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897
datasets available to search
ShareScore release 0.9.0
Dataset results
897 results for “Therapeutic targets”
A validated single-cell-based strategy to identify diagnostic and therapeutic targets in complex diseases [study of 13 diseases]
GEO Series GSE123086. Homo sapiens. 166 samples. Type: Expression profiling by array.
DNA methylation as a therapeutic target in RB1 deficient and neuroendocrine prostate cancer and rational co-targeting with B7-H3
GEO Series GSE216054. Homo sapiens. 31 samples. Type: Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing.
TRIM24 as therapeutic target in endocrine treatment resistant breast cancer (ChIP-Seq)
GEO Series GSE246794. Homo sapiens. 49 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
VDAC2 primes Myeloma cells for BAK-dependent apoptosis by stabilizing BAK and not BAX and represents a novel therapeutic target
GEO Series GSE278750. Homo sapiens. 36 samples. Type: Expression profiling by high throughput sequencing.
PACT suppresses PKR activation through dsRNA binding and dimerization, and is a therapeutic target for triple-negative breast cancer
GEO Series GSE298233. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Protein arginine methyltransferase 5 (PRMT5) is an actionable therapeutic target in CDK4/6 inhibitor-resistant ER+/RB-deficient breast cancer [RNA-seq_siPRMT5]
GEO Series GSE236499. Homo sapiens. 12 samples. Type: Expression profiling by high throughput sequencing.
Whole-genome CRISPR screening identifies N-glycosylation as an essential pathway and a potential novel therapeutic target in CALR-mutant MPN (Pooled CRISPR Screen).
GEO Series GSE203455. Mus musculus. 1 samples. Type: Other.
Therapeutic targeting of GCB- and ABC-DLBCL by rationally designed BCL6 inhibitor
GEO Series GSE80351. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Pluripotent Reprogramming of Human AML Resets Leukemic Behavior and Models Therapeutic Targeting of Subclones [RNA-seq]
GEO Series GSE89777. Homo sapiens. 39 samples. Type: Expression profiling by high throughput sequencing.
Obesity defined molecular endotypes in the synovium of patients with osteoarthritis provides a rationale for therapeutic targeting of fibroblast subsets
GEO Series GSE219027. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
RNAi profiling of primary human AML cells identifies ROCK1 as a therapeutic target and nominates Fasudil as an anti-leukemic drug.
GEO Series GSE68925. Homo sapiens. 10 samples. Type: Expression profiling by high throughput sequencing; Genome variation profiling by high throughput sequencing; Other.
Single-cell genomics reveals a novel cell state during smooth muscle cell phenotypic switching and potential therapeutic targets for atherosclerosis in mouse and human [mouse]
GEO Series GSE155513. Mus musculus. 14 samples. Type: Expression profiling by high throughput sequencing.
Human embryonic stem cell-derived organoidal retinoblastoma reveals cancerous origin and therapeutic target
GEO Series GSE136929. Homo sapiens. 89 samples. Type: Methylation profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
DEEP SEQUENCING OF MODELS OF BREAST DUCTAL CARCINOMA IN SITU REVEALS ALDH5A1 AS A NOVEL POTENTIAL THERAPEUTIC TARGET
GEO Series GSE36863. Homo sapiens. 4 samples. Type: Expression profiling by high throughput sequencing.
Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signalling identifies therapeutic targets for Colorectal Cancer (RNA-seq)
GEO Series GSE156082. Homo sapiens. 9 samples. Type: Expression profiling by high throughput sequencing.
Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice
GEO Series GSE124538. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
Targeting polyploid giant cancer cells potentiates a therapeutic response and overcomes resistance to PARP inhibitors in ovarian cancer
GEO Series GSE229119. Homo sapiens. 28 samples. Type: Expression profiling by high throughput sequencing.
Identification of Src Family Kinases as potential therapeutic targets for chemotherapy-resistant triple negative breast cancer
GEO Series GSE204825. Homo sapiens. 64 samples. Type: Expression profiling by high throughput sequencing.
Integrated target discovery screens identify IL11 as novel therapeutic target for fibrosis
GEO Series GSE97117. Homo sapiens; Mus musculus. 212 samples. Type: Expression profiling by high throughput sequencing.
Expression of Keratin-1 Predicts Recurrence and Treatment Response in Advanced Laryngeal Cancer: A Potential Therapeutic Target
GEO Series GSE293443. Homo sapiens. 32 samples. Type: Expression profiling by high throughput sequencing.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.