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268
datasets available to search
ShareScore release 0.9.0
Dataset results
268 results for “polyploids”
Clonal evolution through loss of chromosomes and subsequent polyploidization in chondrosarcoma
GEO Series GSE25985. Homo sapiens. 16 samples. Type: Genome variation profiling by SNP array.
Homology-mediated inter-chromosomal interactions in hexaploid wheat lead to specific subgenome territories following polyploidization and introgression
GEO Series GSE139020. Triticum aestivum. 9 samples. Type: Methylation profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Expression profiling by high throughput sequencing; Other.
Polyploid Giant Cancer Cells are dependent on cholesterol for progeny formation through amitotic division
GEO Series GSE195919. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
Targeting polyploid giant cancer cells potentiates a therapeutic response and overcomes resistance to PARP inhibitors in ovarian cancer
GEO Series GSE229119. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.
Gene expression changes during aging in polyploid and diploid hepatocytes
GEO Series GSE161171. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing.
Subgenome-dominant expression and alternative splicing in response to pathogen stress in polyploid Brassica napus and progenitors
GEO Series GSE201225. Brassica napus; Brassica oleracea; Brassica rapa. 24 samples. Type: Expression profiling by high throughput sequencing.
Single-cell RNA sequencing of CCNB1+, polyploid, and diploid human iPSC-derived cardiomyocytes
GEO Series GSE147249. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
RNA-Seq analysis of 4N and 2N RPE1 cells following polyploid induction via cytokinesis failure or Aurora kinase inhibition [tpo3]
GEO Series GSE86101. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Polyploidization of mesenchymal cells is associated with suppression of the non-coding RNA H19 and with reduced tumorigenicity
GEO Series GSE39410. Mus musculus. 6 samples. Type: Expression profiling by array.
Polyploid hepatocytes are protected from cancer but maintain regenerative capacity in chronic liver disease
GEO Series GSE145084. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.
Murine polyploid trophoblast giant cells (TGCs) from day E9.5 implantation sites (experimental) vs E9.5 diploid embryos (control)
GEO Series GSE45778. Mus musculus. 3 samples. Type: Genome variation profiling by genome tiling array.
Polyploid cancer cells reveal signatures of chemotherapy relapse [scDNA-seq]
GEO Series GSE270567. Homo sapiens. 211 samples. Type: Genome variation profiling by high throughput sequencing.
Alignment-free methods for polyploid genomes: quick and reliable genetic distance estimation
<p>Polyploid genomes pose several inherent challenges to population genetic analyses. While alignment-based methods are fundamentally limited in their applicability to polyploids, alignment-free methods bypass most of these limits. We investigated the use of Mash, a k-mer analysis tool that uses the MinHash method to reduce complexity in large genomic datasets, for basic population genetic analyses of polyploid sequences. We measured the degree to which Mash correctly estimated pairwise genetic distance in simulated haploid and polyploid short-read sequences with various levels of missing data. Mash-based estimates of genetic distance were comparable to alignment-based estimates, and were less impacted by missing data. We also used Mash to analyze publicly available short-read data for three polyploid and one diploid species, then compared Mash results to published results. For both simulated and real data, Mash accurately estimated pairwise genetic differences for polyploids as well as diploids as much as 476 times faster than alignment-based methods, though we found that Mash genetic distance estimates could be biased by per-sample read depth. Mash may be a particularly useful addition to the toolkit of polyploid geneticists for rapid confirmation of alignment-based results and for basic population genetics in reference-free systems or those with only poor quality sequence data available.</p>
Efficacy and Safety of Intravitreal Vascular Endothelial Growth Factor Trap-eye in Patients With Polyploidal Choroidal Vasculopathy
ClinicalTrials.gov study NCT02072408. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Role of Renal Progenitors and Polyploid Tubular Cell Response in Glomerular and Tubular Diseases
ClinicalTrials.gov study NCT06325059. IPD Sharing: NO. Countries: 1. Publications: 0.
Centromere evolution in Brachypodium genomes with different polyploid levels
GEO Series GSE157143. Brachypodium distachyon; Brachypodium hybridum; Brachypodium stacei. 12 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single-Cell Morphological and Transcriptome Analysis Unveil Inhibitors of Polyploid Giant Breast Cancer Cells In Vitro
GEO Series GSE248717. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
Alignment-free methods for polyploid genomes: quick and reliable genetic distance estimation
Open the record for dataset details and reuse information.
Effects of Pharmacological Polyploidization in Human iPSC-derived Cardiomyocytes
GEO Series GSE293429. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing.
microRNA (miRNA) expression profiles of murine polyploid trophoblast giant cells (TGCs) from day 9.5 implantation sites.
GEO Series GSE45784. Mus musculus. 1 samples. Type: Non-coding RNA profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.