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2,756
datasets available to search
ShareScore release 0.9.0
Dataset results
2,756 results for “Head and neck”
The molecular landscape and biological alterations induced by PRAS40-knockout in head and neck squamous cell carcinoma.
GEO Series GSE163613. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Evaluation of gene expression changes upon acquired resistance to anti-EGFR treatment in head and neck squamous cell carcinoma
GEO Series GSE235417. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
YTHDC1 promotes stemness maintenance and malignant progression in head and neck squamous cell carcinoma
GEO Series GSE205380. Homo sapiens. 3 samples. Type: Expression profiling by high throughput sequencing.
Impact of gas plasma-induced chronic oxidative stress on head and neck cancer
GEO Series GSE223042. Homo sapiens. 20 samples. Type: Expression profiling by array.
RNA Sequencing Reveals the Snail-Regulated Transcriptome in Head-and-Neck Squamous Cell Carcinoma.
GEO Series GSE65131. Homo sapiens. 2 samples. Type: Expression profiling by high throughput sequencing.
Head and neck squamous cell carcinomas
GEO Series GSE12020. Homo sapiens. 51 samples. Type: Genome variation profiling by genome tiling array.
Glutamine inhibition combined with CD47 blockade enhances radiotherapy-induced ferroptosis in head and neck squamous cell carcinoma [RNA-Seq]
GEO Series GSE228678. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck [ChIP-seq]
GEO Series GSE233168. Homo sapiens. 26 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Single-cell Sequencing Analysis of Head and Neck Squamous Cell Carcinoma
GEO Series GSE163872. Homo sapiens. 1 samples. Type: Expression profiling by high throughput sequencing.
Corelation between RISC complex, LINE-1 RNA and Global hypomethylation in head and Neck cancer cell line.
GEO Series GSE33493. Homo sapiens. 24 samples. Type: Expression profiling by array.
Genome-wide methylation profile of head and neck squamous cell carcioma (HNSCC)
GEO Series GSE40005. Homo sapiens. 24 samples. Type: Methylation profiling by genome tiling array.
EZH2 reads DNA 6mA to regulate survival and drug resistance of human head and neck squamous carcinoma by suppressing RIOX2-CDKN1A-NRF2 signaling axis [RNA-seq]
GEO Series GSE212451. Homo sapiens. 6 samples. Type: Expression profiling by high throughput sequencing.
RNA-seq of head and neck cell lines
GEO Series GSE211322. Homo sapiens. 24 samples. Type: Expression profiling by high throughput sequencing.
RNA sequencing of tissue resident macrophages, progenitors and tumor cells from murine head and neck tumors
GEO Series GSE139935. Mus musculus. 23 samples. Type: Expression profiling by high throughput sequencing.
Single-cell atlas of head and neck squamous cell carcinoma
GEO Series GSE140042. Homo sapiens. 18 samples. Type: Expression profiling by high throughput sequencing.
Knockdown of DKK3 decreases malignant property in head and neck squamous cell carcinoma-derived HSC-3 cells.
GEO Series GSE107403. Homo sapiens. 3 samples. Type: Expression profiling by array.
CTLA-4 blockade induces tumor pyroptosis via CD8+ T cells in head and neck squamous cell carcinoma
GEO Series GSE201367. Mus musculus. 6 samples. Type: Expression profiling by high throughput sequencing.
Epigenetic silencing by SMYD3 represses tumor intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
GEO Series GSE233495. Homo sapiens. 48 samples. Type: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing.
Dataset related to article "Predicting survival and local control after radiochemotherapy in locally advanced head and neck cancer by means of computed tomography based radiomics."
<p>PURPOSE:</p> <p>To appraise the ability of a radiomics signature to predict clinical outcome after definitive radiochemotherapy (RCT) of stage III-IV head and neck cancer.</p> <p>METHODS:</p> <p>A cohort of 110 patients was included in a retrospective analysis. Radiomics texture features were extracted from the gross tumor volumes contoured on planning computed tomography (CT) images. The cohort of patients was randomly divided into a training (70 patients) and a validation (40 patients) cohorts. Textural features were correlated to survival and control data to build predictive models. All the significant predictors of the univariate analysis were included in a multivariate model. The quality of the models was appraised by means of the concordance index (CI).</p> <p>RESULTS:</p> <p>A signature with 3 features was identified as predictive of overall survival (OS) with CI = 0.88 and 0.90 for the training and validation cohorts, respectively. A signature with 2 features was identified for progression-free survival (PFS; CI = 0.72 and 0.80); 2 features also characterized the signature for local control (LC; CI = 0.72 and 0.82). In all cases, the stratification in high- and low-risk groups for the training and validation cohorts led to significant differences in the actuarial curves. In the validation cohort the mean OS times (in months) were 78.9 ± 2.1 vs 67.4 ± 6.0 in the low- and high-risk groups, respectively, the PFS was 73.1 ± 3.7 and 50.7 ± 7.2, while the LC was 78.7 ± 2.1 and 63.9 ± 6.5.</p> <p>CONCLUSION:</p> <p>CT-based radiomic signatures that correlate with survival and control after RCT were identified and allow low- and high-risk groups of patients to be identified.</p>
Dataset related to article "Impact of hypofractionated schemes in radiotherapy for locally advanced head and neck cancer patients."
<p>OBJECTIVE:</p> <p>To analyze two cohorts of locally advanced head and neck cancer (LAHNC) patients treated with two schedules of hypofractionated radiotherapy and 5 versus 3 mm clinical target volume-planning target volume (CTV-PTV) margins.</p> <p>METHODS:</p> <p>145 patients were included. The patient cohort was divided into two groups. Group A included 97 patients treated with 69.96/54.45 grays (Gy) to the high-risk and low-risk volumes, respectively, in 33 fractions, with 5 mm margins. Group B included 48 patients treated with 66/54 Gy in 30 fractions using 3 mm margins. Toxicity was recorded according to the Common Toxicity Criteria version 3. Patient outcomes for locoregional control (LRC), disease-free survival (DFS), and overall survival (OS) were determined.</p> <p>RESULTS:</p> <p>Median follow-up was 26 months. In terms of toxicity, acute dysphagia worsened significantly (P = 0.003) in group B, whereas acute salivary toxicity tended to significance (P = 0.071). No significant late toxicity differences were recorded. Rates of LRC at 1 and 2 years were 90.1% ± 2.6% and 84.2% ± 3.4%, respectively, with superiority for group A (P = 0.045). The statistical significance remained for the low-dose level (P = 0.007) but not for high dose (P = 0.110). Rates of DFS at 1 and 2 years were 84.9% ± 3.1% and 76.5% ± 3.9%, respectively, whereas rates of OS were 95.9% ± 1.8% and 91.6% ± 2.7%, respectively. No differences were observed between the two groups in terms of DFS (P = 0.270) and OS (P = 0.152).</p> <p>CONCLUSION:</p> <p>The use of reduced CTV to PTV margins and dose reduction with hypofractionation schedule can improve the pattern of toxicity in LAHNC patients. This approach resulted in an increased rate of locoregional progression, particularly in low-risk regions.</p> <p>LEVEL OF EVIDENCE:</p> <p>4 Laryngoscope, 2019.</p>
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.