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Dataset results
460 results for “Immunoglobulin A”
The spliceosome component Usp39 controls B cell development by regulating immunoglobulin gene rearrangement
GEO Series GSE173597. Mus musculus. 12 samples. Type: Expression profiling by high throughput sequencing; Other.
RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture
GEO Series GSE122897. Homo sapiens. 60 samples. Type: Expression profiling by high throughput sequencing.
Intravenous immunoglobulin has epigenetic, ribosomal, and immune effects in Paediatric Acute-Onset Neuropsychiatric syndrome
GEO Series GSE293230. Homo sapiens. 14 samples. Type: Expression profiling by high throughput sequencing.
Autophagy controls DNA accessibility to immunoglobulin variable regions and centroblast dynamics [scRNA-seq]
GEO Series GSE218051. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Single cell paired heavy- and light-chain immunoglobulin sequencing of sorted Lyme disease plasmablasts
GEO Series GSE114309. Homo sapiens. 76 samples. Type: Other.
Acetylated Histone Reader Brd4 functions as Repair Adaptor in Immunoglobulin Class Switch Recombination
GEO Series GSE52239. Mus musculus. 6 samples. Type: Expression profiling by array.
Mutability and hypermutation antagonize immunoglobulin codon optimality; Analysis of mouse splenic B cells.
GEO Series GSE260942. Mus musculus. 4 samples. Type: Other.
Dengue specific immunoglobulin repertoires comparison between the repeated and epitope-decreased immunizations
GEO Series GSE154371. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Characterizing adjuvants’ effects at the murine immunoglobulin repertoire level
GEO Series GSE228856. Mus musculus. 23 samples. Type: Other.
Figure 4 from: Alamsyah RM, Satari MH, Pintauli S, Iskandar S (2024) Molecular docking study of ginger (Zingiber officinale) on Immunoglobulin A for smoking cessation. Pharmacia 71: 1-6. https://doi.org/10.3897/pharmacia.71.e116751
Figure 4 Solvent-Accessible Surface Area (SASA) human secretory immunoglobulin A.
Figure 3 from: Alamsyah RM, Satari MH, Pintauli S, Iskandar S (2024) Molecular docking study of ginger (Zingiber officinale) on Immunoglobulin A for smoking cessation. Pharmacia 71: 1-6. https://doi.org/10.3897/pharmacia.71.e116751
Figure 3 RMSF of human secretory immunoglobulin A.
Figure 2 from: Alamsyah RM, Satari MH, Pintauli S, Iskandar S (2024) Molecular docking study of ginger (Zingiber officinale) on Immunoglobulin A for smoking cessation. Pharmacia 71: 1-6. https://doi.org/10.3897/pharmacia.71.e116751
Figure 2 RMSD of human secretory immunoglobulin A.
IMPACT OF HUMAN IMMUNOGLOBULIN GENETIC VARIANTS ON THE EXPRESSED ANTIBODY REPERTOIRE
<p>Tables related to the PhD thesis of Eric Engelbrecht, mentored by Corey T. Watson</p>
An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut resident plasma cells - Microbiome Analysis
<p>Dataset and code to reproduce microbiome analysis for "An epithelial cell-derived metabolite tunes immunoglobulin A secretion by gut resident plasma cells"</p> <p>Abstract:</p> <p>Immunoglobulin A (IgA) secretion by plasma cells, terminally differentiated B cells residing in the intestinal lamina propria, assures microbiome homeostasis and protects the host against enteric infections. Exposure to diet-derived and commensal-derived signals provides immune cells with organizing cues that instruct their effector function and dynamically shape intestinal immune responses at the mucosal barrier. Recent data have described metabolic and microbial inputs controlling T cell and innate lymphoid cell activation in the gut; however, whether IgA-secreting lamina propria plasma cells are tuned by local stimuli is completely unknown. While antibody secretion is considered to be imprinted during B cell differentiation and therefore largely unaffected by environmental changes, a rapid modulation of IgA levels in response to intestinal fluctuations might be beneficial to the host. Here we showed that dietary cholesterol absorption and commensal recognition by duodenal intestinal epithelial cells lead to the production of oxysterols, evolutionarily conserved lipids with immunomodulatory functions. Using conditional CH25H deleter mouse line we demonstrated that 7a,25-HC from epithelial cells is critical to restrain IgA secretion against commensal and pathogen-derived antigens in the gut. Intestinal plasma cells sense oxysterols via the chemoattractant receptor GPR183 and couple their tissue positioning with IgA secretion. Our findings revealed a new mechanism linking dietary cholesterol and humoral immune responses centered around plasma cell localization for efficient mucosal protection. </p>
Influence of Specific Immunotherapy With Pollinex Quattro (Tree-/Grass Pollen) on Allergen-specific Immunoglobulin E (IgE) Levels
ClinicalTrials.gov study NCT04389034. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Intravenous Immunoglobulin (IVIG, Bioven) Efficacy Assess for COVID-19 / SARS-CoV-2 Severe Pneumonia Complex Treatment
ClinicalTrials.gov study NCT04500067. IPD Sharing: YES. Countries: 1. Publications: 0.
Treatment of Patients With Chronic Hepatitis B With Hepatitis B Immunoglobulins
ClinicalTrials.gov study NCT05345990. IPD Sharing: NO. Countries: 1. Publications: 0.
Effect of Rabies Immunoglobulin on Immunogenicity of Post-exposure Rabies Vaccination in Obese Patients
ClinicalTrials.gov study NCT03093545. IPD Sharing: NO. Countries: 1. Publications: 0.
Efficacy and Safety in Chinese Patients with Immunoglobulin a Nephropathy (IgAN) Who Have Completed Study Nef-301
ClinicalTrials.gov study NCT05534919. IPD Sharing: NO. Countries: 1. Publications: 0.
Immunoglobulin G Therapy Dose Optimization
ClinicalTrials.gov study NCT04818177. IPD Sharing: NO. Countries: 1. Publications: 0.
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Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.