health literacy, and self-efficacy were assessed using validated scales. The ability to analyze information to exert greater control over life events critically (critical health literacy) (η<sup>2</sup><em>p</em> =&thinsp;0.660) and the individual's confidence in dealing with challenging tasks (self-efficacy) (η<sup>2</sup><em>p</em> =&thinsp;0.501) strongly predicted the scores of general health status over time. Overall, the functional status improved at 3 months after surgery, and this trend paralleled the decline of cancer-specific and surgery-related symptoms. In conclusion, researchers and clinicians should pay greater attention to optimizing baseline health literacy and self-efficacy levels. Future educational and motivational interventions should be further tested and possibly integrated into the prehabilitation programs.</p>
Data from: Health-related quality of life and associated factors after hip fracture. Results from a six-month prospective cohort study
<p>This is the raw data and R code from the paper "Health-related quality of life and associated factors after hip fracture. Results from a six-month prospective cohort study" (project EMAAge).</p> <p><strong>Background.</strong> Hip fractures are a major public health problem with increasing relevance in aging societies. They are associated with high mortality rates, morbidity, and loss of independence. The aim of the EMAAge study was to determine the impact of hip fractures on patient-reported health-related quality of life (HRQOL), and to identify potential risk factors for worse outcomes. </p> <p><strong>Methods.</strong> EMAAge is a multicenter, prospective cohort study of patients who suffered a hip fracture. Patients or, if necessary, proxies were interviewed after initial treatment and after six months using standardized questionnaires including the EQ-5D-5L instrument, the Oxford Hip Score, the PHQ-4, the Short Nutritional Assessment Questionnaire, and items on patients’ living situation. Medical data on diagnoses, comorbidities, medications, and hospital care were derived from hospital information systems. </p> <p><strong>Results. </strong>A total of 326 patients were included. EQ-5D index values decreased from a mean of 0.70 at baseline to 0.63 at six months. The mean self-rated health on the EQ-VAS decreased from 69.9 to 59.4. Multivariable linear regression models revealed three relevant associated factors with the six-months EQ-5D index: symptoms of depression and anxiety, pre-fracture limitations in activities of daily living, and no referral to a rehabilitation facility had a negative impact. In addition, the six-months EQ-VAS was negatively associated with polypharmacy, living in a facility, and migration background. </p> <p><strong>Conclusions. </strong>Hip fractures have a substantial negative impact on patients’ HRQOL. Our results suggest that there are modifying factors that need further investigation including polypharmacy and migration background. Structured and timely rehabilitation seems to be a protective factor.</p>
Is SF-12 a valid and reliable measurement of health-related quality of life among adults with Marfan syndrome? A confirmatory study
<p>Dataset from Udugampolage N, Caruso R, Panetta M, Callus E, Dellafiore F, Magon A, Marelli S, Pini A. Is SF-12 a valid and reliable measurement of health-related quality of life among adults with Marfan syndrome? A confirmatory study. PLoS One. 2021 Jun 9;16(6):e0252864. doi: 10.1371/journal.pone.0252864. PMID: 34106976; PMCID: PMC8189474.</p> <p>Abstract</p> <p><strong>Introduction: </strong>The structural validity and reliability of the Short-Form Health Survey 12 (SF-12) has not yet been tested in adults with the Marfan syndrome (MFS). This gap could undermine an evidence-grounded practice and research, especially considering that the need to assess health-related quality of life in patients with MFS has increased due to the improved life expectancy of these patients and the need to identify their determinants of quality of life. For this reason, this study aimed to confirm the dimensionality (structural validity) of the SF-12, its concurrent validity, and its reliability (internal consistency).</p> <p><strong>Methods: </strong>We performed a cross-sectional study in a convenience sample of 111 Italian adults with MFS, collecting anamnestic and socio-demographic information, the SF-12, and short-form Health Survey 36 (SF-36). A confirmatory factor analysis was performed to verify whether the items of SF-12 related to physical restrictions, physical functioning, and bodily pain were retained by the physical summary component of the SF-12. The items referred to the role limitations due to emotional issues, social functioning, and mental health were retained by the mental summary component (MCS12). SF-36 was used to assess the concurrent validity of SF-12, hypothesizing positive correlations among the equivalent summary scores.</p> <p><strong>Results: </strong>The two-factor structural solution resulted in fitting the sample statistics adequately. The internal consistency was adequate for the two factors. Furthermore, the physical and mental summary scores of the SF-36 were positively correlated with their equivalent summary scores derived from the SF-12.</p> <p><strong>Conclusions: </strong>This study confirmed the factor structure of the SF-12. Therefore, the use of SF-12 in clinical practice and research for assessing the health-related quality of life among adults with MFS is evidence-grounded. Future research is recommended to determine whether the SF-12 shows measurement invariance in different national contexts and determine eventual demographic variation in the SF-12 scores among patients with MFS.</p>
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.