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718
datasets available to search
ShareScore release 0.9.0
Dataset results
718 results for “Constipation”
Urotherapy vs. Urotherapy With Constipation Treatment for Nocturnal Enuresis
ClinicalTrials.gov study NCT02337413. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Effects of Probiotics (BioKid LR - Contains Nine Different Species of Probiotics Bacteria Including L. Reuteri) in Children With Functional Constipation
ClinicalTrials.gov study NCT06959758. IPD Sharing: UNDECIDED. Countries: 1. Publications: 6.
To Determine the Effect of Forlax® Treatment in Children With Chronic Constipation Who May Also Suffer From Soiling/ Faecal Incontinence.
ClinicalTrials.gov study NCT00255372. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Contribution of Percutaneous Endoscopic Caecostomie in the Management of Severe Constipation Refractory to Medical Treatment
ClinicalTrials.gov study NCT02566746. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Washed Microbiota Transplantation for Chronic Constipation in Adults
ClinicalTrials.gov study NCT06106685. IPD Sharing: NO. Countries: 1. Publications: 13.
The Inside Study: Oligosaccharides Versus Placebo in Functional Constipation
ClinicalTrials.gov study NCT04282551. IPD Sharing: NO. Countries: 1. Publications: 1.
Whole-Body Vibration for Functional Constipation
ClinicalTrials.gov study NCT01609608. IPD Sharing: Not stated. Countries: 1. Publications: 2.
The Use of SennaS for Prevention of Post-operative Constipation After Urogynecologic Surgery
ClinicalTrials.gov study NCT00571896. IPD Sharing: Not stated. Countries: 1. Publications: 14.
Study to Evaluate Long-Term Tolerability and Safety of Oral Prucalopride in Chronic Constipation
ClinicalTrials.gov study NCT01070615. IPD Sharing: Not stated. Countries: 1. Publications: 1.
Probiotic-prebiotic therapy improved constipation and gut motility in Parkinson's disease: Randomised controlled trial
<p><b>Objective</b>: We determined the effectiveness of a multi-strain probiotic-prebiotic combination on constipation symptoms and gut motility in PD patients with constipation.</p> <p><b>Methods: </b>PD<b> </b>patients with constipation (ROME III criteria) were randomized to receive a multi-strain probiotic (<i>Lactobacillus sp</i> and <i>Bifidobacterium sp at </i>30 X 10<sup>9</sup> CFU) with fructo-oligosaccaride (prebiotic) or placebo (fermented milk) twice daily for 8 weeks. Primary outcomes were changes in the presence of constipation symptoms using 9 items of Garrigues Questionnaire (GQ), which included an item on bowel opening frequency. Secondary outcomes were whole gut transit time (WGTT), quality of life (PDQ39-SI), motor (MDS-UPDRS) and non-motor symptoms (NMSS).</p> <p><strong>Results:</strong> Of 55 recruited<b>, </b>48 patients completed the study: 22 received probiotic and 26 received placebo. At 8 weeks, the item on bowel opening frequency (BOF) of GQ showed a higher mean weekly BOF in the probiotic group compared to placebo [4.18 (SD 1.44) vs 2.81(SD 1.06), (mean difference 1.37, 95% CI 0.68, 2.07, uncorrected <i>p</i><0.001). Patients in the probiotic group reported five times higher odds (odds ratio=5.48, 95% CI 1.57, 19.12, uncorrected <i>p</i>=0.008) for increasing BOF (< 3 to 3-5 to >5 times/week) compared to the placebo group. Between-group differences were observed in the WGTT [77.32 (SD 55.35) hours vs 113.54 (SD 61.54) hours], (mean difference -36.22, 95% CI -68.90, -3.54, uncorrected <i>p</i>=0.030) and the mean change in WGTT [58.05 (SD 59.30) vs 20.73 (60.48) hours], (mean difference 37.32, 95% CI 4.00, 70.63, uncorrected <i>p</i>=0.028). No between-groups differences were observed in the NMSS, PDQ39-SI, MDS-UPDRS II, III, scores. Four patients in the probiotics group experienced mild reversible side effects.</p> <p><b>Conclusion:</b> This study provides Class I evidence that consumption of multi-strain probiotics with prebiotic over 8 weeks improved bowel opening frequency and whole gut transit time.</p>
Supplementary material 1 from: Rahmadi M, Ardianto C, Nurhan AD, Chasanah RA, Krismonika DI, Puspitasari AD, Suprapti B, Segaran S, Phan C-W, Khotib J (2022) Bisacodyl overcomes morphine-induced constipation by decreasing colonic Aquaporin-3 and Aquaporin-4 expression. Research Results in Pharmacology 8(4): 65-75. https://doi.org/10.3897/rrpharmacology.8.82242
The representative photos of feces with high water content and low water content
Safety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced Illness
ClinicalTrials.gov study NCT00672139. IPD Sharing: Not stated. Countries: 10. Publications: 0.
Chronic Constipation in Children Among School Children is Assuit University Children Hospital
ClinicalTrials.gov study NCT04110158. IPD Sharing: Not stated. Countries: 0. Publications: 1.
B. Lactis HN019 for Functional Constipation
ClinicalTrials.gov study NCT01463293. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Lubiprostone in Patients With Multiple Sclerosis Associated Constipation
ClinicalTrials.gov study NCT01236534. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Trial to Evaluate the Efficacy and Safety of R093877 in Patients With Chronic Idiopathic Constipation
ClinicalTrials.gov study NCT00596596. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Safety and Tolerability Extension Trial for Patients With Chronic Idiopathic Constipation
ClinicalTrials.gov study NCT01895543. IPD Sharing: Not stated. Countries: 10. Publications: 0.
The Effectiveness of Lubiprostone in Constipated Diabetics
ClinicalTrials.gov study NCT01170039. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Efficacy and Tolerability of PEG-only Laxative for Fecal Impaction and Chronic Constipation in Children
ClinicalTrials.gov study NCT01592734. IPD Sharing: Not stated. Countries: 0. Publications: 1.
Lubiprostone for Chronic Idiopathic Constipation Treatment
ClinicalTrials.gov study NCT02729909. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
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DANDI Archive for NWB datasets
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International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.