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1,274 results for “Disease Model”

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geo24/100

I3A Improves the Hepatic Mitochondrial Respiration Defects in NAFLD Disease Model

GEO Series GSE180353. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2022View details →
geo24/100

Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer's disease

GEO Series GSE273337. Mus musculus. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

CARD9 attenuates Ab pathology and modifies microglial responses in an Alzheimer’s disease mouse model

GEO Series GSE232636. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2023View details →
geo24/100

Generation of human chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases

GEO Series GSE168464. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2022View details →
geo24/100

Identification and functional impact of genomic copy number variants in zebrafish, an important human disease model (Zebrafish Strain CNVs) (CGH ZV81M 2)

GEO Series GSE28278. Danio rerio. 76 samples. Type: Genome variation profiling by genome tiling array.

openGEO-OpenDec 2011View details →
geo24/100

Heterogeneous expression of cell surface markers in human myeloma cell lines: implications for disease modelling and therapeutic targeting

GEO Series GSE250236. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2024View details →
geo24/100

Inflammasome signaling is dispensable for ß-amyloid-induced neuropathology in preclinical models of Alzheimer's disease

GEO Series GSE249611. Mus musculus. 10 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJan 2024View details →
geo24/100

Effects of inhibiting stearoyl-CoA desaturase (SCD) on the spatial transcriptome in a mouse model of Alzheimer's disease (AD)

GEO Series GSE275131. Mus musculus. 4 samples. Type: Other.

openGEO-OpenJan 2026View details →
geo24/100

Human Mesenchymal Stem Cell-derived Knee Joint-on-a-Chip for Disease Modeling and Drug Testing

GEO Series GSE162691. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenJul 2022View details →
geo24/100

Transcriptional profiling of striatum from a mouse model of Huntington's disease (Q140) crossed with Mlh1 heterozygous and homozygous mice [Mlh1_4m]

GEO Series GSE237544. Mus musculus. 48 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenFeb 2025View details →
geo24/100

Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington’s disease

GEO Series GSE42107. Mus musculus. 12 samples. Type: Expression profiling by array.

openGEO-OpenJan 2013View details →
geo24/100

Modeling late-onset Alzheimer's disease neuropathology via direct neuronal reprogramming III

GEO Series GSE267613. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2024View details →
geo24/100

Single cell RNA sequencing of heart cells in hypereosinophilia-associated heart disease model

GEO Series GSE295865. Mus musculus. 1 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenSep 2025View details →
geo24/100

Loss of cytosine-5 methylation in tRNA triggers stress responses in a disease model for Intellectual Disability

GEO Series GSE44746. Mus musculus. 21 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing; Other.

openGEO-OpenNov 2014View details →
geo24/100

Microglia sense astrocyte dysfunction and prevent disease progression in an Alexander disease model

GEO Series GSE242666. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2023View details →
geo24/100

Transcriptional Reprogramming of Brain Cells Under Anesthesia in wt and Alzheimer's Disease mouse model

GEO Series GSE245201. Mus musculus. 20 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenOct 2023View details →
geo24/100

Fully defined human PSC-derived microglia and tri-culture system reveals cell type specific potentiation of complement C3 production in a model of Alzheimer’s disease [scRNA-seq]

GEO Series GSE139550. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenNov 2020View details →
geo24/100

Vascular senescence and leak are features of the early breakdown of the blood-brain barrier in Alzheimer’s disease models.

GEO Series GSE243576. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenDec 2023View details →
geo24/100

Molecular Pathogenesis of Alzheimer's Disease Onset in a Mouse Model: Effects of Cannabidiol Treatment

GEO Series GSE304212. Mus musculus. 60 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenAug 2025View details →
geo24/100

Porcine respiratory coronavirus as a model for acute respiratory disease: mechanisms of different infection outcomes

GEO Series GSE288145. Sus scrofa. 16 samples. Type: Expression profiling by high throughput sequencing.

openGEO-OpenMay 2025View details →

ScienceDex guides

Understand access before you commit

These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.

Compare curated datasets

Allen Brain Atlas

Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.

allen-brain-atlas
neuroscienceopenDocumentation, web resources, and API references are available online.
Last verified 2026-04-30Open record

Annotated Behaviour and Observability Dataset (ABODe)

ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.

abode-home-cage
behavioral-neuroscienceopenThe DataShare record exposes download links for annotations, documentation, license text, and the zipped per-snippet data directory.
Last verified 2026-04-30Open record

DANDI Archive for NWB datasets

DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.

dandi-nwb
electrophysiologyopenPublished Dandiset metadata and archive endpoints are available through the production DANDI API.
Last verified 2026-04-30Open record

International Brain Laboratory public data

The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.

ibl
behavioral-neuroscienceopenPublic sessions can be searched and loaded from the IBL public data server through ONE.
Last verified 2026-04-29Open record

OpenNeuro

OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.

openneuro
neuroscienceopenPublished datasets are available on demand over the internet.
Last verified 2026-04-29Open record