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5,978 results for “Macrophage”
Single-cell RNAseq analysis (10X Genomics Chromium) of refilled lung interstium macrophages on day 4 after depletion
GEO Series GSE193894. Mus musculus. 2 samples. Type: Expression profiling by high throughput sequencing.
Distinct macrophage populations upon physiological changes in adipose tissue [RNA-seq]
GEO Series GSE113594. Mus musculus. 27 samples. Type: Expression profiling by high throughput sequencing.
Efficacy of CD40 agonists is mediated by distinct cDC subsets and subverted by suppressive macrophages
GEO Series GSE209763. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Integrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
GEO Series GSE68798. Homo sapiens. 6 samples. Type: Genome binding/occupancy profiling by high throughput sequencing.
Macrophages reprogramming improves immunotherapy of IL-33 in peritoneal metastasis of gastric cancer
GEO Series GSE235526. Mus musculus. 16 samples. Type: Expression profiling by high throughput sequencing.
A subset of temporary resident cardiac macrophages induced by myocardial infarction limits adverse ventricular remodeling
GEO Series GSE219117. Mus musculus. 7 samples. Type: Expression profiling by high throughput sequencing.
Injury-Induced CLU-Positive Cardiomyocytes Drive Metabolic Reprogramming of Macrophage Function in Heart Regeneration [Spatial Transcriptomics]
GEO Series GSE254055. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
The impact and outcomes of cancer-macrophage fusion
GEO Series GSE209989. Mus musculus. 3 samples. Type: Expression profiling by high throughput sequencing.
Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis
GEO Series GSE284234. Mus musculus. 4 samples. Type: Expression profiling by high throughput sequencing.
Data set for Fatty acid binding protein 5 forms higher order assemblies with FLAP or COX-2 in LPS-stimulated macrophages
<p>Data set for Fatty acid binding protein 5 forms higher order assemblies with FLAP or COX-2 in LPS-stimulated macrophages</p>
Data from: Regulation of macrophage foam cell formation during nitrogen mustard (NM)-induced pulmonary fibrosis by lung lipids
Nitrogen mustard (NM) is a vesicant known to target the lung, causing acute injury which progresses to fibrosis. Evidence suggests that activated macrophages contribute to the pathologic response to NM. In these studies, we analyzed the role of lung lipids generated following NM exposure on macrophage activation and phenotype. Treatment of rats with NM (0.125 mg/kg, i.t.) resulted in a time-related increase in enlarged vacuolated macrophages in the lung. At 28 d post exposure, macrophages stained positively for Oil Red O, a marker of neutral lipids. This was correlated with an accumulation of oxidized phospholipids in lung macrophages and epithelial cells, and increases in bronchoalveolar lavage fluid (BAL) phospholipids and cholesterol. RNA-sequencing and immunohistochemical analysis revealed that lipid handling pathways under the control of the transcription factors LXR, FXR, PPAR-ɣ and SREBP were significantly altered following NM exposure. Whereas at 1-3 d post NM, FXR and the downstream oxidized low density lipoprotein receptor, Cd36, were increased, Lxr and the lipid efflux transporters, Abca1 and Abcg1, were reduced. Treatment of naïve lung macrophages with phospholipid and cholesterol enriched large aggregate fractions of BAL prepared 3 d after NM exposure resulted in upregulation of Nos2 and Ptgs2, markers of pro-inflammatory activation, while large aggregate fractions prepared 28 d post NM upregulated expression of the anti-inflammatory markers, Il10, Cd163, and Cx3cr1, and induced the formation of lipid-laden foamy macrophages. These data suggest that NM-induced alterations in lipid handling and metabolism drive macrophage foam cell formation, potentially contributing to the development of pulmonary fibrosis.
Single cell transcriptome reveals aberrant macrophage subtype and its regulatory genes in critical COVID-19 patients
<p>allGOnKEGG_June2020.gmt: Tab delimited file describing gene sets from KEGG and GO pathways</p> <p>Control1_Deprez_exprMatrix.tsv: COntrol dataset 1</p> <p>Contro2_Madissoon_lung.cellxgene.h5ad: Control dataset 2</p> <p>COVID19COMORBID_DATABASE_UDDINLAB.xls: Comorbid gene dataset. The genes which are upregulated in severe COVID19-comorbid conditions</p> <p>Final_LUNGMarker_DB_UDDINLAB.xlsx: Database consisting of canonical markers for cells associated to human lung region constructed by combining cell marker databases and thorough literature</p> <p>All files starting with GSM: Matrix(h5 file) and annotation file for bronchoalveolar lavage fluid (BALF) from 6 severe and 3 moderate COVID-19 patients and 3 healthy control (From Liao et al., 2020: PMID: 32398875)</p> <p>Human_cell_markers.txt: Markers from CellMarker database</p> <p>PanglaoDB_markers_27_Mar_2020.tsv: Markers from PanglaoDB database</p> <p>All files starting with sample: Sample Seurat processed file (sample.rds); Sample file for executing gene enrichment analysis; Sample file for lung marker database</p> <p>All files starting with Validation: Validation files used in the paper.</p> <p></p>
Figure 8 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 8 1H-NMR spectrum of FrKl3.1.3.1.
Figure 5 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 5 Peak MS no:2 retention time 5.725 minute (MW.400.0389) from FrKl3.1.3.1
Figure 4 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 4 Cromatogram LC-MS FrKl3.1.3.1.
Figure 11 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 11 Chemical structure of ergost-7-en-3-ol compound.
Figure 10 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 10 HMQC and HMBC correlation of ergost-7-en-3-ol compound.
Figure 1 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 1 A map of the sampling locations
Figure 7 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 7 FTIR Spectrum of FrKl3.1.3.1.
Figure 3 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 3 Macrophage activitas clorofom fraction A. planci FrKl3.1.3.1 and FrKl3.1.3.2.
ScienceDex guides
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These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.