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5,978 results for “Macrophage”
Figure 6 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 6 UV-Vis spectrum of FrKl3.1.3.1.
Figure 9 from: Achmad MJ, Samman A, Akbar N (2024) Action of Ergost-7-en-3- ol from (Acanthaster planci) stimulation of activity peritoneal macrophages. Pharmacia 71: 1-9. https://doi.org/10.3897/pharmacia.71.e113504
Figure 9 13C –NMR spectrum and DEPT 135 of Fr Kl3.1.3.1.
TAM Atlas (Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response)
<p>Included is the TAM atlas associated with the publication "Using a pan-cancer atlas to investigate tumour associated macrophages as regulators of immunotherapy response".</p> <p>The atlas is a Seurat (v 4.2.0) object stored as a .rds file, which can be loaded in R (v 4.2.2).</p> <p>Note this atlas does not include raw count data as these can be download from the original sources, but does include log-normalized count data, SCTransformed data and integrated data via RPCA.</p> <p>The data can be loaded into R as follows:</p> <p>mac.atlas <- readRDS('mac.atlas.zenodo.200524.rds')</p>
Data from: Bisphenol A promotes the invasive and metastatic potential of ductal carcinoma in situ and pro-tumorigenic polarization of macrophages
Increased cancer risk and immune disorders linked with exposure to environmental endocrine disruptors like bisphenol A (BPA) have been steadily reported. Nevertheless, the impacts of BPA on the breast ductal carcinoma in situ (DCIS) progression and macrophage polarization remain to be elucidated. Here, we analyzed the differentially expressed genes in BPA-exposed DCIS cells and explored BPA effects on DCIS progression and macrophage polarization in vitro and in vivo. 291 genes were differentially expressed in 10-8 M BPA-exposed DCIS cells, in which the gene ontology terms of biological processes associated with negative regulation of cell death, cell adhesion and immune response was enriched. 10-8 M BPA promoted the proliferation and migration of DCIS cells and the migration of macrophages, and upregulated the expression of M1 (NOS2) or M2 markers (Arg-1 and CD206) in macrophages. In co-culture system, the migratory capacity of both cells and the expression levels of NOS2, Arg-1 and CD206 in macrophages were significantly enhanced upon 10-8 M BPA. In a DCIS xenograft model, oral exposure to an environmentally human-relevant low dose of 2.5 µg/L BPA for 70 days via drinking water led to an ~2-fold promotion in the primary tumor growth rate and a significant enhancement of lymph node metastasis along with increased pro-tumorigenic CD206+ M2 polarization of macrophages. These results demonstrate that BPA acts as an accelerator to promote DCIS progression to invasive breast cancer by affecting DCIS cell proliferation and migration as well macrophage polarization toward a pro-tumorigenic phenotype.
Researching Alveolar Macrophage Improvements With Supplements in HIV
ClinicalTrials.gov study NCT02264860. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Phenotypic Characterization of Alveolar Macrophages 2016 (Caract-Aires-2016)
ClinicalTrials.gov study NCT03250897. IPD Sharing: Not stated. Countries: 1. Publications: 0.
RT201(Tumor Antigen-specific Macrophage Tumor Vaccine)
ClinicalTrials.gov study NCT05930301. IPD Sharing: NO. Countries: 1. Publications: 0.
Magnetic Resonance Imaging (MRI) Follow-up of Macrophagic Infiltration in MS Patients Treated With Tysabri
ClinicalTrials.gov study NCT00752778. IPD Sharing: Not stated. Countries: 1. Publications: 0.
The Role of Inflammasome in Inflammatory Macrophage in Mycobacterium Avium Complex-lung Disease and Mycobacterium Abscessus-lung Disease
ClinicalTrials.gov study NCT02005094. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Effect of an Immunotoxin on Activated Human Macrophages in Those With Allergic Rhinitis or Mild Intermittent Asthma
ClinicalTrials.gov study NCT00295737. IPD Sharing: Not stated. Countries: 1. Publications: 0.
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study
ClinicalTrials.gov study NCT02545621. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Functional Proteomics of Alveolar Macrophages
ClinicalTrials.gov study NCT00806091. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Protective Monocytes and Macrophages to Limit Decompensation and Heart Damaging
ClinicalTrials.gov study NCT04022330. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Macrophage Activation Markers in COVID-19 Patients
ClinicalTrials.gov study NCT04766294. IPD Sharing: UNDECIDED. Countries: 1. Publications: 0.
Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity (ATM)
ClinicalTrials.gov study NCT06571474. IPD Sharing: NO. Countries: 1. Publications: 0.
Macrophages, GM-CSF and MARS Proteinosis
ClinicalTrials.gov study NCT04811274. IPD Sharing: NO. Countries: 1. Publications: 0.
Assessment of Macrophage Activation syndromE in STill's Disease in Italy
ClinicalTrials.gov study NCT06992505. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Macrophage Programing in Acute Lung Injury: MiniBAL
ClinicalTrials.gov study NCT05767671. IPD Sharing: NO. Countries: 1. Publications: 0.
Granulocyte-macrophage Colony-stimulating Factor, Interferon and Interleukin-2 as Adjuvant Treatment for Renal Cancer
ClinicalTrials.gov study NCT01176552. IPD Sharing: Not stated. Countries: 1. Publications: 0.
Circulating " Cancer Cells / Macrophage " HYbrid Cells in Patients With Sarcoma, Part 2
ClinicalTrials.gov study NCT05427461. IPD Sharing: Not stated. Countries: 1. Publications: 0.
ScienceDex guides
Understand access before you commit
These curated guides explain access requirements, typical timelines, costs, and reuse considerations for widely used research datasets.
Allen Brain Atlas
Allen Brain Atlas is an Allen Institute collection of brain map atlases, datasets, APIs, and analysis tools covering mouse, human, and non-human primate brain resources.
Annotated Behaviour and Observability Dataset (ABODe)
ABODe is a University of Edinburgh DataShare dataset for behavior classification in group-housed mice using home-cage video, identities, bounding boxes, ground-plate positions, and annotator labels.
DANDI Archive for NWB datasets
DANDI is a BRAIN Initiative archive for publishing and sharing neurophysiology data, including electrophysiology, optophysiology, and behavioral data packaged as NWB and related standards.
International Brain Laboratory public data
The International Brain Laboratory public data releases expose standardized mouse decision-making experiments, including Neuropixels recordings, widefield calcium imaging, behavior, and session metadata accessed through the ONE API.
OpenNeuro
OpenNeuro is a free, open platform for sharing neuroimaging datasets, with public search, dataset pages, and download paths for web, S3, DataLad, and the OpenNeuro CLI.