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2,552
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ShareScore release 0.9.0
Dataset results
2,552 results for “Glioblastoma”
Expression data from PDE1C knockdown glioblastoma short-term cultures
GEO Series GSE46538. Homo sapiens. 12 samples. Type: Expression profiling by array.
Exploring the impact of chonic hypoxia on the expression of DNA repair gene in Glioblastoma and Medulloblastoma cells.
GEO Series GSE139250. Homo sapiens. 51 samples. Type: Expression profiling by high throughput sequencing.
RNA Sequencing Analysis of human glioblastoma derived cells and xenograft derived primary cells
GEO Series GSE127274. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Differential expression of murine syngeneic orthotopic glioblastoma tumour models
GEO Series GSE215123. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Array CGH analysis of glioblastomas
GEO Series GSE14823. Homo sapiens. 7 samples. Type: Genome variation profiling by genome tiling array.
Chromatin blueprint of glioblastoma stem cells reveals new subtypes with unique drug sensitivities [methylation]
GEO Series GSE109330. Homo sapiens. 27 samples. Type: Methylation profiling by array.
Genome-wide analysis of circulating tumor DNA methylation profiles in cerebrospinal fluid: a clinical trial of oncolytic virus for glioblastoma
GEO Series GSE205591. Homo sapiens. 11 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Glioblastoma stem cells
GEO Series GSE68071. Homo sapiens. 16 samples. Type: Expression profiling by array.
ChIP-seq of Pol II in glioblastoma stem cells
GEO Series GSE179110. Homo sapiens. 2 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
ChIP-seq of YY1 in glioblastoma stem cells
GEO Series GSE155834. Homo sapiens. 3 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Reversing the Warburg Effect by Promoting Oxidative Phosphorylation Reduces Glioblastoma Growth as Assessed by Two-Photon Microscopy
<p><strong>Supplementary Materials:</strong>The following are available online at www.mdpi.com/xxx/s1, Video S1: The GB cell line U87GFP+ co-cultured with organotypic brain slices demonstrated without treatment tumor growth and invasion as quantified by two-photon fluorescence microscopy, 3Dview-A.mp4; Video S2: Following treatment, i.e. reversing the Warburg effect, the tumor keeps the original size and spheric shape without any signs of invasion, 3Dview-B.mp4.</p>
Pembrolizumab alters the tumor immune landscape in a patient with dMMR glioblastoma
<p>Congenital DNA mismatch repair defects (dMMR), such as Lynch Syndrome, predispose patients to a variety of cancers and account for approximately 1% of glioblastoma cases. While few therapeutic options exist for glioblastoma, checkpoint blockade therapy has proven effective in dMMR tumors. Here we present a case study of a male in his 30s diagnosed with dMMR glioblastoma treated with pembrolizumab who experienced a partial response to therapy. Using a multiplex IHC analysis pipeline on archived slide specimens taken upon tumor resection at diagnosis and after therapeutic intervention, we quantified changes in the frequency and spatial distribution of key immune and tumor cell populations in the tissue. Notably, proliferating KI67+ macrophages and T cells increased in frequency as did KI67+ tumor cells. Therapeutic intervention remodeled the cellular spatial distribution in the tumor leading to a greater frequency of macrophage/tumor cell interactions and T cell/T cell interactions, highlighting the impact of checkpoint blockade on tumor cytoarchitecture and revealing spatial patterns indicative of advantageous immune interactions in glioma and other solid tumors treated with these agents.</p> <p>This dataset includes serial multiplex IHC staining with CD3, CD8, CD4, IBA1, CD68, PD-1, PD-L1, KI67, hematoxylin (HEMA), and H&E (HNE) performed on 3 difference tumor tissue samples taken from a patient with Lynch Syndrome Associated glioblastoma.</p> <p>N20-11-2E = 1st Resection</p> <p>S21-030818-B1-6 = 2nd Resection</p> <p>S21-15696-A1(35) = 3rd Resection</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.